U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Decreased Physis Thickness

MedGen UID:
1623656
•Concept ID:
C4528298
•
Finding

Definition

A decrease in the dimension between the two surfaces, in comparison to a standard or norm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased Physis Thickness

Professional guidelines

PubMed

Nail disorders in older people, and aspects of their pharmaceutical treatment.
Murdan S
Int J Pharm 2016 Oct 30;512(2):405-411. Epub 2016 May 11 doi: 10.1016/j.ijpharm.2016.05.022. PMID: 27180233
The low keratin affinity of efinaconazole contributes to its nail penetration and fungicidal activity in topical onychomycosis treatment.
Sugiura K, Sugimoto N, Hosaka S, Katafuchi-Nagashima M, Arakawa Y, Tatsumi Y, Jo Siu W, Pillai R
Antimicrob Agents Chemother 2014 Jul;58(7):3837-42. Epub 2014 Apr 21 doi: 10.1128/AAC.00111-14. PMID: 24752277Free PMC Article

Recent clinical studies

Etiology

Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair.
Correa-Araujo L, Prieto-Abello L, Lara-Bertrand A, Medina-Solano M, Guerrero L, Camacho B, Silva-Cote I
Stem Cell Res Ther 2023 Oct 26;14(1):306. doi: 10.1186/s13287-023-03535-w. PMID: 37880776Free PMC Article
Effects of maternal diazinon exposure on frontal cerebral cortical development in mouse embryo.
Saraei F, Sadraie SH, Kaka GR, Sadoughi M, Afzal Nejad N, Sarahian N
Int J Neurosci 2023 Feb;133(2):152-158. Epub 2021 Mar 8 doi: 10.1080/00207454.2021.1896506. PMID: 33635731
Trabecular Bone Morphology Correlates With Skeletal Maturity and Body Composition in Healthy Adolescent Girls.
Mitchell DM, Caksa S, Yuan A, Bouxsein ML, Misra M, Burnett-Bowie SM
J Clin Endocrinol Metab 2018 Jan 1;103(1):336-345. doi: 10.1210/jc.2017-01785. PMID: 29121215Free PMC Article
Inhibition of FGFR Signaling Partially Rescues Hypophosphatemic Rickets in HMWFGF2 Tg Male Mice.
Xiao L, Du E, Homer-Bouthiette C, Hurley MM
Endocrinology 2017 Oct 1;158(10):3629-3646. doi: 10.1210/en.2016-1617. PMID: 28938491Free PMC Article
Placental growth patterns affect birth weight for given placental weight.
Salafia CM, Zhang J, Miller RK, Charles AK, Shrout P, Sun W
Birth Defects Res A Clin Mol Teratol 2007 Apr;79(4):281-8. doi: 10.1002/bdra.20345. PMID: 17286292

Diagnosis

Impact of Deep Learning Denoising Algorithm on Diffusion Tensor Imaging of the Growth Plate on Different Spatial Resolutions.
Santos L, Hsu HY, Nelson RR Jr, Sullivan B, Shin J, Fung M, Lebel MR, Jambawalikar S, Jaramillo D
Tomography 2024 Apr 2;10(4):504-519. doi: 10.3390/tomography10040039. PMID: 38668397Free PMC Article
Nail disorders in older people, and aspects of their pharmaceutical treatment.
Murdan S
Int J Pharm 2016 Oct 30;512(2):405-411. Epub 2016 May 11 doi: 10.1016/j.ijpharm.2016.05.022. PMID: 27180233
Age and sex dependency of cartilage T2 relaxation time mapping in MRI of children and adolescents.
Kim HK, Shiraj S, Anton CG, Horn PS, Dardzinski BJ
AJR Am J Roentgenol 2014 Mar;202(3):626-32. doi: 10.2214/AJR.13.11327. PMID: 24555601
Periostin-like-factor and Periostin in an animal model of work-related musculoskeletal disorder.
Rani S, Barbe MF, Barr AE, Litvin J
Bone 2009 Mar;44(3):502-12. Epub 2008 Nov 27 doi: 10.1016/j.bone.2008.11.012. PMID: 19095091Free PMC Article
Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.
Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS
J Clin Invest 1983 Oct;72(4):1396-409. doi: 10.1172/JCI111096. PMID: 6630513Free PMC Article

