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ROS1 Gene Inversion

MedGen UID:
Concept ID:
Cell or Molecular Dysfunction
Synonyms: c-ros-1 Gene Inversion; MCF3 Gene Inversion; ROS Gene Inversion; ROS Proto-Oncogene 1, Receptor Tyrosine Kinase Gene Inversion; ROS1 Inversion; ROS1 Inversion Mutation


A genetic rearrangement that refers to any inversion involving the ROS1 gene. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVROS1 Gene Inversion

Recent clinical studies


Amatu A, Somaschini A, Cerea G, Bosotti R, Valtorta E, Buonandi P, Marrapese G, Veronese S, Luo D, Hornby Z, Multani P, Murphy D, Shoemaker R, Lauricella C, Giannetta L, Maiolani M, Vanzulli A, Ardini E, Galvani A, Isacchi A, Sartore-Bianchi A, Siena S
Br J Cancer 2015 Dec 22;113(12):1730-4. Epub 2015 Dec 3 doi: 10.1038/bjc.2015.401. PMID: 26633560Free PMC Article

Clinical prediction guides

Choi PS, Meyerson M
Nat Commun 2014 Apr 24;5:3728. doi: 10.1038/ncomms4728. PMID: 24759083Free PMC Article

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