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Abnormal breast physiology

MedGen UID:
1623013
•Concept ID:
C4531291
•
Anatomical Abnormality
HPO: HP:0031094

Definition

Any anomaly of the function of the breast. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal breast physiology

Professional guidelines

PubMed

Treatment options for molecular subtypes of endometrial cancer in 2023.
Karpel HC, Slomovitz B, Coleman RL, Pothuri B
Curr Opin Obstet Gynecol 2023 Jun 1;35(3):270-278. Epub 2023 Mar 20 doi: 10.1097/GCO.0000000000000855. PMID: 36943683
Disorders of Puberty: An Approach to Diagnosis and Management.
Klein DA, Emerick JE, Sylvester JE, Vogt KS
Am Fam Physician 2017 Nov 1;96(9):590-599. PMID: 29094880
Nutritional management in women with polycystic ovary syndrome: A review study.
Faghfoori Z, Fazelian S, Shadnoush M, Goodarzi R
Diabetes Metab Syndr 2017 Nov;11 Suppl 1:S429-S432. Epub 2017 Apr 5 doi: 10.1016/j.dsx.2017.03.030. PMID: 28416368

Recent clinical studies

Etiology

The expanding genetic and clinical landscape associated with Meier-Gorlin syndrome.
Nielsen-Dandoroff E, Ruegg MSG, Bicknell LS
Eur J Hum Genet 2023 Aug;31(8):859-868. Epub 2023 Apr 14 doi: 10.1038/s41431-023-01359-z. PMID: 37059840Free PMC Article
Breast Cancer and Major Deviations of Genetic and Gender-related Structures and Function.
Coelingh Bennink HJT, Egberts JFM, Mol JA, Roes KCB, van Diest PJ
J Clin Endocrinol Metab 2020 Sep 1;105(9) doi: 10.1210/clinem/dgaa404. PMID: 32594127
Marijuana Use in Pregnancy and While Breastfeeding.
Metz TD, Borgelt LM
Obstet Gynecol 2018 Nov;132(5):1198-1210. doi: 10.1097/AOG.0000000000002878. PMID: 30234728Free PMC Article
Sex hormones and breast cancer risk and prognosis.
Folkerd E, Dowsett M
Breast 2013 Aug;22 Suppl 2:S38-43. doi: 10.1016/j.breast.2013.07.007. PMID: 24074790
Redefining gigantomastia.
Dafydd H, Roehl KR, Phillips LG, Dancey A, Peart F, Shokrollahi K
J Plast Reconstr Aesthet Surg 2011 Feb;64(2):160-3. Epub 2010 Jun 8 doi: 10.1016/j.bjps.2010.04.043. PMID: 20965141

Diagnosis

The expanding genetic and clinical landscape associated with Meier-Gorlin syndrome.
Nielsen-Dandoroff E, Ruegg MSG, Bicknell LS
Eur J Hum Genet 2023 Aug;31(8):859-868. Epub 2023 Apr 14 doi: 10.1038/s41431-023-01359-z. PMID: 37059840Free PMC Article
Fibroepithelial tumours of the breast-a review.
Lerwill MF, Lee AHS, Tan PH
Virchows Arch 2022 Jan;480(1):45-63. Epub 2021 Sep 10 doi: 10.1007/s00428-021-03175-6. PMID: 34505197
The female adolescent breast: disorders of development.
Khaja A, DeSilva N
Curr Opin Obstet Gynecol 2019 Oct;31(5):293-297. doi: 10.1097/GCO.0000000000000564. PMID: 31356237
Klinefelter syndrome: more than hypogonadism.
Kanakis GA, Nieschlag E
Metabolism 2018 Sep;86:135-144. Epub 2018 Jan 31 doi: 10.1016/j.metabol.2017.09.017. PMID: 29382506
Carney complex.
Espiard S, Bertherat J
Front Horm Res 2013;41:50-62. Epub 2013 Mar 19 doi: 10.1159/000345669. PMID: 23652670

Therapy

Marijuana Use in Pregnancy and While Breastfeeding.
Metz TD, Borgelt LM
Obstet Gynecol 2018 Nov;132(5):1198-1210. doi: 10.1097/AOG.0000000000002878. PMID: 30234728Free PMC Article
Klinefelter syndrome: more than hypogonadism.
Kanakis GA, Nieschlag E
Metabolism 2018 Sep;86:135-144. Epub 2018 Jan 31 doi: 10.1016/j.metabol.2017.09.017. PMID: 29382506
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.
Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM; Task Force, Endocrine Society
J Clin Endocrinol Metab 2010 Jun;95(6):2536-59. doi: 10.1210/jc.2009-2354. PMID: 20525905
Choline: an essential nutrient for public health.
Zeisel SH, da Costa KA
Nutr Rev 2009 Nov;67(11):615-23. doi: 10.1111/j.1753-4887.2009.00246.x. PMID: 19906248Free PMC Article
Antipsychotic-induced hyperprolactinemia.
Bostwick JR, Guthrie SK, Ellingrod VL
Pharmacotherapy 2009 Jan;29(1):64-73. doi: 10.1592/phco.29.1.64. PMID: 19113797

