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Increased proportion of CD25+ mast cells

MedGen UID:
1625996
Concept ID:
C4531143
Finding
Synonym: Increased CD25+ mast cell proportion
 
HPO: HP:0031408

Definition

An increased proportion of mast cells are positive for the cell surface marker CD25 (also called interleukin-2 receptor alpha chain). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased proportion of CD25+ mast cells

Recent clinical studies

Etiology

Schwaab J, Jawhar M, Naumann N, Schmitt-Graeff A, Fabarius A, Horny HP, Cross NC, Hofmann WK, Reiter A, Metzgeroth G
Ann Hematol 2016 Mar;95(4):557-62. Epub 2016 Jan 22 doi: 10.1007/s00277-016-2598-x. PMID: 26797429
Alvarez-Twose I, Morgado JM, Sánchez-Muñoz L, García-Montero A, Mollejo M, Orfao A, Escribano L
Int J Lab Hematol 2012 Oct;34(5):445-60. Epub 2012 May 3 doi: 10.1111/j.1751-553X.2012.01427.x. PMID: 22551157
Escribano L, Orfao A, Villarrubia J, Martín F, Madruga JI, Cuevas M, Velasco JL, Rios A, San Miguel JF
Cytometry 1997 Apr 15;30(2):98-102. doi: 10.1002/(sici)1097-0320(19970415)30:2<98::aid-cyto4>3.0.co;2-9. PMID: 9149916
Frew AJ, Chan H, Lam S, Chan-Yeung M
Am J Respir Crit Care Med 1995 Feb;151(2 Pt 1):340-4. doi: 10.1164/ajrccm.151.2.7842189. PMID: 7842189
Saetta M, Di Stefano A, Maestrelli P, Ferraresso A, Drigo R, Potena A, Ciaccia A, Fabbri LM
Am Rev Respir Dis 1993 Feb;147(2):301-6. doi: 10.1164/ajrccm/147.2.301. PMID: 8430952

Diagnosis

Schwaab J, Jawhar M, Naumann N, Schmitt-Graeff A, Fabarius A, Horny HP, Cross NC, Hofmann WK, Reiter A, Metzgeroth G
Ann Hematol 2016 Mar;95(4):557-62. Epub 2016 Jan 22 doi: 10.1007/s00277-016-2598-x. PMID: 26797429
Alvarez-Twose I, Morgado JM, Sánchez-Muñoz L, García-Montero A, Mollejo M, Orfao A, Escribano L
Int J Lab Hematol 2012 Oct;34(5):445-60. Epub 2012 May 3 doi: 10.1111/j.1751-553X.2012.01427.x. PMID: 22551157
San Miguel JF, Vidriales MB, Ocio E, Mateo G, Sánchez-Guijo F, Sánchez ML, Escribano L, Bárez A, Moro MJ, Hernández J, Aguilera C, Cuello R, García-Frade J, López R, Portero J, Orfao A
Semin Oncol 2003 Apr;30(2):187-95. doi: 10.1053/sonc.2003.50074. PMID: 12720134
Escribano L, Orfao A, Villarrubia J, Martín F, Madruga JI, Cuevas M, Velasco JL, Rios A, San Miguel JF
Cytometry 1997 Apr 15;30(2):98-102. doi: 10.1002/(sici)1097-0320(19970415)30:2<98::aid-cyto4>3.0.co;2-9. PMID: 9149916

Therapy

Sawada J, Morita H, Tanaka A, Salminen S, He F, Matsuda H
Clin Exp Allergy 2007 Feb;37(2):296-303. doi: 10.1111/j.1365-2222.2006.02645.x. PMID: 17250703
Krishna MT, Madden J, Teran LM, Biscione GL, Lau LC, Withers NJ, Sandström T, Mudway I, Kelly FJ, Walls A, Frew AJ, Holgate ST
Eur Respir J 1998 Jun;11(6):1294-300. doi: 10.1183/09031936.98.11061294. PMID: 9657569
Escribano L, Orfao A, Villarrubia J, Martín F, Madruga JI, Cuevas M, Velasco JL, Rios A, San Miguel JF
Cytometry 1997 Apr 15;30(2):98-102. doi: 10.1002/(sici)1097-0320(19970415)30:2<98::aid-cyto4>3.0.co;2-9. PMID: 9149916
Frew AJ, St-Pierre J, Teran LM, Trefilieff A, Madden J, Peroni D, Bodey KM, Walls AF, Howarth PH, Carroll MP, Holgate ST
J Allergy Clin Immunol 1996 Jul;98(1):133-43. doi: 10.1016/s0091-6749(96)70235-x. PMID: 8765827

Prognosis

Alvarez-Twose I, Morgado JM, Sánchez-Muñoz L, García-Montero A, Mollejo M, Orfao A, Escribano L
Int J Lab Hematol 2012 Oct;34(5):445-60. Epub 2012 May 3 doi: 10.1111/j.1751-553X.2012.01427.x. PMID: 22551157
Escribano L, Orfao A, Villarrubia J, Martín F, Madruga JI, Cuevas M, Velasco JL, Rios A, San Miguel JF
Cytometry 1997 Apr 15;30(2):98-102. doi: 10.1002/(sici)1097-0320(19970415)30:2<98::aid-cyto4>3.0.co;2-9. PMID: 9149916

Clinical prediction guides

Alvarez-Twose I, Morgado JM, Sánchez-Muñoz L, García-Montero A, Mollejo M, Orfao A, Escribano L
Int J Lab Hematol 2012 Oct;34(5):445-60. Epub 2012 May 3 doi: 10.1111/j.1751-553X.2012.01427.x. PMID: 22551157
San Miguel JF, Vidriales MB, Ocio E, Mateo G, Sánchez-Guijo F, Sánchez ML, Escribano L, Bárez A, Moro MJ, Hernández J, Aguilera C, Cuello R, García-Frade J, López R, Portero J, Orfao A
Semin Oncol 2003 Apr;30(2):187-95. doi: 10.1053/sonc.2003.50074. PMID: 12720134
Escribano L, Orfao A, Villarrubia J, Martín F, Madruga JI, Cuevas M, Velasco JL, Rios A, San Miguel JF
Cytometry 1997 Apr 15;30(2):98-102. doi: 10.1002/(sici)1097-0320(19970415)30:2<98::aid-cyto4>3.0.co;2-9. PMID: 9149916

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