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Nuclear Cataract Grade 1

MedGen UID:: 1624135
•Concept ID:: C4525723
•: Disease or Syndrome

Definition

A stage of nuclear sclerotic cataract marked by mild yellowing and sclerosis of the lens nucleus. (Modified LOCS II) [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNuclear Cataract Grade 1

Abnormality of the eye
- Abnormal eye morphology
  - Abnormal anterior eye segment morphology
    - Abnormal lens morphology
      - Cataract
        Nuclear sclerotic cataract
        Nuclear Cataract Grade 1

Professional guidelines

PubMed

Selinexor for the treatment of recurrent or metastatic salivary gland tumors: Results from the GEMS-001 clinical trial.

Hernando-Calvo A, Malone E, Day D, Prawira A, Weinreb I, Yang SYC, Wong H, Rodriguez A, Jennings S, Eliason A, Wang L, Spreafico A, Siu LL, Hansen AR
Cancer Med 2023 Oct;12(20):20299-20310. Epub 2023 Oct 11 doi: 10.1002/cam4.6589. PMID: 37818869 Free PMC Article

Management of Severely Subluxated Cataracts Using Femtosecond Laser-Assisted Cataract Surgery.

Chee SP, Wong MH, Jap A
Am J Ophthalmol 2017 Jan;173:7-15. Epub 2016 Sep 23 doi: 10.1016/j.ajo.2016.09.021. PMID: 27670621

Nucleus management with Blumenthal technique: anterior chamber maintainer.

Malik KP, Goel R
Indian J Ophthalmol 2009 Jan-Feb;57(1):23-5. doi: 10.4103/0301-4738.43047. PMID: 19075404 Free PMC Article

See all (3)

Recent clinical studies

Etiology

Association of Patient Satisfaction with Cataract Grading in Five Types of Multifocal IOLs.

Niazi S, Gatzioufas Z, Dhubhghaill SN, Moshirfar M, Faramarzi A, Mohammadi F, Kheiri B, Peyman A, Heidari M, Doroodgar F
Adv Ther 2024 Jan;41(1):231-245. Epub 2023 Oct 27 doi: 10.1007/s12325-023-02698-5. PMID: 37884810

Prevalence of Refractive Error in Vientiane Province, Lao People's Democratic Republic.

Patel C, Tan Y, Nygaard S, Guo B, Carrillo C, Burgess J, Souksamone K, Nouansavanh KO, Casson R
Ophthalmic Epidemiol 2023 Feb;30(1):57-65. Epub 2022 Feb 3 doi: 10.1080/09286586.2022.2028294. PMID: 35112939

Exome Array Analysis of Nuclear Lens Opacity.

Loomis SJ, Klein AP, Lee KE, Chen F, Bomotti S, Truitt B, Iyengar SK, Klein R, Klein BEK, Duggal P
Ophthalmic Epidemiol 2018 Jun;25(3):215-219. Epub 2017 Nov 28 doi: 10.1080/09286586.2017.1406122. PMID: 29182452 Free PMC Article

Spherical aberration reduction in nuclear cataracts.

Lee JH, Choo HG, Kim SW
Graefes Arch Clin Exp Ophthalmol 2016 Jun;254(6):1127-33. Epub 2016 Mar 17 doi: 10.1007/s00417-016-3316-z. PMID: 26984747

The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.

Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

See all (298)

Diagnosis

Association of Patient Satisfaction with Cataract Grading in Five Types of Multifocal IOLs.

AI-based diagnosis of nuclear cataract from slit-lamp videos.

Shimizu E, Tanji M, Nakayama S, Ishikawa T, Agata N, Yokoiwa R, Nishimura H, Khemlani RJ, Sato S, Hanyuda A, Sato Y
Sci Rep 2023 Dec 12;13(1):22046. doi: 10.1038/s41598-023-49563-7. PMID: 38086904 Free PMC Article

Cataract surgery outcomes in eyes with chorioretinal coloboma.

Sahay P, Maharana PK, Mandal S, Sinha R, Agarwal T, Sharma N, Titiyal JS
J Cataract Refract Surg 2019 May;45(5):630-638. doi: 10.1016/j.jcrs.2019.01.016. PMID: 31030778

Cataract quantification using swept-source optical coherence tomography.

