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Refractory Extranodal Diffuse Large B-cell Lymphoma

MedGen UID:
1624258
Concept ID:
C4528746
Neoplastic Process

Definition

Extranodal diffuse large B-cell lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Extranodal Diffuse Large B-cell Lymphoma

Professional guidelines

PubMed

Voltin CA, Paccagnella A, Winkelmann M, Heger JM, Casadei B, Beckmann L, Herrmann K, Dekorsy FJ, Kutsch N, Borchmann P, Fanti S, Kunz WG, Subklewe M, Kobe C, Zinzani PL, Stelljes M, Roth KS, Drzezga A, Noppeney R, Rahbar K, Reinhardt HC, von Tresckow B, Seifert R, Albring JC, Blumenberg V, Farolfi A, Flossdorf S, Gödel P, Hanoun C
Eur J Nucl Med Mol Imaging 2024 Apr;51(5):1361-1370. Epub 2023 Dec 20 doi: 10.1007/s00259-023-06554-0. PMID: 38114616Free PMC Article
Cherng HJ, Sun R, Sugg B, Irwin R, Yang H, Le CC, Deng Q, Fayad L, Fowler NH, Parmar S, Steiner R, Hagemeister F, Nair R, Lee HJ, Rodriguez M, Samaniego F, Iyer SP, Flowers CR, Wang L, Nastoupil LJ, Neelapu SS, Ahmed S, Strati P, Green MR, Westin J
Blood 2022 Aug 4;140(5):504-515. doi: 10.1182/blood.2022015601. PMID: 35512184Free PMC Article
Abdel-Razeq H, Ma'koseh M, Mansour A, Bater R, Amarin R, Abufara A, Halahleh K, Manassra M, Alrwashdeh M, Almomani M, Zmaily M
Clin Appl Thromb Hemost 2021 Jan-Dec;27:10760296211045908. doi: 10.1177/10760296211045908. PMID: 34590497Free PMC Article

Recent clinical studies

Etiology

Beyar Katz O, Perry C, Grisariu-Greenzaid S, Yehudai-Ofir D, Luttwak E, Avni B, Zuckerman T, Sdayoor I, Stepensky P, Ringelstein-Harlev S, Bar-On Y, Libster D, Sharvit L, Amit O, Greenbaum U, Gold R, Herishanu Y, Benyamini N, Avivi I, Ram R
Eur J Haematol 2023 Jul;111(1):63-71. Epub 2023 Apr 10 doi: 10.1111/ejh.13968. PMID: 36964939
Hubbeling H, Silverman EA, Michaud L, Tomas AA, Shouval R, Flynn J, Devlin S, Wijetunga NA, Tringale KR, Batlevi C, Dahi P, Giralt S, Lin R, Park J, Scordo M, Sauter C, Shah G, Hajj C, Salles G, Schoder H, Palomba ML, Perales MA, Yahalom J, Imber BS
Transplant Cell Ther 2023 Apr;29(4):259.e1-259.e10. Epub 2022 Dec 30 doi: 10.1016/j.jtct.2022.12.021. PMID: 36587744Free PMC Article
Song Z, Xu L, Tang G, Gao L, Wang L, Ni X, Chen L, Chen J, Wang T, Feng D, Yu X, Yang J, Wang Y
Clin Chim Acta 2022 Jul 1;532:72-78. Epub 2022 Jun 2 doi: 10.1016/j.cca.2022.05.018. PMID: 35660013
Sehn LH, Salles G
N Engl J Med 2021 Mar 4;384(9):842-858. doi: 10.1056/NEJMra2027612. PMID: 33657296Free PMC Article
Vercellino L, Di Blasi R, Kanoun S, Tessoulin B, Rossi C, D'Aveni-Piney M, Obéric L, Bodet-Milin C, Bories P, Olivier P, Lafon I, Berriolo-Riedinger A, Galli E, Bernard S, Rubio MT, Bossard C, Meignin V, Merlet P, Feugier P, Le Gouill S, Ysebaert L, Casasnovas O, Meignan M, Chevret S, Thieblemont C
Blood Adv 2020 Nov 24;4(22):5607-5615. doi: 10.1182/bloodadvances.2020003001. PMID: 33180899Free PMC Article

