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Anterior chamber cells grade 0.5+

MedGen UID:
1634608
•Concept ID:
C4703385
•
Finding
HPO: HP:0025562

Definition

Anterior chamber cells with 1-5 cells in a 1 mm by 1 mm slit beam field, employing adequate light intensity and magnification on a slit lamp. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior chamber cells grade 0.5+

Recent clinical studies

Etiology

Incidence of and Risk Factors for Cataract in Anterior Uveitis.
Papaliodis GN, Rosner BA, Dreger KA, Fitzgerald TD, Artornsombudh P, Kothari S, Gangaputra SS, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE, Bhatt NP, Foster CS, Jabs DA, Pak CM, Ying GS, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Research Group
Am J Ophthalmol 2023 Oct;254:221-232. Epub 2023 Jul 5 doi: 10.1016/j.ajo.2023.06.021. PMID: 37414328Free PMC Article
Intraocular leucocyte subpopulations analysis by multiparametric flow cytometry in human uveitis.
Carreño E, Serrano C, Muñoz N, Romero-Bueno F, Sánchez Pernaute O, Alejandre N
Br J Ophthalmol 2021 Mar;105(3):322-327. Epub 2020 May 18 doi: 10.1136/bjophthalmol-2019-315511. PMID: 32424059
Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children.
Vittitow JL, Williams JI
J Cataract Refract Surg 2020 Aug;46(8):1092-1101. doi: 10.1097/j.jcrs.0000000000000218. PMID: 32352250
Association of Angle Width With Progression of Normal-Tension Glaucoma: A Minimum 7-Year Follow-up Study.
Ha A, Kim YK, Jeoung JW, Kim DM, Park KH
JAMA Ophthalmol 2019 Jan 1;137(1):13-20. doi: 10.1001/jamaophthalmol.2018.4333. PMID: 30326036Free PMC Article
Analysis of ocular inflammation in anterior chamber-involving uveitis using swept-source anterior segment OCT.
Baghdasaryan E, Tepelus TC, Marion KM, Huang J, Huang P, Sadda SR, Lee OL
Int Ophthalmol 2019 Aug;39(8):1793-1801. Epub 2018 Sep 20 doi: 10.1007/s10792-018-1005-0. PMID: 30238391

Diagnosis

Retinal giant cyst treated by the scleral buckling procedure: A case report.
Wang L, Wang Y, Cao X, Jia P, Yuan L, Wang Y, Liu J, An J
Medicine (Baltimore) 2024 Mar 29;103(13):e37620. doi: 10.1097/MD.0000000000037620. PMID: 38552087Free PMC Article
Quantification of Anterior Chamber Cells in Children With Uveitis Using Anterior Segment Optical Coherence Tomography.
Tsui E, Chen JL, Jackson NJ, Leyva O, Rasheed H, Baghdasaryan E, Fung SSM, McCurdy DK, Sadda SR, Holland GN
Am J Ophthalmol 2022 Sep;241:254-261. Epub 2022 May 21 doi: 10.1016/j.ajo.2022.05.012. PMID: 35609675Free PMC Article
Intraocular leucocyte subpopulations analysis by multiparametric flow cytometry in human uveitis.
Carreño E, Serrano C, Muñoz N, Romero-Bueno F, Sánchez Pernaute O, Alejandre N
Br J Ophthalmol 2021 Mar;105(3):322-327. Epub 2020 May 18 doi: 10.1136/bjophthalmol-2019-315511. PMID: 32424059
Association of Angle Width With Progression of Normal-Tension Glaucoma: A Minimum 7-Year Follow-up Study.
Ha A, Kim YK, Jeoung JW, Kim DM, Park KH
JAMA Ophthalmol 2019 Jan 1;137(1):13-20. doi: 10.1001/jamaophthalmol.2018.4333. PMID: 30326036Free PMC Article
Analysis of ocular inflammation in anterior chamber-involving uveitis using swept-source anterior segment OCT.
Baghdasaryan E, Tepelus TC, Marion KM, Huang J, Huang P, Sadda SR, Lee OL
Int Ophthalmol 2019 Aug;39(8):1793-1801. Epub 2018 Sep 20 doi: 10.1007/s10792-018-1005-0. PMID: 30238391

