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Melanoma Metastatic in the Central Nervous System

MedGen UID:
1623731
Concept ID:
C4524683
Neoplastic Process
Synonym: Melanoma Metastatic in the CNS

Definition

A melanoma that has spread to the central nervous system from its original site of growth, through the hematogenous route. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMelanoma Metastatic in the Central Nervous System

Professional guidelines

PubMed

Lynes JP, Nwankwo AK, Sur HP, Sanchez VE, Sarpong KA, Ariyo OI, Dominah GA, Nduom EK
J Immunother Cancer 2020 May;8(1) doi: 10.1136/jitc-2019-000348. PMID: 32474411Free PMC Article
Pruitt AA
Continuum (Minneap Minn) 2017 Dec;23(6, Neuro-oncology):1580-1600. doi: 10.1212/CON.0000000000000551. PMID: 29200112
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Recent clinical studies

Etiology

Caffarel MM, Braza MS
J Exp Clin Cancer Res 2022 Nov 21;41(1):327. doi: 10.1186/s13046-022-02535-7. PMID: 36411434Free PMC Article
Ganz JC
Prog Brain Res 2022;268(1):229-258. Epub 2022 Jan 13 doi: 10.1016/bs.pbr.2021.10.034. PMID: 35074082
Tawbi HA, Forsyth PA, Algazi A, Hamid O, Hodi FS, Moschos SJ, Khushalani NI, Lewis K, Lao CD, Postow MA, Atkins MB, Ernstoff MS, Reardon DA, Puzanov I, Kudchadkar RR, Thomas RP, Tarhini A, Pavlick AC, Jiang J, Avila A, Demelo S, Margolin K
N Engl J Med 2018 Aug 23;379(8):722-730. doi: 10.1056/NEJMoa1805453. PMID: 30134131Free PMC Article
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989
Ewend MG, Carey LA, Morris DE, Harvey RD, Hensing TA
Curr Treat Options Oncol 2001 Dec;2(6):537-47. doi: 10.1007/s11864-001-0075-8. PMID: 12057099

Diagnosis

Ganz JC
Prog Brain Res 2022;268(1):229-258. Epub 2022 Jan 13 doi: 10.1016/bs.pbr.2021.10.034. PMID: 35074082
Pruitt AA
Continuum (Minneap Minn) 2021 Feb 1;27(1):121-142. doi: 10.1212/CON.0000000000000964. PMID: 33522739
Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang RJ, Luengo A, Davidson SM, Ali A, Ferraro GB, Fischer GM, Eskandari R, Kang DS, Ni J, Plasger A, Rajasekhar VK, Kastenhuber ER, Bacha S, Sriram RK, Stein BD, Bakhoum SF, Snuderl M, Cotzia P, Healey JH, Mainolfi N, Suri V, Friedman A, Manfredi M, Sabatini DM, Jones DR, Yu M, Zhao JJ, Jain RK, Keshari KR, Davies MA, Vander Heiden MG, Hernando E, Mann M, Cantley LC, Pacold ME
Cancer Discov 2020 Sep;10(9):1352-1373. Epub 2020 Jun 22 doi: 10.1158/2159-8290.CD-19-1228. PMID: 32571778Free PMC Article
Lah TT, Novak M, Breznik B
Semin Cancer Biol 2020 Feb;60:262-273. Epub 2019 Oct 22 doi: 10.1016/j.semcancer.2019.10.010. PMID: 31654711
Graber JJ, Kesari S
Curr Treat Options Oncol 2018 Jan 23;19(1):3. doi: 10.1007/s11864-018-0518-0. PMID: 29362920

Therapy

Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang RJ, Luengo A, Davidson SM, Ali A, Ferraro GB, Fischer GM, Eskandari R, Kang DS, Ni J, Plasger A, Rajasekhar VK, Kastenhuber ER, Bacha S, Sriram RK, Stein BD, Bakhoum SF, Snuderl M, Cotzia P, Healey JH, Mainolfi N, Suri V, Friedman A, Manfredi M, Sabatini DM, Jones DR, Yu M, Zhao JJ, Jain RK, Keshari KR, Davies MA, Vander Heiden MG, Hernando E, Mann M, Cantley LC, Pacold ME
Cancer Discov 2020 Sep;10(9):1352-1373. Epub 2020 Jun 22 doi: 10.1158/2159-8290.CD-19-1228. PMID: 32571778Free PMC Article
Tawbi HA, Forsyth PA, Algazi A, Hamid O, Hodi FS, Moschos SJ, Khushalani NI, Lewis K, Lao CD, Postow MA, Atkins MB, Ernstoff MS, Reardon DA, Puzanov I, Kudchadkar RR, Thomas RP, Tarhini A, Pavlick AC, Jiang J, Avila A, Demelo S, Margolin K
N Engl J Med 2018 Aug 23;379(8):722-730. doi: 10.1056/NEJMoa1805453. PMID: 30134131Free PMC Article
Drilon A, Siena S, Ou SI, Patel M, Ahn MJ, Lee J, Bauer TM, Farago AF, Wheler JJ, Liu SV, Doebele R, Giannetta L, Cerea G, Marrapese G, Schirru M, Amatu A, Bencardino K, Palmeri L, Sartore-Bianchi A, Vanzulli A, Cresta S, Damian S, Duca M, Ardini E, Li G, Christiansen J, Kowalski K, Johnson AD, Patel R, Luo D, Chow-Maneval E, Hornby Z, Multani PS, Shaw AT, De Braud FG
Cancer Discov 2017 Apr;7(4):400-409. Epub 2017 Feb 9 doi: 10.1158/2159-8290.CD-16-1237. PMID: 28183697Free PMC Article
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989
Ewend MG, Carey LA, Morris DE, Harvey RD, Hensing TA
Curr Treat Options Oncol 2001 Dec;2(6):537-47. doi: 10.1007/s11864-001-0075-8. PMID: 12057099

