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Localized Leiomyosarcoma

MedGen UID:
163507
Concept ID:
C0855057
Neoplastic Process
Synonyms: Leiomyosarcoma Nonmetastatic; Non-Metastatic Leiomyosarcoma; Primary leiomyosarcoma
SNOMED CT: Primary leiomyosarcoma (423807009)

Definition

Leiomyosarcoma that is confined to a specific site without evidence of spread to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Leiomyosarcoma

Professional guidelines

PubMed

Engelking M, Rao M
Thorac Surg Clin 2024 May;34(2):189-195. Epub 2024 Feb 24 doi: 10.1016/j.thorsurg.2024.01.009. PMID: 38705667
Kerrison WGJ, Thway K, Jones RL, Huang PH
Crit Rev Oncol Hematol 2023 Apr;184:103955. Epub 2023 Mar 7 doi: 10.1016/j.critrevonc.2023.103955. PMID: 36893945
Sassa N
Int J Urol 2020 Dec;27(12):1058-1070. Epub 2020 Sep 10 doi: 10.1111/iju.14361. PMID: 32914475

Recent clinical studies

Etiology

Pautier P, Italiano A, Piperno-Neumann S, Chevreau C, Penel N, Firmin N, Boudou-Rouquette P, Bertucci F, Lebrun-Ly V, Ray-Coquard I, Kalbacher E, Bompas E, Collard O, Isambert N, Guillemet C, Rios M, Le Cesne A, Balleyguier C, Archambaud B, Duffaud F; French Sarcoma Group
N Engl J Med 2024 Sep 5;391(9):789-799. doi: 10.1056/NEJMoa2403394. PMID: 39231341
Walocko F, Christensen RE, Worley B, Alam M
Dermatol Clin 2023 Jan;41(1):133-140. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.011. PMID: 36410974
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Pautier P, Italiano A, Piperno-Neumann S, Chevreau C, Penel N, Firmin N, Boudou-Rouquette P, Bertucci F, Balleyguier C, Lebrun-Ly V, Ray-Coquard I, Kalbacher E, Bardet A, Bompas E, Collard O, Isambert N, Guillemet C, Rios M, Archambaud B, Duffaud F; French Sarcoma Group
Lancet Oncol 2022 Aug;23(8):1044-1054. Epub 2022 Jul 11 doi: 10.1016/S1470-2045(22)00380-1. PMID: 35835135
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869

Diagnosis

Kerrison WGJ, Thway K, Jones RL, Huang PH
Crit Rev Oncol Hematol 2023 Apr;184:103955. Epub 2023 Mar 7 doi: 10.1016/j.critrevonc.2023.103955. PMID: 36893945
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Ding Y, Quan C
J Coll Physicians Surg Pak 2021 Jun;31(6):725-727. doi: 10.29271/jcpsp.2021.06.725. PMID: 34102790
Llombart B, Serra-Guillén C, Requena C, Alsina M, Morgado-Carrasco D, Machado I, Sanmartín O
Actas Dermosifiliogr (Engl Ed) 2019 Jan-Feb;110(1):4-11. Epub 2018 Nov 5 doi: 10.1016/j.ad.2018.06.012. PMID: 30409380
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869

Therapy

Pautier P, Italiano A, Piperno-Neumann S, Chevreau C, Penel N, Firmin N, Boudou-Rouquette P, Bertucci F, Lebrun-Ly V, Ray-Coquard I, Kalbacher E, Bompas E, Collard O, Isambert N, Guillemet C, Rios M, Le Cesne A, Balleyguier C, Archambaud B, Duffaud F; French Sarcoma Group
N Engl J Med 2024 Sep 5;391(9):789-799. doi: 10.1056/NEJMoa2403394. PMID: 39231341
Callegaro D, Raut CP, Ajayi T, Strauss D, Bonvalot S, Ng D, Stoeckle E, Fairweather M, Rutkowski P, van Houdt WJ, Gelderblom H, Sangalli C, Hayes A, Honoré C, Gladdy RA, Fau M, Haas R, Tzanis D, Miah AB, Chung P, Baldini EH, Marreaud S, Litiere S, Swallow CJ, Gronchi A
Ann Surg 2023 Jul 1;278(1):127-134. Epub 2022 Jul 14 doi: 10.1097/SLA.0000000000005492. PMID: 35833413
Pautier P, Italiano A, Piperno-Neumann S, Chevreau C, Penel N, Firmin N, Boudou-Rouquette P, Bertucci F, Balleyguier C, Lebrun-Ly V, Ray-Coquard I, Kalbacher E, Bardet A, Bompas E, Collard O, Isambert N, Guillemet C, Rios M, Archambaud B, Duffaud F; French Sarcoma Group
Lancet Oncol 2022 Aug;23(8):1044-1054. Epub 2022 Jul 11 doi: 10.1016/S1470-2045(22)00380-1. PMID: 35835135
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869

