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Adenomatous polyp of colon

MedGen UID:
163407
Concept ID:
C0850572
Neoplastic Process
Synonym: Adenomatous colon polyp
SNOMED CT: Adenomatous polyp of colon (428054006)
 
Monarch Initiative: MONDO:0006498

Definition

A polypoid adenoma that arises from and protrudes into the lumen of the colon. Epithelial dysplasia is always present. According to the architectural pattern it is classified as tubular, tubulovillous, or villous. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdenomatous polyp of colon

Professional guidelines

PubMed

Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Ferlitsch M, Moss A, Hassan C, Bhandari P, Dumonceau JM, Paspatis G, Jover R, Langner C, Bronzwaer M, Nalankilli K, Fockens P, Hazzan R, Gralnek IM, Gschwantler M, Waldmann E, Jeschek P, Penz D, Heresbach D, Moons L, Lemmers A, Paraskeva K, Pohl J, Ponchon T, Regula J, Repici A, Rutter MD, Burgess NG, Bourke MJ
Endoscopy 2017 Mar;49(3):270-297. Epub 2017 Feb 17 doi: 10.1055/s-0043-102569. PMID: 28212588
Cappell MS
Gastroenterol Clin North Am 2008 Mar;37(1):1-24, v. doi: 10.1016/j.gtc.2007.12.002. PMID: 18313537

Recent clinical studies

Etiology

Waldum H, Fossmark R
Int J Mol Sci 2021 Jun 18;22(12) doi: 10.3390/ijms22126548. PMID: 34207192Free PMC Article
Hao Y, Wang Y, Qi M, He X, Zhu Y, Hong J
Gut Liver 2020 Jul 15;14(4):399-411. doi: 10.5009/gnl19097. PMID: 31547641Free PMC Article
Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Ferlitsch M, Moss A, Hassan C, Bhandari P, Dumonceau JM, Paspatis G, Jover R, Langner C, Bronzwaer M, Nalankilli K, Fockens P, Hazzan R, Gralnek IM, Gschwantler M, Waldmann E, Jeschek P, Penz D, Heresbach D, Moons L, Lemmers A, Paraskeva K, Pohl J, Ponchon T, Regula J, Repici A, Rutter MD, Burgess NG, Bourke MJ
Endoscopy 2017 Mar;49(3):270-297. Epub 2017 Feb 17 doi: 10.1055/s-0043-102569. PMID: 28212588
Zauber AG, Winawer SJ, O'Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, Shi W, Bond JH, Schapiro M, Panish JF, Stewart ET, Waye JD
N Engl J Med 2012 Feb 23;366(8):687-96. doi: 10.1056/NEJMoa1100370. PMID: 22356322Free PMC Article

Diagnosis

Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Murakami T, Sakamoto N, Nagahara A
J Gastroenterol Hepatol 2019 Oct;34(10):1685-1695. Epub 2019 Jun 30 doi: 10.1111/jgh.14752. PMID: 31158302
Ferlitsch M, Moss A, Hassan C, Bhandari P, Dumonceau JM, Paspatis G, Jover R, Langner C, Bronzwaer M, Nalankilli K, Fockens P, Hazzan R, Gralnek IM, Gschwantler M, Waldmann E, Jeschek P, Penz D, Heresbach D, Moons L, Lemmers A, Paraskeva K, Pohl J, Ponchon T, Regula J, Repici A, Rutter MD, Burgess NG, Bourke MJ
Endoscopy 2017 Mar;49(3):270-297. Epub 2017 Feb 17 doi: 10.1055/s-0043-102569. PMID: 28212588
Jochem C, Leitzmann M
Recent Results Cancer Res 2016;208:17-41. doi: 10.1007/978-3-319-42542-9_2. PMID: 27909900

