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Central Nervous System B-Cell Non-Hodgkin Lymphoma

MedGen UID:
1632151
Concept ID:
C4688312
Neoplastic Process
Synonyms: B-Cell Primary Central Nervous System Non-Hodgkin Lymphoma; Primary Central Nervous System B-Cell Non-Hodgkin's Lymphoma

Definition

A B-cell non-Hodgkin lymphoma that arises from the brain, meninges, or spinal cord. [from NCI]

Professional guidelines

PubMed

Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012Free PMC Article
Crombie J, LaCasce A
Blood 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099. PMID: 33171490
Moleti ML, Testi AM, Foà R
Br J Haematol 2020 Jun;189(5):826-843. Epub 2020 Mar 6 doi: 10.1111/bjh.16461. PMID: 32141616

Recent clinical studies

Etiology

Melchardt T, Egle A, Greil R
ESMO Open 2023 Feb;8(1):100750. Epub 2023 Jan 10 doi: 10.1016/j.esmoop.2022.100750. PMID: 36634531Free PMC Article
Wilson MR, Bobillo S, Cwynarski K
Hematology Am Soc Hematol Educ Program 2022 Dec 9;2022(1):138-145. doi: 10.1182/hematology.2022000331. PMID: 36485105Free PMC Article
Eyre TA, Savage KJ, Cheah CY, El-Galaly TC, Lewis KL, McKay P, Wilson MR, Evens AM, Bobillo S, Villa D, Maurer MJ, Cwynarski K, Ferreri AJM
Lancet Oncol 2022 Sep;23(9):e416-e426. doi: 10.1016/S1470-2045(22)00371-0. PMID: 36055310
Moleti ML, Testi AM, Foà R
Br J Haematol 2020 Jun;189(5):826-843. Epub 2020 Mar 6 doi: 10.1111/bjh.16461. PMID: 32141616
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article

Diagnosis

Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246Free PMC Article
Calimeri T, Steffanoni S, Gagliardi F, Chiara A, Ferreri AJM
ESMO Open 2021 Aug;6(4):100213. Epub 2021 Jul 13 doi: 10.1016/j.esmoop.2021.100213. PMID: 34271311Free PMC Article
Moleti ML, Testi AM, Foà R
Br J Haematol 2020 Jun;189(5):826-843. Epub 2020 Mar 6 doi: 10.1111/bjh.16461. PMID: 32141616
Grommes C, Rubenstein JL, DeAngelis LM, Ferreri AJM, Batchelor TT
Neuro Oncol 2019 Feb 19;21(3):296-305. doi: 10.1093/neuonc/noy192. PMID: 30418592Free PMC Article
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article

Therapy

Melchardt T, Egle A, Greil R
ESMO Open 2023 Feb;8(1):100750. Epub 2023 Jan 10 doi: 10.1016/j.esmoop.2022.100750. PMID: 36634531Free PMC Article
Wilson MR, Bobillo S, Cwynarski K
Hematology Am Soc Hematol Educ Program 2022 Dec 9;2022(1):138-145. doi: 10.1182/hematology.2022000331. PMID: 36485105Free PMC Article
Eyre TA, Savage KJ, Cheah CY, El-Galaly TC, Lewis KL, McKay P, Wilson MR, Evens AM, Bobillo S, Villa D, Maurer MJ, Cwynarski K, Ferreri AJM
Lancet Oncol 2022 Sep;23(9):e416-e426. doi: 10.1016/S1470-2045(22)00371-0. PMID: 36055310
Calimeri T, Steffanoni S, Gagliardi F, Chiara A, Ferreri AJM
ESMO Open 2021 Aug;6(4):100213. Epub 2021 Jul 13 doi: 10.1016/j.esmoop.2021.100213. PMID: 34271311Free PMC Article
Crombie J, LaCasce A
Blood 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099. PMID: 33171490

