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Palpable purpura

MedGen UID:
1623392
•Concept ID:
C0151190
•
Finding
HPO: HP:0031363

Definition

A type of purpura in which the lesions are raised (and can therefore be appreciated upon palpation). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPalpable purpura

Professional guidelines

PubMed

Diagnosis and management of leukocytoclastic vasculitis.
Fraticelli P, Benfaremo D, Gabrielli A
Intern Emerg Med 2021 Jun;16(4):831-841. Epub 2021 Mar 13 doi: 10.1007/s11739-021-02688-x. PMID: 33713282Free PMC Article
A practical approach to the diagnosis, evaluation, and management of cutaneous small-vessel vasculitis.
Goeser MR, Laniosz V, Wetter DA
Am J Clin Dermatol 2014 Aug;15(4):299-306. doi: 10.1007/s40257-014-0076-6. PMID: 24756249
Diagnosis and management of cutaneous vasculitis in children.
Ting TV
Pediatr Clin North Am 2014 Apr;61(2):321-46. Epub 2014 Jan 21 doi: 10.1016/j.pcl.2013.11.007. PMID: 24636649

Recent clinical studies

Etiology

Interventions for preventing and treating kidney disease in IgA vasculitis.
Hahn D, Hodson EM, Craig JC
Cochrane Database Syst Rev 2023 Feb 28;2(2):CD005128. doi: 10.1002/14651858.CD005128.pub4. PMID: 36853224Free PMC Article
Diagnosing and treating ANCA-associated vasculitis: an updated review for clinical practice.
Chevet B, Cornec D, Casal Moura M, Cornec-Le Gall E, Fervenza FC, Warrington KJ, Specks U, Berti A
Rheumatology (Oxford) 2023 May 2;62(5):1787-1803. doi: 10.1093/rheumatology/keac623. PMID: 36315063
Dabigatran-related leukocytoclastic vasculitis.
An J, Garje R, Wanat KA, Leone JP
BMJ Case Rep 2017 Jan 4;2017 doi: 10.1136/bcr-2016-217423. PMID: 28052946Free PMC Article
Granulomatous vasculitis.
Marzano AV, Balice Y, Tavecchio S, Desimine C, Colombo A, Berti E
G Ital Dermatol Venereol 2015 Apr;150(2):193-202. Epub 2015 Mar 19 PMID: 25791629
Clinical approach to cutaneous vasculitis.
Chen KR, Carlson JA
Am J Clin Dermatol 2008;9(2):71-92. doi: 10.2165/00128071-200809020-00001. PMID: 18284262

Diagnosis

IgA vasculitis.
Pillebout E, Sunderkötter C
Semin Immunopathol 2021 Oct;43(5):729-738. Epub 2021 Jun 25 doi: 10.1007/s00281-021-00874-9. PMID: 34170395
Diagnosis and management of leukocytoclastic vasculitis.
Fraticelli P, Benfaremo D, Gabrielli A
Intern Emerg Med 2021 Jun;16(4):831-841. Epub 2021 Mar 13 doi: 10.1007/s11739-021-02688-x. PMID: 33713282Free PMC Article
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review.
Reamy BV, Servey JT, Williams PM
Am Fam Physician 2020 Aug 15;102(4):229-233. PMID: 32803924
Henoch-Schönlein Purpura in Children: An Updated Review.
Leung AKC, Barankin B, Leong KF
Curr Pediatr Rev 2020;16(4):265-276. doi: 10.2174/1573396316666200508104708. PMID: 32384035
Vasculitis-What Do We Have to Know? A Review of Literature.
Shavit E, Alavi A, Sibbald RG
Int J Low Extrem Wounds 2018 Dec;17(4):218-226. Epub 2018 Dec 3 doi: 10.1177/1534734618804982. PMID: 30501545

Therapy

Interventions for preventing and treating kidney disease in IgA vasculitis.
Hahn D, Hodson EM, Craig JC
Cochrane Database Syst Rev 2023 Feb 28;2(2):CD005128. doi: 10.1002/14651858.CD005128.pub4. PMID: 36853224Free PMC Article
Diagnosing and treating ANCA-associated vasculitis: an updated review for clinical practice.
Chevet B, Cornec D, Casal Moura M, Cornec-Le Gall E, Fervenza FC, Warrington KJ, Specks U, Berti A
Rheumatology (Oxford) 2023 May 2;62(5):1787-1803. doi: 10.1093/rheumatology/keac623. PMID: 36315063
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review.
Reamy BV, Servey JT, Williams PM
Am Fam Physician 2020 Aug 15;102(4):229-233. PMID: 32803924
Henoch-Schönlein Purpura in Children: An Updated Review.
Leung AKC, Barankin B, Leong KF
Curr Pediatr Rev 2020;16(4):265-276. doi: 10.2174/1573396316666200508104708. PMID: 32384035
Clinical approach to cutaneous vasculitis.
Chen KR, Carlson JA
Am J Clin Dermatol 2008;9(2):71-92. doi: 10.2165/00128071-200809020-00001. PMID: 18284262

