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Leukemic Phase of Lymphoma

MedGen UID:
163423
•Concept ID:
C0852709
•
Neoplastic Process
Synonyms: Leukemic Phase of Non-Hodgkin Lymphoma; Leukemic Phase of Non-Hodgkin's Lymphoma

Definition

A usually terminal event in the clinical course of lymphomas. The term indicates the presence of atypical, clonal (malignant) lymphocytes (lymphoma cells) in the peripheral blood. [from NCI]

Professional guidelines

PubMed

Recent advances in the diagnosis and treatment of natural killer/T-cell lymphomas.
Tse E, Au-Yeung R, Kwong YL
Expert Rev Hematol 2019 Nov;12(11):927-935. Epub 2019 Sep 5 doi: 10.1080/17474086.2019.1660640. PMID: 31487202
Treatment advances and prognosis for patients with adult T-cell leukemia-lymphoma.
Katsuya H, Ishitsuka K
J Clin Exp Hematop 2017 Dec 27;57(3):87-97. Epub 2017 Jun 8 doi: 10.3960/jslrt.17008. PMID: 28592744Free PMC Article
The diagnosis and management of NK/T-cell lymphomas.
Tse E, Kwong YL
J Hematol Oncol 2017 Apr 14;10(1):85. doi: 10.1186/s13045-017-0452-9. PMID: 28410601Free PMC Article

Recent clinical studies

Diagnosis

B-cell lymphosarcoma cell leukemia: dynamics of surface-membrance immunoglobulin. Value for differentiation from chronic lymphocytic leukemia.
Cohen HJ
Ann Intern Med 1978 Mar;88(3):317-22. doi: 10.7326/0003-4819-88-3-317. PMID: 343679
Acute lymphocytic leukemia with atypical cytochemical features.
Shaw MT, Ishmael DR
Am J Clin Pathol 1975 Mar;63(3):415-20. doi: 10.1093/ajcp/63.3.415. PMID: 46699

Therapy

Plasma cell leukemia--a study of 28 cases from India.
Majumdar N, Kumar R, Anand M, Kalita D, Ghara N, Chopra A, Medhi K, Sharma A, Kumar L, Raina V
Hematology 2009 Aug;14(4):198-203. doi: 10.1179/102453309X426191. PMID: 19635182
Acute lymphocytic leukemia with atypical cytochemical features.
Shaw MT, Ishmael DR
Am J Clin Pathol 1975 Mar;63(3):415-20. doi: 10.1093/ajcp/63.3.415. PMID: 46699

Prognosis

Plasma cell leukemia--a study of 28 cases from India.
Majumdar N, Kumar R, Anand M, Kalita D, Ghara N, Chopra A, Medhi K, Sharma A, Kumar L, Raina V
Hematology 2009 Aug;14(4):198-203. doi: 10.1179/102453309X426191. PMID: 19635182

Supplemental Content

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