Prognosis

The current advances of lncRNAs in breast cancer immunobiology research.
Fonseca-Montaño MA, Vázquez-Santillán KI, Hidalgo-Miranda A
Front Immunol 2023;14:1194300. Epub 2023 Jun 5 doi: 10.3389/fimmu.2023.1194300. PMID: 37342324Free PMC Article
Fibroepithelial tumours of the breast-a review.
Lerwill MF, Lee AHS, Tan PH
Virchows Arch 2022 Jan;480(1):45-63. Epub 2021 Sep 10 doi: 10.1007/s00428-021-03175-6. PMID: 34505197
A single-cell atlas of the healthy breast tissues reveals clinically relevant clusters of breast epithelial cells.
Bhat-Nakshatri P, Gao H, Sheng L, McGuire PC, Xuei X, Wan J, Liu Y, Althouse SK, Colter A, Sandusky G, Storniolo AM, Nakshatri H
Cell Rep Med 2021 Mar 16;2(3):100219. doi: 10.1016/j.xcrm.2021.100219. PMID: 33763657Free PMC Article
Sex hormones and breast cancer risk and prognosis.
Folkerd E, Dowsett M
Breast 2013 Aug;22 Suppl 2:S38-43. doi: 10.1016/j.breast.2013.07.007. PMID: 24074790
Carney complex.
Espiard S, Bertherat J
Front Horm Res 2013;41:50-62. Epub 2013 Mar 19 doi: 10.1159/000345669. PMID: 23652670

Clinical prediction guides

The expanding genetic and clinical landscape associated with Meier-Gorlin syndrome.
Nielsen-Dandoroff E, Ruegg MSG, Bicknell LS
Eur J Hum Genet 2023 Aug;31(8):859-868. Epub 2023 Apr 14 doi: 10.1038/s41431-023-01359-z. PMID: 37059840Free PMC Article
Clinical spectrum and pleiotropic nature of CDH1 germline mutations.
Figueiredo J, Melo S, Carneiro P, Moreira AM, Fernandes MS, Ribeiro AS, Guilford P, Paredes J, Seruca R
J Med Genet 2019 Apr;56(4):199-208. Epub 2019 Jan 19 doi: 10.1136/jmedgenet-2018-105807. PMID: 30661051Free PMC Article
Tuberous breast and predisposition to breast deformity in consanguineous.
Dessy LA, De Santo L, Onesti MG, Fallico N, Mazzocchi M
Breast J 2018 Jan;24(1):51-54. Epub 2017 May 30 doi: 10.1111/tbj.12834. PMID: 28557131
Carney complex.
Espiard S, Bertherat J
Front Horm Res 2013;41:50-62. Epub 2013 Mar 19 doi: 10.1159/000345669. PMID: 23652670
Biomarkers for breast cancer.
Beenken SW, Bland KI
Minerva Chir 2002 Aug;57(4):437-48. PMID: 12145573

Recent systematic reviews

Diagnostic and predictive value of liquid biopsy-derived exosome miR-21 for breast cancer: a systematic review and meta-analysis.
Wang M, Wang Y, Tian X, Wang Q, Huang H, Lu X, Qi M, Cao X, Lei J
Expert Rev Mol Diagn 2023 Apr;23(4):315-324. Epub 2023 Mar 29 doi: 10.1080/14737159.2023.2195552. PMID: 36992655
Circular RNAs as novel biomarkers in triple-negative breast cancer: a systematic review.
Foruzandeh Z, Dorabadi DG, Sadeghi F, Zeinali-Sehrig F, Zaefizadeh M, Rahmati Y, Alivand MR
Mol Biol Rep 2022 Oct;49(10):9825-9840. Epub 2022 May 10 doi: 10.1007/s11033-022-07502-1. PMID: 35534586
Prognostic value of the TCGA molecular classification in uterine carcinosarcoma.
Travaglino A, Raffone A, Raimondo D, Arciuolo D, Angelico G, Valente M, Scaglione G, D'alessandris N, Casadio P, Inzani F, Mollo A, Santoro A, Seracchioli R, Franco Zannoni G
Int J Gynaecol Obstet 2022 Jul;158(1):13-20. Epub 2021 Oct 11 doi: 10.1002/ijgo.13937. PMID: 34536971Free PMC Article
Systematic review of the association between oil and natural gas extraction processes and human reproduction.
Balise VD, Meng CX, Cornelius-Green JN, Kassotis CD, Kennedy R, Nagel SC
Fertil Steril 2016 Sep 15;106(4):795-819. Epub 2016 Aug 25 doi: 10.1016/j.fertnstert.2016.07.1099. PMID: 27568524Free PMC Article
Non-vector-borne transmission of Zika virus: A systematic review.
Grischott F, Puhan M, Hatz C, Schlagenhauf P
Travel Med Infect Dis 2016 Jul-Aug;14(4):313-30. Epub 2016 Jul 15 doi: 10.1016/j.tmaid.2016.07.002. PMID: 27425793

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