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Refractory Intravascular Large B-Cell Lymphoma

MedGen UID:
1626290
•Concept ID:
C4527335
•
Neoplastic Process
Synonym: Refractory Intravascular B-Cell Lymphoma

Definition

Intravascular large B-cell lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Intravascular Large B-Cell Lymphoma

Professional guidelines

PubMed

Radioimmunotherapy for first-line and relapse treatment of aggressive B-cell non-Hodgkin lymphoma: an analysis of 215 patients registered in the international RIT-Network.
Hohloch K, Lankeit HK, Zinzani PL, Scholz CW, Lorsbach M, Windemuth-Kieselbach C, Trümper L
Eur J Nucl Med Mol Imaging 2014 Aug;41(8):1585-92. Epub 2014 Apr 11 doi: 10.1007/s00259-014-2758-y. PMID: 24722703

Recent clinical studies

Etiology

Thrombotic Events Are Unusual Toxicities of Chimeric Antigen Receptor T-Cell Therapies.
Schorr C, Forindez J, Espinoza-Gutarra M, Mehta R, Grover N, Perna F
Int J Mol Sci 2023 May 6;24(9) doi: 10.3390/ijms24098349. PMID: 37176053Free PMC Article
Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice.
Sahashi S, Shimada K, Takagi Y, Aoki T, Kunou S, Sakamoto A, Murase A, Furukawa K, Kagaya Y, Yamaga Y, Takai M, Tokuyama K, Shimada S, Nakamura S, Kiyoi H
Int J Hematol 2023 Aug;118(2):221-230. Epub 2023 May 2 doi: 10.1007/s12185-023-03604-z. PMID: 37129802
Chimeric antigen receptor T-cell therapy following autologous transplantation for secondary central nervous system lymphoma: A case report.
Yagi Y, Kanemasa Y, Ohigashi A, Morita Y, Tamura T, Nakamura S, Otsuka Y, Kishida Y, Kageyama A, Shimizuguchi T, Toya T, Shimizu H, Najima Y, Kobayashi T, Haraguchi K, Doki N, Okuyama Y, Omuro Y, Shimoyama T
Medicine (Baltimore) 2021 Nov 5;100(44):e27733. doi: 10.1097/MD.0000000000027733. PMID: 34871273Free PMC Article

Diagnosis

Pulmonary Intravascular Large B-cell Lymphoma (IVLBCL) Disguised as an Asthma Exacerbation in a Patient with Asthma.
Takeshige T, Harada N, Sekimoto Y, Kanemaru R, Tsutsumi T, Matsuno K, Shiota S, Masuda A, Gotoh A, Asahina M, Uekusa T, Takahashi K
Intern Med 2017;56(14):1885-1891. Epub 2017 Jul 15 doi: 10.2169/internalmedicine.56.7613. PMID: 28717087Free PMC Article
Antemortem diagnosis with multiple random skin biopsies and transbronchial lung biopsy in a patient with intravascular large B-cell lymphoma, the so-called Asian variant lymphoma.
Nishizawa T, Saraya T, Ishii H, Goto H
BMJ Case Rep 2014 Mar 14;2014 doi: 10.1136/bcr-2013-202661. PMID: 24632902Free PMC Article
Intravascular large B-cell lymphoma: report of three cases and analysis of the mTOR pathway.
Shen Q, Duan X, Feng W, Nguyen N, Lapus A, Brown RE, Chen L
Int J Clin Exp Pathol 2011;4(8):782-90. Epub 2011 Nov 3 PMID: 22135726Free PMC Article
A case of intravascular large B-cell lymphoma (IVLBCL) with no abnormal findings on chest computed tomography diagnosed by random transbronchial lung biopsy.
Kaku N, Seki M, Doi S, Hayashi T, Imanishi D, Imamura Y, Kurihara S, Miyazaki T, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S
Intern Med 2010;49(24):2697-701. Epub 2010 Dec 15 doi: 10.2169/internalmedicine.49.3986. PMID: 21173545
Intravascular cytotoxic T-cell lymphoma: A case report and review of the literature.
Gleason BC, Brinster NK, Granter SR, Pinkus GS, Lindeman NI, Miller DM
J Am Acad Dermatol 2008 Feb;58(2):290-4. doi: 10.1016/j.jaad.2006.12.022. PMID: 18222325

