U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Idiopathic panuveitis

MedGen UID:
1633708
Concept ID:
C4707884
Disease or Syndrome
Synonym: idiopathic panuveitis
SNOMED CT: Idiopathic panuveitis (766933000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0017258
Orphanet: ORPHA280921

Definition

A rare inflammatory eye disease of unknown aetiology characterised by generalised inflammation of the uvea (iris, ciliary body, choroid), retina and vitreous with consequent ciliary spasm and posterior synechiae formation, leading to acute or chronic, unilateral or bilateral visual impairment and ocular discomfort or pain. Patients present an increased risk of development of cataracts, secondary glaucoma, cystoid macular oedema and/or retinal detachment. It could potentially result in vision loss. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIdiopathic panuveitis

Professional guidelines

PubMed

Chen TS, Tsang WM, Enkh-Amgalan I, Hwang YS
Eye (Lond) 2020 Nov;34(11):2098-2105. Epub 2020 Jul 6 doi: 10.1038/s41433-020-1066-y. PMID: 32632297Free PMC Article
Muñoz-Gallego A, Barral E, Enríquez E, Tejada P, Barceló A, de Inocencio J
Int Ophthalmol 2017 Jun;37(3):719-725. Epub 2016 Jul 18 doi: 10.1007/s10792-016-0293-5. PMID: 27432171
Giuliari GP, Chang PY, Thakuria P, Hinkle DM, Foster CS
Eye (Lond) 2010 Jan;24(1):7-13. Epub 2010 Jan 8 doi: 10.1038/eye.2009.294. PMID: 20057512

Recent clinical studies

Etiology

Chen TS, Tsang WM, Enkh-Amgalan I, Hwang YS
Eye (Lond) 2020 Nov;34(11):2098-2105. Epub 2020 Jul 6 doi: 10.1038/s41433-020-1066-y. PMID: 32632297Free PMC Article
Mesquida M, Molins B, Llorenç V, Hernández MV, Espinosa G, Sainz de la Maza M, Adán A
Retina 2018 Jul;38(7):1361-1370. doi: 10.1097/IAE.0000000000001690. PMID: 28520640
Muñoz-Gallego A, Barral E, Enríquez E, Tejada P, Barceló A, de Inocencio J
Int Ophthalmol 2017 Jun;37(3):719-725. Epub 2016 Jul 18 doi: 10.1007/s10792-016-0293-5. PMID: 27432171
Siak J, Jansen A, Waduthantri S, Teoh CS, Jap A, Chee SP
Ocul Immunol Inflamm 2017;25(sup1):S81-S93. Epub 2016 Jul 15 doi: 10.1080/09273948.2016.1188968. PMID: 27419535
Karampelas M, Sim DA, Keane PA, Zarranz-Ventura J, Patel PJ, Tufail A, Westcott M, Lee R, Pavesio CE
Graefes Arch Clin Exp Ophthalmol 2013 Aug;251(8):2029-36. Epub 2013 Mar 28 doi: 10.1007/s00417-013-2330-7. PMID: 23532454

Diagnosis

Kongwattananon W, Grasic D, Lin H, Oyeniran E, Sen HN, Kodati S
Retina 2022 Jun 1;42(6):1047-1056. doi: 10.1097/IAE.0000000000003420. PMID: 35067607Free PMC Article
Mesquida M, Molins B, Llorenç V, Hernández MV, Espinosa G, Sainz de la Maza M, Adán A
Retina 2018 Jul;38(7):1361-1370. doi: 10.1097/IAE.0000000000001690. PMID: 28520640
Muñoz-Gallego A, Barral E, Enríquez E, Tejada P, Barceló A, de Inocencio J
Int Ophthalmol 2017 Jun;37(3):719-725. Epub 2016 Jul 18 doi: 10.1007/s10792-016-0293-5. PMID: 27432171
Karampelas M, Sim DA, Keane PA, Zarranz-Ventura J, Patel PJ, Tufail A, Westcott M, Lee R, Pavesio CE
Graefes Arch Clin Exp Ophthalmol 2013 Aug;251(8):2029-36. Epub 2013 Mar 28 doi: 10.1007/s00417-013-2330-7. PMID: 23532454
Merrill PT, Kim J, Cox TA, Betor CC, McCallum RM, Jaffe GJ
Curr Eye Res 1997 Sep;16(9):865-74. doi: 10.1076/ceyr.16.9.865.5048. PMID: 9288447

