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Abnormal PR segment

MedGen UID:
1631502
•Concept ID:
C4703433
•
Finding
HPO: HP:0031596

Definition

An anomaly of the PR segment, which begins at the endpoint of the P wave and ends at the onset of the QRS complex. The PR segment is normally flat and isoelectric. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal PR segment

Professional guidelines

PubMed

Differential diagnosis between the coronavirus disease 2019 and Streptococcus pneumoniae pneumonia by thin-slice CT features.
Zhou J, Liao X, Cao J, Ling G, Ding X, Long Q
Clin Imaging 2021 Jan;69:318-323. Epub 2020 Oct 6 doi: 10.1016/j.clinimag.2020.09.012. PMID: 33045476Free PMC Article
Detection and preliminary screening of the human gene expression profile for Hirschsprung's disease.
Wang X, Wang S, Jin X, Wang N, Luo Y, Teng Y
Mol Med Rep 2016 Jan;13(1):641-50. Epub 2015 Dec 1 doi: 10.3892/mmr.2015.4633. PMID: 26648025Free PMC Article
Diagnosis and management of ischemic heart disease.
Lippi G, Franchini M, Cervellin G
Semin Thromb Hemost 2013 Mar;39(2):202-13. Epub 2013 Feb 3 doi: 10.1055/s-0032-1333543. PMID: 23378254

Recent clinical studies

Therapy

Isoprenaline induced Takotsubo syndrome: Histopathological analyses of female rat hearts.
Kołodzińska A, Czarzasta K, Szczepankiewicz B, Budnik M, Główczyńska R, Fojt A, Ilczuk T, Krasuski K, Borodzicz S, Cudnoch-Jędrzejewska A, Górnicka B, Opolski G
Cardiol J 2022;29(1):105-114. Epub 2020 Apr 24 doi: 10.5603/CJ.a2020.0057. PMID: 32329043Free PMC Article
Balancing the Photoreceptor Proteome: Proteostasis Network Therapeutics for Inherited Retinal Disease.
Faber S, Roepman R
Genes (Basel) 2019 Jul 24;10(8) doi: 10.3390/genes10080557. PMID: 31344897Free PMC Article
Hemodialysis-induced regional left ventricular systolic dysfunction.
Nie Y, Zhang Z, Zou J, Liang Y, Cao X, Liu Z, Shen B, Chen X, Ding X
Hemodial Int 2016 Oct;20(4):564-572. Epub 2016 Jun 17 doi: 10.1111/hdi.12434. PMID: 27312507
Comparative proteomics of Hirschsprung's disease.
Fan Y, Wang L, Zhang Y, Huang T, Li H, Gu H, Wang W, Yuan Z
J Proteomics 2013 Jun 12;84:176-84. Epub 2013 Apr 3 doi: 10.1016/j.jprot.2013.03.024. PMID: 23563203
Tricyclic antidepressant poisoning : cardiovascular toxicity.
Thanacoody HK, Thomas SH
Toxicol Rev 2005;24(3):205-14. doi: 10.2165/00139709-200524030-00013. PMID: 16390222

Prognosis

Electrocardiographic Predictors of Atrial Fibrillation.
Chousou PA, Chattopadhyay R, Tsampasian V, Vassiliou VS, Pugh PJ
Med Sci (Basel) 2023 Apr 7;11(2) doi: 10.3390/medsci11020030. PMID: 37092499Free PMC Article
Overlapping obesity-related glomerulopathy and immunoglobulin A nephropathy: clinical and pathologic characteristics and prognosis.
Zhang J, Wang Y, Liu Z, Huang B, Wang X, Xie M, Yu D, Guo R, Wang P
Clin Exp Nephrol 2021 Aug;25(8):865-874. Epub 2021 Apr 2 doi: 10.1007/s10157-021-02045-4. PMID: 33811270
Diagnostic and prognostic role of electrocardiogram in acute myocarditis: A comprehensive review.
Buttà C, Zappia L, Laterra G, Roberto M
Ann Noninvasive Electrocardiol 2020 May;25(3) Epub 2019 Nov 28 doi: 10.1111/anec.12726. PMID: 31778001Free PMC Article
Prognostic significance of abnormal P wave morphology and PR-segment displacement after ST-elevation myocardial infarction.
Lu ML, Nwakile C, Bhalla V, De Venecia T, Shah M, Figueredo VM
Int J Cardiol 2015 Oct 15;197:216-21. Epub 2015 Jun 24 doi: 10.1016/j.ijcard.2015.06.055. PMID: 26148766
The aging electrocardiogram.
Jones J, Srodulski ZM, Romisher S
Am J Emerg Med 1990 May;8(3):240-5. doi: 10.1016/0735-6757(90)90331-s. PMID: 2184809

Clinical prediction guides

Prognostic significance of quantitative electrocardiographic parameters in patients with non-high-risk pulmonary embolism.
Yan XX, Zhang HD, Peng FH, Ding L, Mi LJ, Zhang AK, Hua L, Tang M
Eur J Intern Med 2024 Feb;120:46-51. Epub 2023 Sep 9 doi: 10.1016/j.ejim.2023.08.028. PMID: 37679281
Electrocardiographic Predictors of Atrial Fibrillation.
Chousou PA, Chattopadhyay R, Tsampasian V, Vassiliou VS, Pugh PJ
Med Sci (Basel) 2023 Apr 7;11(2) doi: 10.3390/medsci11020030. PMID: 37092499Free PMC Article
Hippocampal subfield morphology in regular hemodialysis patients.
Chen HJ, Qiu J, Qi Y, Fu L, Fu Q, Wu W, Dai G, Chen F
Nephrol Dial Transplant 2023 Mar 31;38(4):992-1001. doi: 10.1093/ndt/gfac263. PMID: 36124763Free PMC Article
Transverse myelitis associated with primary biliary cirrhosis: clinical, laboratory, and neuroradiological features.
Zhao M, Zhang M, Zhou S, Shi B, Wei Y, Huang F, Wang J, Huang J, Qiao L
Int J Neurosci 2022 Apr;132(4):370-377. Epub 2020 Sep 7 doi: 10.1080/00207454.2020.1815735. PMID: 32842840
Evaluation of anemia and serum iPTH, calcium, and phosphorus in patients with primary glomerulonephritis.
Li Y, Zhang W, Ren H, Wang W, Shi H, Li X, Chen X, Shen P, Wu X, Xie J, Chen N
Contrib Nephrol 2013;181:31-40. Epub 2013 May 8 doi: 10.1159/000348636. PMID: 23689565

Recent systematic reviews

ECG predictors of AF: A systematic review (predicting AF in ischaemic stroke-PrAFIS).
Berry-Noronha A, Bonavia L, Song E, Grose D, Johnson D, Maylin E, Oqueli E, Sahathevan R
Clin Neurol Neurosurg 2024 Feb;237:108164. Epub 2024 Feb 11 doi: 10.1016/j.clineuro.2024.108164. PMID: 38377651
Electrocardiographic Predictors of Atrial Fibrillation.
Chousou PA, Chattopadhyay R, Tsampasian V, Vassiliou VS, Pugh PJ
Med Sci (Basel) 2023 Apr 7;11(2) doi: 10.3390/medsci11020030. PMID: 37092499Free PMC Article
Nerve abnormalities in lumbar disc herniation: A systematic review and meta-analysis of diffusion tensor imaging.
Wang N, Sun D, Zhang X, Xi Z, Li J, Xie L
PLoS One 2022;17(12):e0279499. Epub 2022 Dec 27 doi: 10.1371/journal.pone.0279499. PMID: 36574380Free PMC Article

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