Prognosis

IgA vasculitis.
Pillebout E, Sunderkötter C
Semin Immunopathol 2021 Oct;43(5):729-738. Epub 2021 Jun 25 doi: 10.1007/s00281-021-00874-9. PMID: 34170395
Diagnosis and management of leukocytoclastic vasculitis.
Fraticelli P, Benfaremo D, Gabrielli A
Intern Emerg Med 2021 Jun;16(4):831-841. Epub 2021 Mar 13 doi: 10.1007/s11739-021-02688-x. PMID: 33713282Free PMC Article
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review.
Reamy BV, Servey JT, Williams PM
Am Fam Physician 2020 Aug 15;102(4):229-233. PMID: 32803924
Henoch-Schönlein Purpura in Children: An Updated Review.
Leung AKC, Barankin B, Leong KF
Curr Pediatr Rev 2020;16(4):265-276. doi: 10.2174/1573396316666200508104708. PMID: 32384035
Vasculitis-What Do We Have to Know? A Review of Literature.
Shavit E, Alavi A, Sibbald RG
Int J Low Extrem Wounds 2018 Dec;17(4):218-226. Epub 2018 Dec 3 doi: 10.1177/1534734618804982. PMID: 30501545

Clinical prediction guides

Interventions for preventing and treating kidney disease in IgA vasculitis.
Hahn D, Hodson EM, Craig JC
Cochrane Database Syst Rev 2023 Feb 28;2(2):CD005128. doi: 10.1002/14651858.CD005128.pub4. PMID: 36853224Free PMC Article
Cutaneous vasculitis in SLE.
Kallas R, Goldman D, Petri MA
Lupus Sci Med 2020 Sep;7(1) doi: 10.1136/lupus-2020-000411. PMID: 32963114Free PMC Article
Acute Hemorrhagic Edema of Infancy: A Diagnostic Challenge for the General Pediatrician.
Leung AKC, Leong KF, Lam JM
Curr Pediatr Rev 2020;16(4):285-293. doi: 10.2174/1573396316666200727145039. PMID: 32718294
Henoch-Schönlein Purpura in Children: An Updated Review.
Leung AKC, Barankin B, Leong KF
Curr Pediatr Rev 2020;16(4):265-276. doi: 10.2174/1573396316666200508104708. PMID: 32384035
Life-threatening purpura and vasculitis.
Katsambas A, Stefanaki C
Clin Dermatol 2005 May-Jun;23(3):227-37. doi: 10.1016/j.clindermatol.2004.06.002. PMID: 15896537

Recent systematic reviews

Interventions for preventing and treating kidney disease in IgA vasculitis.
Hahn D, Hodson EM, Craig JC
Cochrane Database Syst Rev 2023 Feb 28;2(2):CD005128. doi: 10.1002/14651858.CD005128.pub4. PMID: 36853224Free PMC Article
Blistering eruptions in childhood Henoch-Schönlein syndrome: systematic review of the literature.
Ramelli V, Lava SA, Simonetti GD, Bianchetti MG, Ramelli GP, Milani GP
Eur J Pediatr 2017 Apr;176(4):487-492. Epub 2017 Feb 4 doi: 10.1007/s00431-017-2858-3. PMID: 28161822
Interventions for preventing and treating kidney disease in Henoch-Schönlein Purpura (HSP).
Hahn D, Hodson EM, Willis NS, Craig JC
Cochrane Database Syst Rev 2015 Aug 7;2015(8):CD005128. doi: 10.1002/14651858.CD005128.pub3. PMID: 26258874Free PMC Article
Identification of lymphoma predictors in patients with primary Sjögren's syndrome: a systematic literature review and meta-analysis.
Nishishinya MB, Pereda CA, Muñoz-Fernández S, Pego-Reigosa JM, Rúa-Figueroa I, Andreu JL, Fernández-Castro M, Rosas J, Loza Santamaría E
Rheumatol Int 2015 Jan;35(1):17-26. Epub 2014 Jun 5 doi: 10.1007/s00296-014-3051-x. PMID: 24899571

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