Therapy

Chen TS, Tsang WM, Enkh-Amgalan I, Hwang YS
Eye (Lond) 2020 Nov;34(11):2098-2105. Epub 2020 Jul 6 doi: 10.1038/s41433-020-1066-y. PMID: 32632297Free PMC Article
Mesquida M, Molins B, Llorenç V, Hernández MV, Espinosa G, Sainz de la Maza M, Adán A
Retina 2018 Jul;38(7):1361-1370. doi: 10.1097/IAE.0000000000001690. PMID: 28520640
Muñoz-Gallego A, Barral E, Enríquez E, Tejada P, Barceló A, de Inocencio J
Int Ophthalmol 2017 Jun;37(3):719-725. Epub 2016 Jul 18 doi: 10.1007/s10792-016-0293-5. PMID: 27432171
Mesquida M, Molins B, Llorenç V, Sainz de la Maza M, Adán A
Ophthalmology 2014 Dec;121(12):2380-6. Epub 2014 Sep 6 doi: 10.1016/j.ophtha.2014.06.050. PMID: 25204610
Yeh S, Wroblewski K, Buggage R, Li Z, Kurup SK, Sen HN, Dahr S, Sran P, Reed GF, Robinson R, Ragheb JA, Waldmann TA, Nussenblatt RB
J Autoimmun 2008 Sep;31(2):91-7. Epub 2008 Jun 20 doi: 10.1016/j.jaut.2008.05.001. PMID: 18571896Free PMC Article

Prognosis

Chang PY
Digit J Ophthalmol 2022;28(4):119-125. Epub 2022 Dec 28 doi: 10.5693/djo.02.2022.10.002. PMID: 36660185Free PMC Article
Mesquida M, Molins B, Llorenç V, Hernández MV, Espinosa G, Sainz de la Maza M, Adán A
Retina 2018 Jul;38(7):1361-1370. doi: 10.1097/IAE.0000000000001690. PMID: 28520640
Roy R, Saurabh K, Bansal A, Kumar A, Majumdar AK, Paul SS
Indian J Ophthalmol 2017 Apr;65(4):295-300. doi: 10.4103/ijo.IJO_262_16. PMID: 28513493Free PMC Article
Muñoz-Gallego A, Barral E, Enríquez E, Tejada P, Barceló A, de Inocencio J
Int Ophthalmol 2017 Jun;37(3):719-725. Epub 2016 Jul 18 doi: 10.1007/s10792-016-0293-5. PMID: 27432171
Arcinue CA, Cerón OM, Foster CS
J Ocul Pharmacol Ther 2013 Jun;29(5):501-7. Epub 2013 Jan 8 doi: 10.1089/jop.2012.0180. PMID: 23297752

Clinical prediction guides

Mesquida M, Molins B, Llorenç V, Sainz de la Maza M, Adán A
Ophthalmology 2014 Dec;121(12):2380-6. Epub 2014 Sep 6 doi: 10.1016/j.ophtha.2014.06.050. PMID: 25204610
Adán A, Mesquida M, Llorenç V, Espinosa G, Molins B, Hernández MV, Pelegrín L
Graefes Arch Clin Exp Ophthalmol 2013 Nov;251(11):2627-32. Epub 2013 Jul 27 doi: 10.1007/s00417-013-2436-y. PMID: 23893042
Karampelas M, Sim DA, Keane PA, Zarranz-Ventura J, Patel PJ, Tufail A, Westcott M, Lee R, Pavesio CE
Graefes Arch Clin Exp Ophthalmol 2013 Aug;251(8):2029-36. Epub 2013 Mar 28 doi: 10.1007/s00417-013-2330-7. PMID: 23532454
Arcinue CA, Cerón OM, Foster CS
J Ocul Pharmacol Ther 2013 Jun;29(5):501-7. Epub 2013 Jan 8 doi: 10.1089/jop.2012.0180. PMID: 23297752
Jaffe GJ, Ben-Nun J, Guo H, Dunn JP, Ashton P
Ophthalmology 2000 Nov;107(11):2024-33. doi: 10.1016/s0161-6420(00)00466-8. PMID: 11054326

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...