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Fusiform ascending tubular aorta aneurysm

MedGen UID:
1634425
•Concept ID:
C4703458
•
Disease or Syndrome
HPO: HP:0031643

Definition

A concentric abnormal localized widening (dilatation) of the ascending tubular aorta that involves the full circumference of the vessel wall. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFusiform ascending tubular aorta aneurysm

Conditions with this feature

Aortic aneurysm, familial thoracic 10
MedGen UID:
924785
•Concept ID:
C4284414
•
Disease or Syndrome
Any familial thoracic aortic aneurysm and aortic dissection in which the cause of the disease is a mutation in the LOX gene.
See: Condition Record
Aortic aneurysm, familial thoracic 10

Recent clinical studies

Etiology

Syphilitic aortitis: still a current common cause of aneurysm of the tubular portion of ascending aorta.
Roberts WC, Moore AJ, Roberts CS
Cardiovasc Pathol 2020 May-Jun;46:107175. Epub 2019 Oct 28 doi: 10.1016/j.carpath.2019.107175. PMID: 31951962
Syphilitic aortic aneurysm.
Yuan SM
Z Rheumatol 2018 Oct;77(8):741-748. doi: 10.1007/s00393-018-0519-1. PMID: 30073493
Syphilitic aortitis and its complications in the modern era.
Drago F, Merlo G, Rebora A, Parodi A
G Ital Dermatol Venereol 2018 Oct;153(5):698-706. Epub 2016 Dec 16 doi: 10.23736/S0392-0488.16.05522-X. PMID: 27982548
Endograft repair for pseudoaneurysms and penetrating ulcers of the ascending aorta.
Piffaretti G, Galli M, Lomazzi C, Franchin M, Castelli P, Mariscalco G, Trimarchi S
J Thorac Cardiovasc Surg 2016 Jun;151(6):1606-14. Epub 2016 Jan 13 doi: 10.1016/j.jtcvs.2015.12.055. PMID: 26872446
A modern experience with saccular aortic aneurysms.
Shang EK, Nathan DP, Boonn WW, Lys-Dobradin IA, Fairman RM, Woo EY, Wang GJ, Jackson BM
J Vasc Surg 2013 Jan;57(1):84-8. Epub 2012 Nov 3 doi: 10.1016/j.jvs.2012.07.002. PMID: 23127980

Diagnosis

Syphilitic aortitis: still a current common cause of aneurysm of the tubular portion of ascending aorta.
Roberts WC, Moore AJ, Roberts CS
Cardiovasc Pathol 2020 May-Jun;46:107175. Epub 2019 Oct 28 doi: 10.1016/j.carpath.2019.107175. PMID: 31951962
Syphilitic aortic aneurysm.
Yuan SM
Z Rheumatol 2018 Oct;77(8):741-748. doi: 10.1007/s00393-018-0519-1. PMID: 30073493
Operative Recognition of Syphilis of the Aorta.
Roberts WC, Kondapalli N
Am J Cardiol 2018 Sep 1;122(5):898-904. Epub 2018 Jun 2 doi: 10.1016/j.amjcard.2018.05.030. PMID: 30064859
Syphilitic aortitis and its complications in the modern era.
Drago F, Merlo G, Rebora A, Parodi A
G Ital Dermatol Venereol 2018 Oct;153(5):698-706. Epub 2016 Dec 16 doi: 10.23736/S0392-0488.16.05522-X. PMID: 27982548
Endograft repair for pseudoaneurysms and penetrating ulcers of the ascending aorta.
Piffaretti G, Galli M, Lomazzi C, Franchin M, Castelli P, Mariscalco G, Trimarchi S
J Thorac Cardiovasc Surg 2016 Jun;151(6):1606-14. Epub 2016 Jan 13 doi: 10.1016/j.jtcvs.2015.12.055. PMID: 26872446