Therapy

Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children.
Vittitow JL, Williams JI
J Cataract Refract Surg 2020 Aug;46(8):1092-1101. doi: 10.1097/j.jcrs.0000000000000218. PMID: 32352250
Efficacy and safety of antifungal additives in Optisol-GS corneal storage medium.
Layer N, Cevallos V, Maxwell AJ, Hoover C, Keenan JD, Jeng BH
JAMA Ophthalmol 2014 Jul;132(7):832-7. doi: 10.1001/jamaophthalmol.2014.397. PMID: 24789459
Loteprednol etabonate ophthalmic gel 0.5% following cataract surgery: integrated analysis of two clinical studies.
Rajpal RK, Fong R, Comstock TL
Adv Ther 2013 Oct;30(10):907-23. Epub 2013 Oct 18 doi: 10.1007/s12325-013-0059-7. PMID: 24136301
Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus.
Leccisotti A
Cornea 2008 May;27(4):417-20. doi: 10.1097/ICO.0b013e318164e4b8. PMID: 18434844
Torsional mode versus conventional ultrasound mode phacoemulsification: randomized comparative clinical study.
Liu Y, Zeng M, Liu X, Luo L, Yuan Z, Xia Y, Zeng Y
J Cataract Refract Surg 2007 Feb;33(2):287-92. doi: 10.1016/j.jcrs.2006.10.044. PMID: 17276271

Prognosis

Incidence of and Risk Factors for Cataract in Anterior Uveitis.
Papaliodis GN, Rosner BA, Dreger KA, Fitzgerald TD, Artornsombudh P, Kothari S, Gangaputra SS, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE, Bhatt NP, Foster CS, Jabs DA, Pak CM, Ying GS, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Research Group
Am J Ophthalmol 2023 Oct;254:221-232. Epub 2023 Jul 5 doi: 10.1016/j.ajo.2023.06.021. PMID: 37414328Free PMC Article
Association of Angle Width With Progression of Normal-Tension Glaucoma: A Minimum 7-Year Follow-up Study.
Ha A, Kim YK, Jeoung JW, Kim DM, Park KH
JAMA Ophthalmol 2019 Jan 1;137(1):13-20. doi: 10.1001/jamaophthalmol.2018.4333. PMID: 30326036Free PMC Article
Characterization of T cells and cytokines in the aqueous humour (AH) in patients with Fuchs' heterochromic cyclitis (FHC) and idiopathic anterior uveitis (IAU).
Muhaya M, Calder V, Towler HM, Shaer B, McLauchlan M, Lightman S
Clin Exp Immunol 1998 Jan;111(1):123-8. doi: 10.1046/j.1365-2249.1998.00428.x. PMID: 9472671Free PMC Article
Membranous outgrowth suggesting lens epithelial cell proliferation in pseudophakic eyes.
Ibaraki N, Ohara K, Miyamoto T
Am J Ophthalmol 1995 Jun;119(6):706-11. doi: 10.1016/s0002-9394(14)72774-6. PMID: 7785683

Clinical prediction guides

Retinal giant cyst treated by the scleral buckling procedure: A case report.
Wang L, Wang Y, Cao X, Jia P, Yuan L, Wang Y, Liu J, An J
Medicine (Baltimore) 2024 Mar 29;103(13):e37620. doi: 10.1097/MD.0000000000037620. PMID: 38552087Free PMC Article
Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children.
Vittitow JL, Williams JI
J Cataract Refract Surg 2020 Aug;46(8):1092-1101. doi: 10.1097/j.jcrs.0000000000000218. PMID: 32352250
Analysis of ocular inflammation in anterior chamber-involving uveitis using swept-source anterior segment OCT.
Baghdasaryan E, Tepelus TC, Marion KM, Huang J, Huang P, Sadda SR, Lee OL
Int Ophthalmol 2019 Aug;39(8):1793-1801. Epub 2018 Sep 20 doi: 10.1007/s10792-018-1005-0. PMID: 30238391
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
Wilson ME, O'Halloran H, VanderVeen D, Roarty J, Plager DA, Markwardt K, Gedif K, Lambert SR
Eye (Lond) 2016 Sep;30(9):1187-94. Epub 2016 Jul 1 doi: 10.1038/eye.2016.132. PMID: 27367745Free PMC Article
Efficacy and safety of antifungal additives in Optisol-GS corneal storage medium.
Layer N, Cevallos V, Maxwell AJ, Hoover C, Keenan JD, Jeng BH
JAMA Ophthalmol 2014 Jul;132(7):832-7. doi: 10.1001/jamaophthalmol.2014.397. PMID: 24789459

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