Prognosis

Hernández-Verdin I, Kirasic E, Wienand K, Mokhtari K, Eimer S, Loiseau H, Rousseau A, Paillassa J, Ahle G, Lerintiu F, Uro-Coste E, Oberic L, Figarella-Branger D, Chinot O, Gauchotte G, Taillandier L, Marolleau JP, Polivka M, Adam C, Ursu R, Schmitt A, Barillot N, Nichelli L, Lozano-Sánchez F, Ibañez-Juliá MJ, Peyre M, Mathon B, Abada Y, Charlotte F, Davi F, Stewart C, de Reyniès A, Choquet S, Soussain C, Houillier C, Chapuy B, Hoang-Xuan K, Alentorn A
Ann Oncol 2023 Feb;34(2):186-199. Epub 2022 Nov 17 doi: 10.1016/j.annonc.2022.11.002. PMID: 36402300
Crombie J, LaCasce A
Blood 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099. PMID: 33171490
Moleti ML, Testi AM, Foà R
Br J Haematol 2020 Jun;189(5):826-843. Epub 2020 Mar 6 doi: 10.1111/bjh.16461. PMID: 32141616
Ponzoni M, Campo E, Nakamura S
Blood 2018 Oct 11;132(15):1561-1567. Epub 2018 Aug 15 doi: 10.1182/blood-2017-04-737445. PMID: 30111607
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article

Clinical prediction guides

Alderuccio JP, Nayak L, Cwynarski K
Blood 2023 Nov 23;142(21):1771-1783. doi: 10.1182/blood.2023020168. PMID: 37702537Free PMC Article
Scordo M, Wang TP, Ahn KW, Chen Y, Ahmed S, Awan FT, Beitinjaneh A, Chen A, Chow VA, Dholaria B, Epperla N, Farooq U, Ghosh N, Grover N, Hamad N, Hildebrandt GC, Holmberg L, Hong S, Inwards DJ, Jimenez-Jimenez A, Karmali R, Kenkre VP, Khimani F, Klyuchnikov E, Krem MM, Munshi PN, Nieto Y, Prestidge T, Ramakrishnan Geethakumari P, Rezvani AR, Riedell PA, Seo S, Shah NN, Solh M, Yared JA, Kharfan-Dabaja MA, Herrera A, Hamadani M, Sauter CS
JAMA Oncol 2021 Jul 1;7(7):993-1003. doi: 10.1001/jamaoncol.2021.1074. PMID: 33956047Free PMC Article
Ponzoni M, Campo E, Nakamura S
Blood 2018 Oct 11;132(15):1561-1567. Epub 2018 Aug 15 doi: 10.1182/blood-2017-04-737445. PMID: 30111607
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article
Ferreri AJ, Cwynarski K, Pulczynski E, Ponzoni M, Deckert M, Politi LS, Torri V, Fox CP, Rosée PL, Schorb E, Ambrosetti A, Roth A, Hemmaway C, Ferrari A, Linton KM, Rudà R, Binder M, Pukrop T, Balzarotti M, Fabbri A, Johnson P, Gørløv JS, Hess G, Panse J, Pisani F, Tucci A, Stilgenbauer S, Hertenstein B, Keller U, Krause SW, Levis A, Schmoll HJ, Cavalli F, Finke J, Reni M, Zucca E, Illerhaus G; International Extranodal Lymphoma Study Group (IELSG)
Lancet Haematol 2016 May;3(5):e217-27. Epub 2016 Apr 6 doi: 10.1016/S2352-3026(16)00036-3. PMID: 27132696

Recent systematic reviews

Cook MR, Dorris CS, Makambi KH, Luo Y, Munshi PN, Donato M, Rowley S, Saad A, Goy A, Dunleavy K, Ali A
Blood Adv 2023 Jan 10;7(1):32-39. doi: 10.1182/bloodadvances.2022008525. PMID: 36260735Free PMC Article
Farrall AL, Smith JR
Surv Ophthalmol 2020 Sep-Oct;65(5):548-561. Epub 2020 Feb 11 doi: 10.1016/j.survophthal.2020.02.001. PMID: 32057762
Schmitt AM, Herbrand AK, Fox CP, Bakunina K, Bromberg JEC, Cwynarski K, Doorduijn JK, Ferreri AJM, Illerhaus G, Issa S, Schorb E, Zucca E, Hemkens LG, Schandelmaier S, Kasenda B
Hematol Oncol 2019 Dec;37(5):548-557. Epub 2019 Oct 9 doi: 10.1002/hon.2666. PMID: 31418878
Ghose A, Elias HK, Guha G, Yellu M, Kundu R, Latif T
Clin Lymphoma Myeloma Leuk 2015 Aug;15(8):451-7. Epub 2015 Mar 5 doi: 10.1016/j.clml.2015.02.026. PMID: 25816933
Zhang J, Chen B, Xu X
Leuk Lymphoma 2014 Mar;55(3):509-14. Epub 2013 Jul 29 doi: 10.3109/10428194.2013.811239. PMID: 23741977

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