U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nuclear Cataract Grade 4

MedGen UID:
1623861
Concept ID:
C4525726
Disease or Syndrome

Definition

A stage of nuclear sclerotic cataract marked by severe yellowing and sclerosis of the lens nucleus. (Modified LOCS II) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNuclear Cataract Grade 4

Professional guidelines

PubMed

Hernando-Calvo A, Malone E, Day D, Prawira A, Weinreb I, Yang SYC, Wong H, Rodriguez A, Jennings S, Eliason A, Wang L, Spreafico A, Siu LL, Hansen AR
Cancer Med 2023 Oct;12(20):20299-20310. Epub 2023 Oct 11 doi: 10.1002/cam4.6589. PMID: 37818869Free PMC Article
Chee SP, Wong MH, Jap A
Am J Ophthalmol 2017 Jan;173:7-15. Epub 2016 Sep 23 doi: 10.1016/j.ajo.2016.09.021. PMID: 27670621

Recent clinical studies

Etiology

Patel C, Tan Y, Nygaard S, Guo B, Carrillo C, Burgess J, Souksamone K, Nouansavanh KO, Casson R
Ophthalmic Epidemiol 2023 Feb;30(1):57-65. Epub 2022 Feb 3 doi: 10.1080/09286586.2022.2028294. PMID: 35112939
Chauhan RA, Agrawal SO, Sawarkar RR, Agrawal S
Indian J Ophthalmol 2022 Nov;70(11):3879-3882. doi: 10.4103/ijo.IJO_1607_22. PMID: 36308119Free PMC Article
Lee JH, Choo HG, Kim SW
Graefes Arch Clin Exp Ophthalmol 2016 Jun;254(6):1127-33. Epub 2016 Mar 17 doi: 10.1007/s00417-016-3316-z. PMID: 26984747
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907

Diagnosis

Katipoğlu Z, Turan M
Int Ophthalmol 2024 Feb 7;44(1):26. doi: 10.1007/s10792-024-03001-3. PMID: 38326697
Eom Y, Suh YW, Kim SW, Lee YJ, Jeon HS, Lee SY, Lee IH, Song JS, Kim HM
Graefes Arch Clin Exp Ophthalmol 2023 Jul;261(7):1923-1932. Epub 2023 Feb 24 doi: 10.1007/s00417-023-05999-1. PMID: 36826601
Pokal U, Swathi N, Rajalakshmi AR, Lokeshmaran A
Indian J Ophthalmol 2022 Oct;70(10):3550-3555. doi: 10.4103/ijo.IJO_944_22. PMID: 36190045Free PMC Article
Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555

Therapy

Hernando-Calvo A, Malone E, Day D, Prawira A, Weinreb I, Yang SYC, Wong H, Rodriguez A, Jennings S, Eliason A, Wang L, Spreafico A, Siu LL, Hansen AR
Cancer Med 2023 Oct;12(20):20299-20310. Epub 2023 Oct 11 doi: 10.1002/cam4.6589. PMID: 37818869Free PMC Article
Chang DS, Jiang Y, Kim JA, Huang S, Munoz B, Aung T, He M, Foster PJ, Friedman D
Br J Ophthalmol 2023 Sep;107(9):1264-1268. Epub 2022 May 2 doi: 10.1136/bjophthalmol-2021-320929. PMID: 35501120
Chauhan RA, Agrawal SO, Sawarkar RR, Agrawal S
Indian J Ophthalmol 2022 Nov;70(11):3879-3882. doi: 10.4103/ijo.IJO_1607_22. PMID: 36308119Free PMC Article
Yellapragada B, Hornauer S, Snyder K, Yu S, Yiu G
Ophthalmol Retina 2022 Feb;6(2):116-129. Epub 2021 Jul 2 doi: 10.1016/j.oret.2021.06.010. PMID: 34217854Free PMC Article
Klein BE, Klein R, Lee KE, Grady LM
JAMA 2006 Jun 21;295(23):2752-8. doi: 10.1001/jama.295.23.2752. PMID: 16788130

Prognosis

Lu Q, Wei L, He W, Zhang K, Wang J, Zhang Y, Rong X, Zhao Z, Cai L, He X, Wu J, Ding D, Lu Y, Zhu X
J Cataract Refract Surg 2022 May 1;48(5):528-534. doi: 10.1097/j.jcrs.0000000000000790. PMID: 34433780
Lincke JB, Dysli C, Jaggi D, Fink R, Wolf S, Zinkernagel MS
Transl Vis Sci Technol 2021 Apr 1;10(4):33. doi: 10.1167/tvst.10.4.33. PMID: 34004011Free PMC Article
Makhotkina NY, Berendschot TTJM, van den Biggelaar FJHM, Weik ARH, Nuijts RMMA
Acta Ophthalmol 2018 Jun;96(4):356-363. Epub 2018 Mar 25 doi: 10.1111/aos.13694. PMID: 29575599
Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555

Clinical prediction guides

Chauhan RA, Agrawal SO, Sawarkar RR, Agrawal S
Indian J Ophthalmol 2022 Nov;70(11):3879-3882. doi: 10.4103/ijo.IJO_1607_22. PMID: 36308119Free PMC Article
Lincke JB, Dysli C, Jaggi D, Fink R, Wolf S, Zinkernagel MS
Transl Vis Sci Technol 2021 Apr 1;10(4):33. doi: 10.1167/tvst.10.4.33. PMID: 34004011Free PMC Article
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907
Klein BE, Klein R, Lee KE, Grady LM
JAMA 2006 Jun 21;295(23):2752-8. doi: 10.1001/jama.295.23.2752. PMID: 16788130

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...