Therapy

Effects of maternal diazinon exposure on frontal cerebral cortical development in mouse embryo.
Saraei F, Sadraie SH, Kaka GR, Sadoughi M, Afzal Nejad N, Sarahian N
Int J Neurosci 2023 Feb;133(2):152-158. Epub 2021 Mar 8 doi: 10.1080/00207454.2021.1896506. PMID: 33635731
An Anatomic Study of the Proximal Tibial Epiphysis With Relevance to Percutaneous Epiphysiodesis Using Transphyseal Screws (PETS).
Do MT, McCarthy CF, Cooperman DR, Liu RW
J Pediatr Orthop 2022 Oct 1;42(9):e932-e936. Epub 2022 Aug 8 doi: 10.1097/BPO.0000000000002231. PMID: 35941093
Nail disorders in older people, and aspects of their pharmaceutical treatment.
Murdan S
Int J Pharm 2016 Oct 30;512(2):405-411. Epub 2016 May 11 doi: 10.1016/j.ijpharm.2016.05.022. PMID: 27180233
Periostin-like-factor and Periostin in an animal model of work-related musculoskeletal disorder.
Rani S, Barbe MF, Barr AE, Litvin J
Bone 2009 Mar;44(3):502-12. Epub 2008 Nov 27 doi: 10.1016/j.bone.2008.11.012. PMID: 19095091Free PMC Article
Effects of magnesium on skeletal metabolism.
Wallach S
Magnes Trace Elem 1990;9(1):1-14. PMID: 2184830

Prognosis

Percutaneous microwave ablation, perfusion, and reconstruction combined with a synthetic bone substitute in symptomatic bone cysts: a minimum of 26 months follow-up.
Huang W, Yan Y, Huang C, Liao H, Lin J, Zhang Y
Int J Hyperthermia 2024;41(1):2345382. Epub 2024 Jun 6 doi: 10.1080/02656736.2024.2345382. PMID: 38843894
Trabecular Bone Morphology Correlates With Skeletal Maturity and Body Composition in Healthy Adolescent Girls.
Mitchell DM, Caksa S, Yuan A, Bouxsein ML, Misra M, Burnett-Bowie SM
J Clin Endocrinol Metab 2018 Jan 1;103(1):336-345. doi: 10.1210/jc.2017-01785. PMID: 29121215Free PMC Article
The pattern of trabecular bone microarchitecture in the distal femur of typically developing children and its effect on processing of magnetic resonance images.
Modlesky CM, Whitney DG, Carter PT, Allerton BM, Kirby JT, Miller F
Bone 2014 Mar;60:1-7. Epub 2013 Nov 20 doi: 10.1016/j.bone.2013.11.009. PMID: 24269277Free PMC Article
Placental growth patterns affect birth weight for given placental weight.
Salafia CM, Zhang J, Miller RK, Charles AK, Shrout P, Sun W
Birth Defects Res A Clin Mol Teratol 2007 Apr;79(4):281-8. doi: 10.1002/bdra.20345. PMID: 17286292

Clinical prediction guides

Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair.
Correa-Araujo L, Prieto-Abello L, Lara-Bertrand A, Medina-Solano M, Guerrero L, Camacho B, Silva-Cote I
Stem Cell Res Ther 2023 Oct 26;14(1):306. doi: 10.1186/s13287-023-03535-w. PMID: 37880776Free PMC Article
Multiscale structural characterization of the vertebral endplate in animal models.
Wojtków M, Głowacki M, Pezowicz C
J Anat 2021 Jul;239(1):70-80. Epub 2021 Jan 31 doi: 10.1111/joa.13402. PMID: 33521970Free PMC Article
Changes in tibial bone microarchitecture in female recruits in response to 8 weeks of U.S. Army Basic Combat Training.
Hughes JM, Gaffney-Stomberg E, Guerriere KI, Taylor KM, Popp KL, Xu C, Unnikrishnan G, Staab JS, Matheny RW Jr, McClung JP, Reifman J, Bouxsein ML
Bone 2018 Aug;113:9-16. Epub 2018 Apr 27 doi: 10.1016/j.bone.2018.04.021. PMID: 29709620
Osteoblast AMP-Activated Protein Kinase Regulates Postnatal Skeletal Development in Male Mice.
Kanazawa I, Takeno A, Tanaka KI, Notsu M, Sugimoto T
Endocrinology 2018 Feb 1;159(2):597-608. doi: 10.1210/en.2017-00357. PMID: 29126229
Effects of magnesium on skeletal metabolism.
Wallach S
Magnes Trace Elem 1990;9(1):1-14. PMID: 2184830

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...