Diagnosis

Ghione P, Ahsanuddin S, Luttwak E, Varela SB, Nakajima R, Michaud L, Gupta K, Navitski A, Straus D, Palomba ML, Moskowitz A, Noy A, Hamlin P, Matasar M, Kumar A, Falchi L, Yahalom J, Horwitz S, Zelenetz A, Younes A, Salles G, Schöder H, Joffe E
Haematologica 2024 Jan 1;109(1):200-208. doi: 10.3324/haematol.2022.282643. PMID: 37646672Free PMC Article
Vercellino L, Di Blasi R, Kanoun S, Tessoulin B, Rossi C, D'Aveni-Piney M, Obéric L, Bodet-Milin C, Bories P, Olivier P, Lafon I, Berriolo-Riedinger A, Galli E, Bernard S, Rubio MT, Bossard C, Meignin V, Merlet P, Feugier P, Le Gouill S, Ysebaert L, Casasnovas O, Meignan M, Chevret S, Thieblemont C
Blood Adv 2020 Nov 24;4(22):5607-5615. doi: 10.1182/bloodadvances.2020003001. PMID: 33180899Free PMC Article
de Groen RAL, Schrader AMR, Kersten MJ, Pals ST, Vermaat JSP
Haematologica 2019 Dec;104(12):2337-2348. Epub 2019 Nov 7 doi: 10.3324/haematol.2019.227272. PMID: 31699794Free PMC Article
Crombie J
Oncology (Williston Park) 2019 Oct 28;33(10) PMID: 31661151
Hassan M, Mandal AK, Sidhu JS, Cardenas LM
BMJ Case Rep 2019 Jul 3;12(7) doi: 10.1136/bcr-2019-229758. PMID: 31272994Free PMC Article

Therapy

Beyar Katz O, Perry C, Grisariu-Greenzaid S, Yehudai-Ofir D, Luttwak E, Avni B, Zuckerman T, Sdayoor I, Stepensky P, Ringelstein-Harlev S, Bar-On Y, Libster D, Sharvit L, Amit O, Greenbaum U, Gold R, Herishanu Y, Benyamini N, Avivi I, Ram R
Eur J Haematol 2023 Jul;111(1):63-71. Epub 2023 Apr 10 doi: 10.1111/ejh.13968. PMID: 36964939
Hubbeling H, Silverman EA, Michaud L, Tomas AA, Shouval R, Flynn J, Devlin S, Wijetunga NA, Tringale KR, Batlevi C, Dahi P, Giralt S, Lin R, Park J, Scordo M, Sauter C, Shah G, Hajj C, Salles G, Schoder H, Palomba ML, Perales MA, Yahalom J, Imber BS
Transplant Cell Ther 2023 Apr;29(4):259.e1-259.e10. Epub 2022 Dec 30 doi: 10.1016/j.jtct.2022.12.021. PMID: 36587744Free PMC Article
Song Z, Xu L, Tang G, Gao L, Wang L, Ni X, Chen L, Chen J, Wang T, Feng D, Yu X, Yang J, Wang Y
Clin Chim Acta 2022 Jul 1;532:72-78. Epub 2022 Jun 2 doi: 10.1016/j.cca.2022.05.018. PMID: 35660013
Sehn LH, Salles G
N Engl J Med 2021 Mar 4;384(9):842-858. doi: 10.1056/NEJMra2027612. PMID: 33657296Free PMC Article
Gallamini A, Zwarthoed C
Semin Nucl Med 2018 Jan;48(1):17-27. Epub 2017 Oct 14 doi: 10.1053/j.semnuclmed.2017.09.002. PMID: 29195613

