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Decreased eosinophil count

MedGen UID:
1630945
•Concept ID:
C0854104
•
Finding
HPO: HP:0031891

Definition

Abnormal reduction in the count of eosinophils in the blood per volume. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased eosinophil count

Conditions with this feature

Eosinophilopenia
MedGen UID:
343610
•Concept ID:
C1851586
•
Disease or Syndrome
Abnormally low level of eosinophils in the blood.
See: Condition Record
Immunodeficiency 89 and autoimmunity
MedGen UID:
1794237
•Concept ID:
C5562027
•
Disease or Syndrome
Immunodeficiency-89 and autoimmunity (IMD89) is an autosomal recessive immune disorder characterized by adult onset of recurrent infections, allergies, microcytic anemia, and Crohn disease (see 266600) (Yang et al., 2020).
See: Condition Record
Eosinophilopenia
Immunodeficiency 89 and autoimmunity

Professional guidelines

PubMed

Efficacy and safety of dupilumab in the treatment of Kimura's disease.
Liu YL, Ran YT, Zhang YF, Peng XT, Xia YM, Yan HL
QJM 2024 Aug 1;117(8):575-580. doi: 10.1093/qjmed/hcae048. PMID: 38492561
Re-examination of the diagnostic criteria of tropical pulmonary eosinophilia.
Cooray JH, Ismail MM
Respir Med 1999 Sep;93(9):655-9. doi: 10.1016/s0954-6111(99)90106-3. PMID: 10542980

Recent clinical studies

Etiology

Mendelian randomization suggests a potential causal effect of eosinophil count on influenza vaccination responsiveness.
Chen H, Zhang H, Wen S, Xiu X, You D, Zhao H, Wang D, Yang Y, Shu Y
J Med Virol 2023 Jan;95(1):e28394. doi: 10.1002/jmv.28394. PMID: 36495182
The predictive value of eosinophil levels on no-reflow in patients with STEMI following PCI: a retrospective cohort study.
Mo DG, Wang CS, Liu JH, Li T
Sci Rep 2022 Oct 25;12(1):17862. doi: 10.1038/s41598-022-22988-2. PMID: 36284176Free PMC Article
Clinical characteristics of the delta variant of COVID-19 in Jingmen, China.
Bie F, Yuan W, Chen Y, Gao Q
Medicine (Baltimore) 2022 Sep 23;101(38):e30812. doi: 10.1097/MD.0000000000030812. PMID: 36197171Free PMC Article
Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China.
Huang Q, Deng X, Li Y, Sun X, Chen Q, Xie M, Liu S, Qu H, Liu S, Wang L, He G, Gong Z
Int J Clin Pharm 2020 Jun;42(3):837-845. Epub 2020 May 14 doi: 10.1007/s11096-020-01031-2. PMID: 32410206Free PMC Article
Laboratory data analysis of novel coronavirus (COVID-19) screening in 2510 patients.
Yun H, Sun Z, Wu J, Tang A, Hu M, Xiang Z
Clin Chim Acta 2020 Aug;507:94-97. Epub 2020 Apr 18 doi: 10.1016/j.cca.2020.04.018. PMID: 32315614Free PMC Article

Diagnosis

Clinical characteristics of the delta variant of COVID-19 in Jingmen, China.
Bie F, Yuan W, Chen Y, Gao Q
Medicine (Baltimore) 2022 Sep 23;101(38):e30812. doi: 10.1097/MD.0000000000030812. PMID: 36197171Free PMC Article
Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China.
Huang Q, Deng X, Li Y, Sun X, Chen Q, Xie M, Liu S, Qu H, Liu S, Wang L, He G, Gong Z
Int J Clin Pharm 2020 Jun;42(3):837-845. Epub 2020 May 14 doi: 10.1007/s11096-020-01031-2. PMID: 32410206Free PMC Article
Laboratory data analysis of novel coronavirus (COVID-19) screening in 2510 patients.
Yun H, Sun Z, Wu J, Tang A, Hu M, Xiang Z
Clin Chim Acta 2020 Aug;507:94-97. Epub 2020 Apr 18 doi: 10.1016/j.cca.2020.04.018. PMID: 32315614Free PMC Article

Therapy

Mendelian randomization suggests a potential causal effect of eosinophil count on influenza vaccination responsiveness.
Chen H, Zhang H, Wen S, Xiu X, You D, Zhao H, Wang D, Yang Y, Shu Y
J Med Virol 2023 Jan;95(1):e28394. doi: 10.1002/jmv.28394. PMID: 36495182
The predictive value of eosinophil levels on no-reflow in patients with STEMI following PCI: a retrospective cohort study.
Mo DG, Wang CS, Liu JH, Li T
Sci Rep 2022 Oct 25;12(1):17862. doi: 10.1038/s41598-022-22988-2. PMID: 36284176Free PMC Article
Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China.
Huang Q, Deng X, Li Y, Sun X, Chen Q, Xie M, Liu S, Qu H, Liu S, Wang L, He G, Gong Z
Int J Clin Pharm 2020 Jun;42(3):837-845. Epub 2020 May 14 doi: 10.1007/s11096-020-01031-2. PMID: 32410206Free PMC Article
Effects of leukotriene receptor antagonists on peripheral eosinophil counts and serum IgE levels in children with food allergy.
Yamakawa Y, Ohtsuka Y, Ohtani K, Fujii T, Nagata S, Yamashiro Y, Shimizu T
Drugs R D 2010;10(3):147-54. doi: 10.2165/11586150-000000000-00000. PMID: 20945945Free PMC Article

Prognosis

The predictive value of eosinophil levels on no-reflow in patients with STEMI following PCI: a retrospective cohort study.
Mo DG, Wang CS, Liu JH, Li T
Sci Rep 2022 Oct 25;12(1):17862. doi: 10.1038/s41598-022-22988-2. PMID: 36284176Free PMC Article

Clinical prediction guides

The predictive value of eosinophil levels on no-reflow in patients with STEMI following PCI: a retrospective cohort study.
Mo DG, Wang CS, Liu JH, Li T
Sci Rep 2022 Oct 25;12(1):17862. doi: 10.1038/s41598-022-22988-2. PMID: 36284176Free PMC Article
Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China.
Huang Q, Deng X, Li Y, Sun X, Chen Q, Xie M, Liu S, Qu H, Liu S, Wang L, He G, Gong Z
Int J Clin Pharm 2020 Jun;42(3):837-845. Epub 2020 May 14 doi: 10.1007/s11096-020-01031-2. PMID: 32410206Free PMC Article
Effects of leukotriene receptor antagonists on peripheral eosinophil counts and serum IgE levels in children with food allergy.
Yamakawa Y, Ohtsuka Y, Ohtani K, Fujii T, Nagata S, Yamashiro Y, Shimizu T
Drugs R D 2010;10(3):147-54. doi: 10.2165/11586150-000000000-00000. PMID: 20945945Free PMC Article

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