Therapy

Treatment of refractory diffuse large B-cell lymphoma by chidamide combined with autologous stem cell transplantation: a case report.
Wu P, Ma T, Chen Y, Wang F, Chen Y, Gao J, Zhou Z, Jia Y
Anticancer Drugs 2021 Sep 1;32(8):886-889. doi: 10.1097/CAD.0000000000001093. PMID: 34145178
Pulmonary Intravascular Large B-cell Lymphoma (IVLBCL) Disguised as an Asthma Exacerbation in a Patient with Asthma.
Takeshige T, Harada N, Sekimoto Y, Kanemaru R, Tsutsumi T, Matsuno K, Shiota S, Masuda A, Gotoh A, Asahina M, Uekusa T, Takahashi K
Intern Med 2017;56(14):1885-1891. Epub 2017 Jul 15 doi: 10.2169/internalmedicine.56.7613. PMID: 28717087Free PMC Article
Antemortem diagnosis with multiple random skin biopsies and transbronchial lung biopsy in a patient with intravascular large B-cell lymphoma, the so-called Asian variant lymphoma.
Nishizawa T, Saraya T, Ishii H, Goto H
BMJ Case Rep 2014 Mar 14;2014 doi: 10.1136/bcr-2013-202661. PMID: 24632902Free PMC Article
A case of intravascular large B-cell lymphoma (IVLBCL) with no abnormal findings on chest computed tomography diagnosed by random transbronchial lung biopsy.
Kaku N, Seki M, Doi S, Hayashi T, Imanishi D, Imamura Y, Kurihara S, Miyazaki T, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S
Intern Med 2010;49(24):2697-701. Epub 2010 Dec 15 doi: 10.2169/internalmedicine.49.3986. PMID: 21173545
Intravascular cytotoxic T-cell lymphoma: A case report and review of the literature.
Gleason BC, Brinster NK, Granter SR, Pinkus GS, Lindeman NI, Miller DM
J Am Acad Dermatol 2008 Feb;58(2):290-4. doi: 10.1016/j.jaad.2006.12.022. PMID: 18222325

Prognosis

Thrombotic Events Are Unusual Toxicities of Chimeric Antigen Receptor T-Cell Therapies.
Schorr C, Forindez J, Espinoza-Gutarra M, Mehta R, Grover N, Perna F
Int J Mol Sci 2023 May 6;24(9) doi: 10.3390/ijms24098349. PMID: 37176053Free PMC Article
Intravascular large B-cell lymphoma presenting with fulminant pseudomembranous colitis.
Wang T, Ghaffar H, Grin A
Pathol Res Pract 2013 May;209(5):323-6. Epub 2013 Mar 25 doi: 10.1016/j.prp.2013.03.006. PMID: 23611409
Asymptomatic cardiac lymphoma in a hepatitis C virus-positive thalassemic patient.
Ricchi A, Carta A, Pinna GM, Cirio EM, Foddanu M, Terrosu PF, Pardini S, Fozza C, Longinotti M
Ital Heart J 2004 Apr;5(4):302-4. PMID: 15185891

Clinical prediction guides

Thrombotic Events Are Unusual Toxicities of Chimeric Antigen Receptor T-Cell Therapies.
Schorr C, Forindez J, Espinoza-Gutarra M, Mehta R, Grover N, Perna F
Int J Mol Sci 2023 May 6;24(9) doi: 10.3390/ijms24098349. PMID: 37176053Free PMC Article
Chimeric antigen receptor T-cell therapy following autologous transplantation for secondary central nervous system lymphoma: A case report.
Yagi Y, Kanemasa Y, Ohigashi A, Morita Y, Tamura T, Nakamura S, Otsuka Y, Kishida Y, Kageyama A, Shimizuguchi T, Toya T, Shimizu H, Najima Y, Kobayashi T, Haraguchi K, Doki N, Okuyama Y, Omuro Y, Shimoyama T
Medicine (Baltimore) 2021 Nov 5;100(44):e27733. doi: 10.1097/MD.0000000000027733. PMID: 34871273Free PMC Article
Radioimmunotherapy for first-line and relapse treatment of aggressive B-cell non-Hodgkin lymphoma: an analysis of 215 patients registered in the international RIT-Network.
Hohloch K, Lankeit HK, Zinzani PL, Scholz CW, Lorsbach M, Windemuth-Kieselbach C, Trümper L
Eur J Nucl Med Mol Imaging 2014 Aug;41(8):1585-92. Epub 2014 Apr 11 doi: 10.1007/s00259-014-2758-y. PMID: 24722703

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