Therapy

Rondonotti E, Hassan C, Tamanini G, Antonelli G, Andrisani G, Leonetti G, Paggi S, Amato A, Scardino G, Di Paolo D, Mandelli G, Lenoci N, Terreni N, Andrealli A, Maselli R, Spadaccini M, Galtieri PA, Correale L, Repici A, Di Matteo FM, Ambrosiani L, Filippi E, Sharma P, Radaelli F
Endoscopy 2023 Jan;55(1):14-22. Epub 2022 May 13 doi: 10.1055/a-1852-0330. PMID: 35562098
Joh HK, Lee DH, Hur J, Nimptsch K, Chang Y, Joung H, Zhang X, Rezende LFM, Lee JE, Ng K, Yuan C, Tabung FK, Meyerhardt JA, Chan AT, Pischon T, Song M, Fuchs CS, Willett WC, Cao Y, Ogino S, Giovannucci E, Wu K
Gastroenterology 2021 Jul;161(1):128-142.e20. Epub 2021 Mar 19 doi: 10.1053/j.gastro.2021.03.028. PMID: 33753105Free PMC Article
Wakeman C, Keenan J, Eteuati J, Hollington P, Eglinton T, Frizelle F
ANZ J Surg 2017 Dec;87(12):E228-E232. Epub 2015 Dec 21 doi: 10.1111/ans.13392. PMID: 26686322
Aarons CB, Shanmugan S, Bleier JI
World J Gastroenterol 2014 Nov 21;20(43):16178-83. doi: 10.3748/wjg.v20.i43.16178. PMID: 25473171Free PMC Article
Greenwald P
Cancer 1992 Sep 1;70(5 Suppl):1206-15. doi: 10.1002/1097-0142(19920901)70:3+<1206::aid-cncr2820701504>3.0.co;2-j. PMID: 1511368

Prognosis

Hao Y, Wang Y, Qi M, He X, Zhu Y, Hong J
Gut Liver 2020 Jul 15;14(4):399-411. doi: 10.5009/gnl19097. PMID: 31547641Free PMC Article
Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Meijers WC, Maglione M, Bakker SJL, Oberhuber R, Kieneker LM, de Jong S, Haubner BJ, Nagengast WB, Lyon AR, van der Vegt B, van Veldhuisen DJ, Westenbrink BD, van der Meer P, Silljé HHW, de Boer RA
Circulation 2018 Aug 14;138(7):678-691. doi: 10.1161/CIRCULATIONAHA.117.030816. PMID: 29459363
Zauber AG, Winawer SJ, O'Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, Shi W, Bond JH, Schapiro M, Panish JF, Stewart ET, Waye JD
N Engl J Med 2012 Feb 23;366(8):687-96. doi: 10.1056/NEJMoa1100370. PMID: 22356322Free PMC Article
Ponz de Leon M, Di Gregorio C
Dig Liver Dis 2001 May;33(4):372-88. doi: 10.1016/s1590-8658(01)80095-5. PMID: 11432519

Clinical prediction guides

Ishibashi F, Suzuki S, Nagai M, Mochida K, Morishita T
Dig Endosc 2023 Mar;35(3):278-286. Epub 2022 Sep 6 doi: 10.1111/den.14420. PMID: 35962754
Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Meijers WC, Maglione M, Bakker SJL, Oberhuber R, Kieneker LM, de Jong S, Haubner BJ, Nagengast WB, Lyon AR, van der Vegt B, van Veldhuisen DJ, Westenbrink BD, van der Meer P, Silljé HHW, de Boer RA
Circulation 2018 Aug 14;138(7):678-691. doi: 10.1161/CIRCULATIONAHA.117.030816. PMID: 29459363
Zauber AG, Winawer SJ, O'Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, Shi W, Bond JH, Schapiro M, Panish JF, Stewart ET, Waye JD
N Engl J Med 2012 Feb 23;366(8):687-96. doi: 10.1056/NEJMoa1100370. PMID: 22356322Free PMC Article
Lal G, Gallinger S
Semin Surg Oncol 2000 Jun;18(4):314-23. doi: 10.1002/(sici)1098-2388(200006)18:4<314::aid-ssu6>3.0.co;2-9. PMID: 10805953

Recent systematic reviews

Hembree AE, Scherl E
Dis Colon Rectum 2022 Dec 1;65(S1):S85-S91. Epub 2022 Aug 25 doi: 10.1097/DCR.0000000000002593. PMID: 36399769
Emile SH, Khan SM, Silva-Alvarenga E, Garoufalia Z, Wexner SD
Tech Coloproctol 2022 Sep;26(9):691-705. Epub 2022 Mar 31 doi: 10.1007/s10151-022-02617-w. PMID: 35357610
Beck SH, Jelsig AM, Yassin HM, Lindberg LJ, Wadt KAW, Karstensen JG
Fam Cancer 2022 Oct;21(4):453-462. Epub 2022 Mar 16 doi: 10.1007/s10689-022-00291-3. PMID: 35292903
Lai JH, Park G, Gerson LB
Gastrointest Endosc 2017 Sep;86(3):429-441.e1. Epub 2017 Apr 20 doi: 10.1016/j.gie.2017.04.008. PMID: 28433614
Stanich PP, Pilarski R, Rock J, Frankel WL, El-Dika S, Meyer MM
World J Gastroenterol 2014 Feb 21;20(7):1833-8. doi: 10.3748/wjg.v20.i7.1833. PMID: 24587660Free PMC Article

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