Therapy

Syphilitic aortitis: still a current common cause of aneurysm of the tubular portion of ascending aorta.
Roberts WC, Moore AJ, Roberts CS
Cardiovasc Pathol 2020 May-Jun;46:107175. Epub 2019 Oct 28 doi: 10.1016/j.carpath.2019.107175. PMID: 31951962
Open and endovascular repair of the nontraumatic isolated aortic arch aneurysm.
Sood V, Patel HJ, Williams DM, Dasika NL, Yang B, Deeb GM
J Vasc Surg 2014 Jul;60(1):57-63. Epub 2014 Mar 19 doi: 10.1016/j.jvs.2014.01.066. PMID: 24655751
Deployment of proximal thoracic endograft in zone 0 of the ascending aorta: treatment options and early outcomes for aortic arch aneurysms in a high-risk population.
Preventza O, Bakaeen FG, Cervera RD, Coselli JS
Eur J Cardiothorac Surg 2013 Sep;44(3):446-52; discussion 452-3. Epub 2013 Mar 20 doi: 10.1093/ejcts/ezt068. PMID: 23515170
Treatment of fusiform ascending aortic aneurysms: a comparative study with 2 options.
Zhang H, Lu F, Qu D, Han L, Xu J, Ji G, Xu Z
J Thorac Cardiovasc Surg 2011 Mar;141(3):738-43. Epub 2010 Jun 26 doi: 10.1016/j.jtcvs.2010.05.031. PMID: 20584536
Redo operations for recurrent aneurysmal disease of the ascending aorta and transverse aortic arch.
Crawford ES, Crawford JL, Safi HJ, Coselli JS
Ann Thorac Surg 1985 Nov;40(5):439-55. doi: 10.1016/s0003-4975(10)60099-9. PMID: 3904648

Prognosis

Off-Pump Plicating Ascending Aortoplasty With External Wrapping: Magnum in Parvo.
Kocica MJ, Karadzic MM, Cvetkovic DD, Grujic MB, Soskic L
Heart Lung Circ 2019 Dec;28(12):1866-1871. Epub 2018 Nov 3 doi: 10.1016/j.hlc.2018.10.018. PMID: 30424984
Endograft repair for pseudoaneurysms and penetrating ulcers of the ascending aorta.
Piffaretti G, Galli M, Lomazzi C, Franchin M, Castelli P, Mariscalco G, Trimarchi S
J Thorac Cardiovasc Surg 2016 Jun;151(6):1606-14. Epub 2016 Jan 13 doi: 10.1016/j.jtcvs.2015.12.055. PMID: 26872446
A modern experience with saccular aortic aneurysms.
Shang EK, Nathan DP, Boonn WW, Lys-Dobradin IA, Fairman RM, Woo EY, Wang GJ, Jackson BM
J Vasc Surg 2013 Jan;57(1):84-8. Epub 2012 Nov 3 doi: 10.1016/j.jvs.2012.07.002. PMID: 23127980
Treatment of fusiform ascending aortic aneurysms: a comparative study with 2 options.
Zhang H, Lu F, Qu D, Han L, Xu J, Ji G, Xu Z
J Thorac Cardiovasc Surg 2011 Mar;141(3):738-43. Epub 2010 Jun 26 doi: 10.1016/j.jtcvs.2010.05.031. PMID: 20584536
Redo operations for recurrent aneurysmal disease of the ascending aorta and transverse aortic arch.
Crawford ES, Crawford JL, Safi HJ, Coselli JS
Ann Thorac Surg 1985 Nov;40(5):439-55. doi: 10.1016/s0003-4975(10)60099-9. PMID: 3904648

Clinical prediction guides

Endograft repair for pseudoaneurysms and penetrating ulcers of the ascending aorta.
Piffaretti G, Galli M, Lomazzi C, Franchin M, Castelli P, Mariscalco G, Trimarchi S
J Thorac Cardiovasc Surg 2016 Jun;151(6):1606-14. Epub 2016 Jan 13 doi: 10.1016/j.jtcvs.2015.12.055. PMID: 26872446
Open and endovascular repair of the nontraumatic isolated aortic arch aneurysm.
Sood V, Patel HJ, Williams DM, Dasika NL, Yang B, Deeb GM
J Vasc Surg 2014 Jul;60(1):57-63. Epub 2014 Mar 19 doi: 10.1016/j.jvs.2014.01.066. PMID: 24655751
A modern experience with saccular aortic aneurysms.
Shang EK, Nathan DP, Boonn WW, Lys-Dobradin IA, Fairman RM, Woo EY, Wang GJ, Jackson BM
J Vasc Surg 2013 Jan;57(1):84-8. Epub 2012 Nov 3 doi: 10.1016/j.jvs.2012.07.002. PMID: 23127980
Perforation of the ascending aorta with a hematoma extending into the left-side upper extrapleural cavity.
Kadohama T, Akasaka N, Goh K, Sasajima T
Interact Cardiovasc Thorac Surg 2008 Apr;7(2):318-9. Epub 2007 Dec 18 doi: 10.1510/icvts.2007.166066. PMID: 18089615
A new method to treat fusiform aneurysms of the ascending aorta associated with aortic valve disease: an alternative to radical resection.
Robicsek F
Ann Thorac Surg 1982 Jul;34(1):92-4. doi: 10.1016/s0003-4975(10)60860-0. PMID: 7046664

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