U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal oral physiology

MedGen UID:
1631824
•Concept ID:
C4703551
•
Disease or Syndrome
HPO: HP:0031815

Definition

A functional anomaly of the mouth (which is also known as the oral cavity). [from HPO]

Professional guidelines

PubMed

Diagnosis and Management of Multiple Myeloma: A Review.
Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, Tuazon S, Gopal AK, Libby EN
JAMA 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003. PMID: 35103762
Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management.
Tefferi A, Barbui T
Am J Hematol 2020 Dec;95(12):1599-1613. Epub 2020 Oct 23 doi: 10.1002/ajh.26008. PMID: 32974939
Diagnosis and treatment of temporomandibular disorders.
Gauer RL, Semidey MJ
Am Fam Physician 2015 Mar 15;91(6):378-86. PMID: 25822556

Recent clinical studies

Etiology

Hypophosphatasia: oral cavity and dental disorders.
Bloch-Zupan A, Vaysse F
Arch Pediatr 2017 May;24(5S2):5S80-5S84. doi: 10.1016/S0929-693X(18)30020-4. PMID: 29405938
Meier-Gorlin syndrome.
de Munnik SA, Hoefsloot EH, Roukema J, Schoots J, Knoers NV, Brunner HG, Jackson AP, Bongers EM
Orphanet J Rare Dis 2015 Sep 17;10:114. doi: 10.1186/s13023-015-0322-x. PMID: 26381604Free PMC Article
Preterm infants--odontological aspects.
Rythén M
Swed Dent J Suppl 2012;(224):2p preceding i-vi, 1-106. PMID: 22755470
Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.
Barron MJ, McDonnell ST, Mackie I, Dixon MJ
Orphanet J Rare Dis 2008 Nov 20;3:31. doi: 10.1186/1750-1172-3-31. PMID: 19021896Free PMC Article
Epilepsy and pregnancy.
O'Brien MD, Gilmour-White S
BMJ 1993 Aug 21;307(6902):492-5. doi: 10.1136/bmj.307.6902.492. PMID: 8400940Free PMC Article

Diagnosis

The ontogeny of Robin sequence.
Logjes RJH, Breugem CC, Van Haaften G, Paes EC, Sperber GH, van den Boogaard MH, Farlie PG
Am J Med Genet A 2018 Jun;176(6):1349-1368. Epub 2018 Apr 25 doi: 10.1002/ajmg.a.38718. PMID: 29696787
Hypophosphatasia: oral cavity and dental disorders.
Bloch-Zupan A, Vaysse F
Arch Pediatr 2017 May;24(5S2):5S80-5S84. doi: 10.1016/S0929-693X(18)30020-4. PMID: 29405938
Meier-Gorlin syndrome.
de Munnik SA, Hoefsloot EH, Roukema J, Schoots J, Knoers NV, Brunner HG, Jackson AP, Bongers EM
Orphanet J Rare Dis 2015 Sep 17;10:114. doi: 10.1186/s13023-015-0322-x. PMID: 26381604Free PMC Article
Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.
Barron MJ, McDonnell ST, Mackie I, Dixon MJ
Orphanet J Rare Dis 2008 Nov 20;3:31. doi: 10.1186/1750-1172-3-31. PMID: 19021896Free PMC Article
KBG syndrome.
Brancati F, Sarkozy A, Dallapiccola B
Orphanet J Rare Dis 2006 Dec 12;1:50. doi: 10.1186/1750-1172-1-50. PMID: 17163996Free PMC Article

Therapy

Gene-environment interaction in molar-incisor hypomineralization.
Bezamat M, Souza JF, Silva FMF, Corrêa EG, Fatturi AL, Brancher JA, Carvalho FM, Cavallari T, Bertolazo L, Machado-Souza C, Koruyucu M, Bayram M, Racic A, Harrison BM, Sweat YY, Letra A, Studen-Pavlovich D, Seymen F, Amendt B, Werneck RI, Costa MC, Modesto A, Vieira AR
PLoS One 2021;16(1):e0241898. Epub 2021 Jan 6 doi: 10.1371/journal.pone.0241898. PMID: 33406080Free PMC Article
Protein-mediated enamel mineralization.
Moradian-Oldak J
Front Biosci (Landmark Ed) 2012 Jun 1;17(6):1996-2023. doi: 10.2741/4034. PMID: 22652761Free PMC Article
Epilepsy and pregnancy.
O'Brien MD, Gilmour-White S
BMJ 1993 Aug 21;307(6902):492-5. doi: 10.1136/bmj.307.6902.492. PMID: 8400940Free PMC Article
Adolescent menstrual irregularity.
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175
Amenorrhea.
Marchant DJ
Clin Obstet Gynecol 1969 Sep;12(3):693-707. doi: 10.1097/00003081-196909000-00010. PMID: 5388335