Brás JEG, Sickenberger W, Hirnschall N, Findl O
J Cataract Refract Surg 2018 Dec;44(12):1478-1481. Epub 2018 Nov 2 doi: 10.1016/j.jcrs.2018.08.009. PMID: 30392762

Exome Array Analysis of Nuclear Lens Opacity.

See all (123)

Therapy

Selinexor for the treatment of recurrent or metastatic salivary gland tumors: Results from the GEMS-001 clinical trial.

Cataract progression after Nd:YAG laser iridotomy in primary angle-closure suspect eyes.

Chang DS, Jiang Y, Kim JA, Huang S, Munoz B, Aung T, He M, Foster PJ, Friedman D
Br J Ophthalmol 2023 Sep;107(9):1264-1268. Epub 2022 May 2 doi: 10.1136/bjophthalmol-2021-320929. PMID: 35501120

Comparative study of FLACS vs conventional phacoemulsification for complex cataracts in vitrectomized eyes.

Cai L, Ma D, Xu X, Han X, Qiu X, Lu Y, Yang J
J Cataract Refract Surg 2022 Dec 1;48(12):1381-1387. doi: 10.1097/j.jcrs.0000000000000998. PMID: 36449671

Randomized Controlled Trial Comparing Femtosecond Laser-Assisted with Conventional Phacoemulsification on Dense Cataracts.

Chee SP, Yang Y, Wong MHY
Am J Ophthalmol 2021 Sep;229:1-7. Epub 2021 Mar 1 doi: 10.1016/j.ajo.2020.12.024. PMID: 33662301

Statin use and incident nuclear cataract.

Klein BE, Klein R, Lee KE, Grady LM
JAMA 2006 Jun 21;295(23):2752-8. doi: 10.1001/jama.295.23.2752. PMID: 16788130

See all (161)

Prognosis

Anterior vitreous detachment and retrolental material during cataract surgery: incidence and risk factors, with pathological evidence.

Lin W, Luo J, Li P, Ji M, Guan H
J Cataract Refract Surg 2023 Jun 1;49(6):578-583. doi: 10.1097/j.jcrs.0000000000001156. PMID: 36745848

Influence of Main Ocular Variables in #TheDress Perception: An Ophthalmic Survey.

González-Martín-Moro J, Contreras I, Fuentes-Vega I, Prieto-Garrido F, Castro-Rebollo M, González-Manrique M, Gómez-Sanz F, Zamora J
Perception 2021 Apr;50(4):367-378. doi: 10.1177/0301006621997341. PMID: 33840289

Exome Array Analysis of Nuclear Lens Opacity.

Cataract and Depressive Symptoms among Older Chinese Adults.

Wang H, Sun HP, Wang P, Xu Y, Pan CW
Optom Vis Sci 2016 Dec;93(12):1479-1484. doi: 10.1097/OPX.0000000000000960. PMID: 27525533

Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.

Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555

See all (112)

Clinical prediction guides

Association of Patient Satisfaction with Cataract Grading in Five Types of Multifocal IOLs.

Anterior vitreous detachment and retrolental material during cataract surgery: incidence and risk factors, with pathological evidence.

Lin W, Luo J, Li P, Ji M, Guan H
J Cataract Refract Surg 2023 Jun 1;49(6):578-583. doi: 10.1097/j.jcrs.0000000000001156. PMID: 36745848

Real-time corneal thickness changes during phacoemulsification cataract surgery.

Hu J, Zhao C, Luo Y, Kong J, Shi W, Wang T
Graefes Arch Clin Exp Ophthalmol 2023 Jun;261(6):1609-1618. Epub 2023 Jan 20 doi: 10.1007/s00417-022-05971-5. PMID: 36662235

Cataract quantification using swept-source optical coherence tomography.

Brás JEG, Sickenberger W, Hirnschall N, Findl O
J Cataract Refract Surg 2018 Dec;44(12):1478-1481. Epub 2018 Nov 2 doi: 10.1016/j.jcrs.2018.08.009. PMID: 30392762

The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.

Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

See all (146)

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Nuclear Cataract Grade 1

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Practice guidelines

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