Prognosis

Chang HY, Dermawan J, Sharma A, Dickson B, Turashvili G, Torrence D, Nucci M, Chiang S, Oliva E, Kirchner M, Stenzinger A, Mechtersheimer G, Antonescu C
Mod Pathol 2024 Feb;37(2):100402. Epub 2023 Dec 21 doi: 10.1016/j.modpat.2023.100402. PMID: 38141829Free PMC Article
Kerrison WGJ, Thway K, Jones RL, Huang PH
Crit Rev Oncol Hematol 2023 Apr;184:103955. Epub 2023 Mar 7 doi: 10.1016/j.critrevonc.2023.103955. PMID: 36893945
Pautier P, Italiano A, Piperno-Neumann S, Chevreau C, Penel N, Firmin N, Boudou-Rouquette P, Bertucci F, Balleyguier C, Lebrun-Ly V, Ray-Coquard I, Kalbacher E, Bardet A, Bompas E, Collard O, Isambert N, Guillemet C, Rios M, Archambaud B, Duffaud F; French Sarcoma Group
Lancet Oncol 2022 Aug;23(8):1044-1054. Epub 2022 Jul 11 doi: 10.1016/S1470-2045(22)00380-1. PMID: 35835135
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869
Kaddu S, Beham A, Cerroni L, Humer-Fuchs U, Salmhofer W, Kerl H, Soyer HP
Am J Surg Pathol 1997 Sep;21(9):979-87. doi: 10.1097/00000478-199709000-00001. PMID: 9298873

Clinical prediction guides

Callegaro D, Raut CP, Ajayi T, Strauss D, Bonvalot S, Ng D, Stoeckle E, Fairweather M, Rutkowski P, van Houdt WJ, Gelderblom H, Sangalli C, Hayes A, Honoré C, Gladdy RA, Fau M, Haas R, Tzanis D, Miah AB, Chung P, Baldini EH, Marreaud S, Litiere S, Swallow CJ, Gronchi A
Ann Surg 2023 Jul 1;278(1):127-134. Epub 2022 Jul 14 doi: 10.1097/SLA.0000000000005492. PMID: 35833413
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Gronchi A, Palmerini E, Quagliuolo V, Martin Broto J, Lopez Pousa A, Grignani G, Brunello A, Blay JY, Tendero O, Diaz Beveridge R, Ferraresi V, Lugowska I, Merlo DF, Fontana V, Marchesi E, Braglia L, Donati DM, Palassini E, Bianchi G, Marrari A, Morosi C, Stacchiotti S, Bagué S, Coindre JM, Dei Tos AP, Picci P, Bruzzi P, Casali PG
J Clin Oncol 2020 Jul 1;38(19):2178-2186. Epub 2020 May 18 doi: 10.1200/JCO.19.03289. PMID: 32421444
Tap WD, Wagner AJ, Schöffski P, Martin-Broto J, Krarup-Hansen A, Ganjoo KN, Yen CC, Abdul Razak AR, Spira A, Kawai A, Le Cesne A, Van Tine BA, Naito Y, Park SH, Fedenko A, Pápai Z, Soldatenkova V, Shahir A, Mo G, Wright J, Jones RL; ANNOUNCE Investigators
JAMA 2020 Apr 7;323(13):1266-1276. doi: 10.1001/jama.2020.1707. PMID: 32259228Free PMC Article
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869

Recent systematic reviews

Zamarud A, Marianayagam NJ, Sekar V, Testa S, Park DJ, Yener U, McCleary TL, Yoo KH, Emrich S, Tayag A, Ustrzynski L, Pollom E, Soltys S, Wang L, Charville G, Ganjoo K, Chang SD, Meola A
J Neurosurg Spine 2024 Apr 1;40(4):485-497. Epub 2023 Dec 29 doi: 10.3171/2023.10.SPINE23666. PMID: 38157539
Ijaz I, Shahzad MN, Hosseinifard H, Liu S, Sefidan MO, Kahloon LE, Imani S, Hua Z, Zhang YQ
Cancer Med 2023 Jul;12(13):13894-13911. Epub 2023 Apr 20 doi: 10.1002/cam4.5930. PMID: 37081717Free PMC Article
Kannan S, Chong HH, Chew B, Ferguson JD, Galloway E, McCulloch T, Rankin KS, Ashford RU
World J Surg Oncol 2022 Apr 18;20(1):124. doi: 10.1186/s12957-022-02584-4. PMID: 35436892Free PMC Article
Neuwirth MG, Song Y, Sinnamon AJ, Fraker DL, Zager JS, Karakousis GC
Ann Surg Oncol 2017 Dec;24(13):3803-3810. Epub 2017 Oct 11 doi: 10.1245/s10434-017-6109-7. PMID: 29022281
Gupta AA, Yao X, Verma S, Mackay H, Hopkins L; Sarcoma Disease Site Group and the Gynecology Cancer Disease Site Group
Clin Oncol (R Coll Radiol) 2013 Jun;25(6):346-55. Epub 2013 Jan 5 doi: 10.1016/j.clon.2012.11.008. PMID: 23295078

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