Prognosis

Lorusso G, Wyss CB, Kuonen F, Vannini N, Billottet C, Duffey N, Pineau R, Lan Q, Wirapati P, Barras D, Tancredi A, Lyck R, Lehr HA, Engelhardt B, Delorenzi M, Bikfalvi A, Rüegg C
Sci Transl Med 2022 Sep 7;14(661):eaax8933. doi: 10.1126/scitranslmed.aax8933. PMID: 36070364
Pruitt AA
Continuum (Minneap Minn) 2021 Feb 1;27(1):121-142. doi: 10.1212/CON.0000000000000964. PMID: 33522739
Tawbi HA, Forsyth PA, Algazi A, Hamid O, Hodi FS, Moschos SJ, Khushalani NI, Lewis K, Lao CD, Postow MA, Atkins MB, Ernstoff MS, Reardon DA, Puzanov I, Kudchadkar RR, Thomas RP, Tarhini A, Pavlick AC, Jiang J, Avila A, Demelo S, Margolin K
N Engl J Med 2018 Aug 23;379(8):722-730. doi: 10.1056/NEJMoa1805453. PMID: 30134131Free PMC Article
Ostrom QT, Wright CH, Barnholtz-Sloan JS
Handb Clin Neurol 2018;149:27-42. doi: 10.1016/B978-0-12-811161-1.00002-5. PMID: 29307358
Ewend MG, Carey LA, Morris DE, Harvey RD, Hensing TA
Curr Treat Options Oncol 2001 Dec;2(6):537-47. doi: 10.1007/s11864-001-0075-8. PMID: 12057099

Clinical prediction guides

Brozos-Vázquez EM, Rodríguez-López C, Cortegoso-Mosquera A, López-Landrove S, Muinelo-Romay L, García-González J, López-López R, León-Mateos L
Front Immunol 2023;14:1221113. Epub 2023 Nov 3 doi: 10.3389/fimmu.2023.1221113. PMID: 38022574Free PMC Article
Lynes JP, Nwankwo AK, Sur HP, Sanchez VE, Sarpong KA, Ariyo OI, Dominah GA, Nduom EK
J Immunother Cancer 2020 May;8(1) doi: 10.1136/jitc-2019-000348. PMID: 32474411Free PMC Article
Pruitt AA
Continuum (Minneap Minn) 2017 Dec;23(6, Neuro-oncology):1580-1600. doi: 10.1212/CON.0000000000000551. PMID: 29200112
Drilon A, Siena S, Ou SI, Patel M, Ahn MJ, Lee J, Bauer TM, Farago AF, Wheler JJ, Liu SV, Doebele R, Giannetta L, Cerea G, Marrapese G, Schirru M, Amatu A, Bencardino K, Palmeri L, Sartore-Bianchi A, Vanzulli A, Cresta S, Damian S, Duca M, Ardini E, Li G, Christiansen J, Kowalski K, Johnson AD, Patel R, Luo D, Chow-Maneval E, Hornby Z, Multani PS, Shaw AT, De Braud FG
Cancer Discov 2017 Apr;7(4):400-409. Epub 2017 Feb 9 doi: 10.1158/2159-8290.CD-16-1237. PMID: 28183697Free PMC Article
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Recent systematic reviews

Li C, Li K, Zhong S, Tang M, Shi X, Bao Y
Crit Rev Oncol Hematol 2024 Feb;194:104227. Epub 2024 Jan 12 doi: 10.1016/j.critrevonc.2023.104227. PMID: 38220124
Kim PH, Suh CH, Kim HS, Kim KW, Kim DY, Lee EQ, Aizer AA, Guenette JP, Huang RY
Korean J Radiol 2021 Apr;22(4):584-595. Epub 2020 Nov 26 doi: 10.3348/kjr.2020.0728. PMID: 33289357Free PMC Article
van Opijnen MP, Dirven L, Coremans IEM, Taphoorn MJB, Kapiteijn EHW
Int J Cancer 2020 Mar 15;146(6):1479-1489. Epub 2019 Nov 23 doi: 10.1002/ijc.32696. PMID: 31583684Free PMC Article
van Bussel MTJ, Beijnen JH, Brandsma D
BMC Cancer 2019 May 30;19(1):519. doi: 10.1186/s12885-019-5741-y. PMID: 31146733Free PMC Article
Chang MT, Michaelides EM
Am J Otolaryngol 2015 Nov-Dec;36(6):798-804. Epub 2015 Jun 10 doi: 10.1016/j.amjoto.2015.06.002. PMID: 26545474

Supplemental Content

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