Prognosis

Hubbeling H, Silverman EA, Michaud L, Tomas AA, Shouval R, Flynn J, Devlin S, Wijetunga NA, Tringale KR, Batlevi C, Dahi P, Giralt S, Lin R, Park J, Scordo M, Sauter C, Shah G, Hajj C, Salles G, Schoder H, Palomba ML, Perales MA, Yahalom J, Imber BS
Transplant Cell Ther 2023 Apr;29(4):259.e1-259.e10. Epub 2022 Dec 30 doi: 10.1016/j.jtct.2022.12.021. PMID: 36587744Free PMC Article
Song Z, Xu L, Tang G, Gao L, Wang L, Ni X, Chen L, Chen J, Wang T, Feng D, Yu X, Yang J, Wang Y
Clin Chim Acta 2022 Jul 1;532:72-78. Epub 2022 Jun 2 doi: 10.1016/j.cca.2022.05.018. PMID: 35660013
Sehn LH, Salles G
N Engl J Med 2021 Mar 4;384(9):842-858. doi: 10.1056/NEJMra2027612. PMID: 33657296Free PMC Article
Vercellino L, Di Blasi R, Kanoun S, Tessoulin B, Rossi C, D'Aveni-Piney M, Obéric L, Bodet-Milin C, Bories P, Olivier P, Lafon I, Berriolo-Riedinger A, Galli E, Bernard S, Rubio MT, Bossard C, Meignin V, Merlet P, Feugier P, Le Gouill S, Ysebaert L, Casasnovas O, Meignan M, Chevret S, Thieblemont C
Blood Adv 2020 Nov 24;4(22):5607-5615. doi: 10.1182/bloodadvances.2020003001. PMID: 33180899Free PMC Article
Gallamini A, Zwarthoed C
Semin Nucl Med 2018 Jan;48(1):17-27. Epub 2017 Oct 14 doi: 10.1053/j.semnuclmed.2017.09.002. PMID: 29195613

Clinical prediction guides

Beyar Katz O, Perry C, Grisariu-Greenzaid S, Yehudai-Ofir D, Luttwak E, Avni B, Zuckerman T, Sdayoor I, Stepensky P, Ringelstein-Harlev S, Bar-On Y, Libster D, Sharvit L, Amit O, Greenbaum U, Gold R, Herishanu Y, Benyamini N, Avivi I, Ram R
Eur J Haematol 2023 Jul;111(1):63-71. Epub 2023 Apr 10 doi: 10.1111/ejh.13968. PMID: 36964939
Hubbeling H, Silverman EA, Michaud L, Tomas AA, Shouval R, Flynn J, Devlin S, Wijetunga NA, Tringale KR, Batlevi C, Dahi P, Giralt S, Lin R, Park J, Scordo M, Sauter C, Shah G, Hajj C, Salles G, Schoder H, Palomba ML, Perales MA, Yahalom J, Imber BS
Transplant Cell Ther 2023 Apr;29(4):259.e1-259.e10. Epub 2022 Dec 30 doi: 10.1016/j.jtct.2022.12.021. PMID: 36587744Free PMC Article
Vercellino L, Di Blasi R, Kanoun S, Tessoulin B, Rossi C, D'Aveni-Piney M, Obéric L, Bodet-Milin C, Bories P, Olivier P, Lafon I, Berriolo-Riedinger A, Galli E, Bernard S, Rubio MT, Bossard C, Meignin V, Merlet P, Feugier P, Le Gouill S, Ysebaert L, Casasnovas O, Meignan M, Chevret S, Thieblemont C
Blood Adv 2020 Nov 24;4(22):5607-5615. doi: 10.1182/bloodadvances.2020003001. PMID: 33180899Free PMC Article
de Groen RAL, Schrader AMR, Kersten MJ, Pals ST, Vermaat JSP
Haematologica 2019 Dec;104(12):2337-2348. Epub 2019 Nov 7 doi: 10.3324/haematol.2019.227272. PMID: 31699794Free PMC Article
Gallamini A, Zwarthoed C
Semin Nucl Med 2018 Jan;48(1):17-27. Epub 2017 Oct 14 doi: 10.1053/j.semnuclmed.2017.09.002. PMID: 29195613

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