Prognosis

KDF1 Novel Variant Causes Unique Dental and Oral Epithelial Defects.
Yu M, Liu H, Liu Y, Zheng J, Wu J, Sun K, Feng H, Liu H, Han D
Int J Mol Sci 2022 Oct 18;23(20) doi: 10.3390/ijms232012465. PMID: 36293320Free PMC Article
A Review of the Functions of Matrix Vesicles in Periodontal Tissues.
Yi G, Ma Y, Chen Y, Yang X, Yang B, Tian W
Stem Cells Dev 2021 Feb;30(4):165-176. Epub 2021 Feb 8 doi: 10.1089/scd.2020.0155. PMID: 33349125
Abnormal cytology in oropharyngeal brushings and in oral rinses is not associated with HPV infection: The OHMAR study.
Benevolo M, Rollo F, Giuliani M, Pichi B, Latini A, Pellini R, Vescio MF, Morrone A, Cristaudo A, Donà MG
Cancer Cytopathol 2020 Sep;128(9):648-655. Epub 2020 Jun 2 doi: 10.1002/cncy.22295. PMID: 32485093
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Clinical and molecular features of Joubert syndrome and related disorders.
Parisi MA
Am J Med Genet C Semin Med Genet 2009 Nov 15;151C(4):326-40. doi: 10.1002/ajmg.c.30229. PMID: 19876931Free PMC Article

Clinical prediction guides

A Review of Dentinogenesis Imperfecta and Primary Dentin Disorders in Dogs.
Mack Wilson J, Bell C, Queck K, Scott K
J Vet Dent 2022 Dec;39(4):376-390. Epub 2022 Sep 15 doi: 10.1177/08987564221123419. PMID: 36113440
Abnormal cytology in oropharyngeal brushings and in oral rinses is not associated with HPV infection: The OHMAR study.
Benevolo M, Rollo F, Giuliani M, Pichi B, Latini A, Pellini R, Vescio MF, Morrone A, Cristaudo A, Donà MG
Cancer Cytopathol 2020 Sep;128(9):648-655. Epub 2020 Jun 2 doi: 10.1002/cncy.22295. PMID: 32485093
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Oral manifestations in patients with familial adenomatous polyposis: A systematic review and meta-analysis.
Almeida FT, Pachêco-Pereira C, Porporatti AL, Flores-Mir C, Leite AF, De Luca Canto G, Guerra EN
J Gastroenterol Hepatol 2016 Mar;31(3):527-40. doi: 10.1111/jgh.13149. PMID: 26331960
KBG syndrome.
Brancati F, Sarkozy A, Dallapiccola B
Orphanet J Rare Dis 2006 Dec 12;1:50. doi: 10.1186/1750-1172-1-50. PMID: 17163996Free PMC Article

Recent systematic reviews

Gastroschisis: a systematic review of diagnosis, prognosis and treatment.
Ferreira RG, Mendonça CR, Gonçalves Ramos LL, de Abreu Tacon FS, Naves do Amaral W, Ruano R
J Matern Fetal Neonatal Med 2022 Dec;35(25):6199-6212. Epub 2021 Apr 25 doi: 10.1080/14767058.2021.1909563. PMID: 33899664
Advances in Pathogenesis of Sjögren's Syndrome.
Tian Y, Yang H, Liu N, Li Y, Chen J
J Immunol Res 2021;2021:5928232. Epub 2021 Oct 7 doi: 10.1155/2021/5928232. PMID: 34660815Free PMC Article
Down syndrome as a cause of abnormalities in the craniofacial region: A systematic literature review.
Kaczorowska N, Kaczorowski K, Laskowska J, Mikulewicz M
Adv Clin Exp Med 2019 Nov;28(11):1587-1592. doi: 10.17219/acem/112785. PMID: 31778604
Non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency revisited: an update with a special focus on adolescent and adult women.
Carmina E, Dewailly D, Escobar-Morreale HF, Kelestimur F, Moran C, Oberfield S, Witchel SF, Azziz R
Hum Reprod Update 2017 Sep 1;23(5):580-599. doi: 10.1093/humupd/dmx014. PMID: 28582566
Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review.
Layton AM, Eady EA, Whitehouse H, Del Rosso JQ, Fedorowicz Z, van Zuuren EJ
Am J Clin Dermatol 2017 Apr;18(2):169-191. doi: 10.1007/s40257-016-0245-x. PMID: 28155090Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...