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Nonproductive cough

MedGen UID:
163087
Concept ID:
C0850149
Sign or Symptom
Synonyms: Dry cough; Dry Cough; Dry coughing; Non-productive cough; Non-Productive Cough; Unproductive cough
SNOMED CT: Dry cough (11833005); Unproductive cough (11833005); Non-productive cough (11833005)
 
HPO: HP:0031246

Definition

A cough that does not produce phlegm or mucus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNonproductive cough

Conditions with this feature

Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 8
MedGen UID:
1841132
Concept ID:
C5830496
Disease or Syndrome
Telomere-related pulmonary fibrosis and/or bone marrow failure syndrome-8 (PFBMFT8) is an autosomal dominant disorder characterized by the onset of progressive pulmonary fibrosis in adulthood. Some affected individuals have signs of bone marrow failure, such as thrombocytopenia, or liver dysfunction, including hepatopulmonary syndrome. Other features of dyskeratosis congenita, including premature graying of the hair, may be observed. Telomeres are shortened compared to controls (Kelich et al., 2022). For a discussion of genetic heterogeneity of telomere-related pulmonary fibrosis and/or bone marrow failure, see PFBMFT1 (614742).

Professional guidelines

PubMed

Muroi Y, Undem BJ
Lung 2014 Feb;192(1):15-20. Epub 2013 Nov 24 doi: 10.1007/s00408-013-9533-x. PMID: 24272479Free PMC Article
Aliprandi P, Castelli C, Bernorio S, Dell'Abate E, Carrara M
Drugs Exp Clin Res 2004;30(4):133-41. PMID: 15553659
Plosker GL, Foster RH
Drugs 2000 Jul;60(1):177-201. doi: 10.2165/00003495-200060010-00009. PMID: 10929934

Recent clinical studies

Etiology

Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Hagmeyer L, Randerath W
Dtsch Arztebl Int 2015 Jan 23;112(4):43-50. doi: 10.3238/arztebl.2015.0043. PMID: 25797422Free PMC Article
Prescrire Int 2013 May;22(138):117-9. PMID: 23819168
Stewardson AJ, Grayson ML
Infect Dis Clin North Am 2010 Mar;24(1):7-25. doi: 10.1016/j.idc.2009.10.003. PMID: 20171542
Cannon GW
Rheum Dis Clin North Am 1997 Nov;23(4):917-37. doi: 10.1016/s0889-857x(05)70366-5. PMID: 9361161

Diagnosis

Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Watts MM, Grammer LC
Allergy Asthma Proc 2019 Nov 1;40(6):425-428. doi: 10.2500/aap.2019.40.4263. PMID: 31690386
Padem N, Saltoun C
Allergy Asthma Proc 2019 Nov 1;40(6):385-388. doi: 10.2500/aap.2019.40.4253. PMID: 31690376
Kolman KB, Losey KR
J Fam Pract 2018 Jan;67(1):39-42. PMID: 29309474
Stewardson AJ, Grayson ML
Infect Dis Clin North Am 2010 Mar;24(1):7-25. doi: 10.1016/j.idc.2009.10.003. PMID: 20171542

Therapy

Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Prescrire Int 2013 May;22(138):117-9. PMID: 23819168
Wang T, Lazar CA, Fishbein MC, Lynch JP 3rd
Semin Respir Crit Care Med 2012 Oct;33(5):498-508. Epub 2012 Sep 21 doi: 10.1055/s-0032-1325160. PMID: 23001804
Stewardson AJ, Grayson ML
Infect Dis Clin North Am 2010 Mar;24(1):7-25. doi: 10.1016/j.idc.2009.10.003. PMID: 20171542
Cannon GW
Rheum Dis Clin North Am 1997 Nov;23(4):917-37. doi: 10.1016/s0889-857x(05)70366-5. PMID: 9361161

Prognosis

Fishman JA
Semin Respir Crit Care Med 2020 Feb;41(1):141-157. Epub 2020 Jan 30 doi: 10.1055/s-0039-3399559. PMID: 32000290
Watts MM, Grammer LC
Allergy Asthma Proc 2019 Nov 1;40(6):425-428. doi: 10.2500/aap.2019.40.4263. PMID: 31690386
Kolman KB, Losey KR
J Fam Pract 2018 Jan;67(1):39-42. PMID: 29309474
Hagmeyer L, Randerath W
Dtsch Arztebl Int 2015 Jan 23;112(4):43-50. doi: 10.3238/arztebl.2015.0043. PMID: 25797422Free PMC Article
Wang T, Lazar CA, Fishbein MC, Lynch JP 3rd
Semin Respir Crit Care Med 2012 Oct;33(5):498-508. Epub 2012 Sep 21 doi: 10.1055/s-0032-1325160. PMID: 23001804

Clinical prediction guides

Watts MM, Grammer LC
Allergy Asthma Proc 2019 Nov 1;40(6):425-428. doi: 10.2500/aap.2019.40.4263. PMID: 31690386
Gopalan D, Blanchard D, Auger WR
Ann Am Thorac Soc 2016 Jul;13 Suppl 3:S222-39. doi: 10.1513/AnnalsATS.201509-623AS. PMID: 27571004
Prescrire Int 2013 May;22(138):117-9. PMID: 23819168
Blatman KH, Grammer LC
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:64-66. doi: 10.2500/aap.2012.33.3552. PMID: 22794692
Luporini G, Barni S, Marchi E, Daffonchio L
Eur Respir J 1998 Jul;12(1):97-101. doi: 10.1183/09031936.98.12010097. PMID: 9701421

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