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Localized Leiomyosarcoma

MedGen UID:
163507
Concept ID:
C0855057
Neoplastic Process
Synonyms: Leiomyosarcoma Nonmetastatic; Non-Metastatic Leiomyosarcoma; Primary leiomyosarcoma
SNOMED CT: Primary leiomyosarcoma (423807009)

Definition

Leiomyosarcoma that is confined to a specific site without evidence of spread to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Leiomyosarcoma

Professional guidelines

PubMed

Bonvalot S, Roland C, Raut C, Le Péchoux C, Tzanis D, Frezza AM, Gronchi A
Eur J Surg Oncol 2023 Jun;49(6):1061-1067. Epub 2022 May 16 doi: 10.1016/j.ejso.2022.05.010. PMID: 35599138
Sassa N
Int J Urol 2020 Dec;27(12):1058-1070. Epub 2020 Sep 10 doi: 10.1111/iju.14361. PMID: 32914475
Sampath S, Gaffney DK
Best Pract Res Clin Obstet Gynaecol 2011 Dec;25(6):761-72. Epub 2011 Jul 23 doi: 10.1016/j.bpobgyn.2011.06.004. PMID: 21783424

Recent clinical studies

Etiology

Ng D, Bertrand A, Sanfilippo R, Callegaro D
Expert Rev Anticancer Ther 2023 Jul-Dec;23(11):1169-1178. Epub 2023 Oct 27 doi: 10.1080/14737140.2023.2266137. PMID: 37791587
Kerrison WGJ, Thway K, Jones RL, Huang PH
Crit Rev Oncol Hematol 2023 Apr;184:103955. Epub 2023 Mar 7 doi: 10.1016/j.critrevonc.2023.103955. PMID: 36893945
Walocko F, Christensen RE, Worley B, Alam M
Dermatol Clin 2023 Jan;41(1):133-140. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.011. PMID: 36410974
Desar IME, Ottevanger PB, Benson C, van der Graaf WTA
Crit Rev Oncol Hematol 2018 Feb;122:10-20. Epub 2017 Dec 14 doi: 10.1016/j.critrevonc.2017.12.009. PMID: 29458779
Porter CJ, Januszkiewicz JS
Plast Reconstr Surg 2002 Mar;109(3):964-7. doi: 10.1097/00006534-200203000-00024. PMID: 11884817

Diagnosis

Helbig D, Dippel E, Erdmann M, Frisman A, Kage P, Leiter U, Mentzel T, Seidel C, Weishaupt C, Ziemer M, Ugurel S
J Dtsch Dermatol Ges 2023 May;21(5):555-563. Epub 2023 Mar 31 doi: 10.1111/ddg.14989. PMID: 36999582
Kerrison WGJ, Thway K, Jones RL, Huang PH
Crit Rev Oncol Hematol 2023 Apr;184:103955. Epub 2023 Mar 7 doi: 10.1016/j.critrevonc.2023.103955. PMID: 36893945
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869
Blaise G, Nikkels AF, Quatresooz P, Hermanns-Lê T, Piérard GE
Pediatr Dermatol 2009 Jul-Aug;26(4):477-9. doi: 10.1111/j.1525-1470.2009.00961.x. PMID: 19689533
De Waele B, Van Belle S, Claes H, Goovaerts G, Delvaux G, Willems G
Acta Chir Belg 1987 Jul-Aug;87(4):229-34. PMID: 3661002

Therapy

Bonvalot S, Roland C, Raut C, Le Péchoux C, Tzanis D, Frezza AM, Gronchi A
Eur J Surg Oncol 2023 Jun;49(6):1061-1067. Epub 2022 May 16 doi: 10.1016/j.ejso.2022.05.010. PMID: 35599138
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299
Shah SH, Jagannathan JP, Krajewski K, O'Regan KN, George S, Ramaiya NH
AJR Am J Roentgenol 2012 Jul;199(1):213-23. doi: 10.2214/AJR.11.7287. PMID: 22733915
Blanke CD, Eisenberg BL, Heinrich MC
Curr Treat Options Oncol 2001 Dec;2(6):485-91. doi: 10.1007/s11864-001-0070-0. PMID: 12057094

Prognosis

Pautier P, Italiano A, Piperno-Neumann S, Chevreau C, Penel N, Firmin N, Boudou-Rouquette P, Bertucci F, Balleyguier C, Lebrun-Ly V, Ray-Coquard I, Kalbacher E, Bardet A, Bompas E, Collard O, Isambert N, Guillemet C, Rios M, Archambaud B, Duffaud F; French Sarcoma Group
Lancet Oncol 2022 Aug;23(8):1044-1054. Epub 2022 Jul 11 doi: 10.1016/S1470-2045(22)00380-1. PMID: 35835135
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869
Angelini A, Barastegui D, Gambarotti M, Ruggieri P
Handchir Mikrochir Plast Chir 2015 Apr;47(2):139-41. Epub 2015 Apr 21 doi: 10.1055/s-0034-1395605. PMID: 25897583
Porter CJ, Januszkiewicz JS
Plast Reconstr Surg 2002 Mar;109(3):964-7. doi: 10.1097/00006534-200203000-00024. PMID: 11884817
De Waele B, Van Belle S, Claes H, Goovaerts G, Delvaux G, Willems G
Acta Chir Belg 1987 Jul-Aug;87(4):229-34. PMID: 3661002

Clinical prediction guides

Dingley B, Fiore M, Gronchi A
Expert Rev Anticancer Ther 2019 Jul;19(7):613-631. Epub 2019 Jun 8 doi: 10.1080/14737140.2019.1625774. PMID: 31159625
Juhasz-Böss I, Gabriel L, Bohle RM, Horn LC, Solomayer EF, Breitbach GP
Oncol Res Treat 2018;41(11):680-686. Epub 2018 Oct 16 doi: 10.1159/000494299. PMID: 30321869
Hyman DM, Grisham RN, Hensley ML
Curr Opin Oncol 2014 Jul;26(4):422-7. doi: 10.1097/CCO.0000000000000094. PMID: 24840518
Porter CJ, Januszkiewicz JS
Plast Reconstr Surg 2002 Mar;109(3):964-7. doi: 10.1097/00006534-200203000-00024. PMID: 11884817
Ikari Y, Tokuhashi I, Haramoto I, Morita M, Chiba T, Shimoda N, Mizoguchi M, Seki K, Tadokoro M, Ohya K
J Dermatol 1992 Feb;19(2):99-104. doi: 10.1111/j.1346-8138.1992.tb03188.x. PMID: 1377726

Recent systematic reviews

Annicchiarico A, Montali F, Baldinu M, Casali L, Virgilio E, Costi R
J Surg Oncol 2024 Feb;129(2):365-380. Epub 2023 Oct 10 doi: 10.1002/jso.27481. PMID: 37814590
Kannan S, Chong HH, Chew B, Ferguson JD, Galloway E, McCulloch T, Rankin KS, Ashford RU
World J Surg Oncol 2022 Apr 18;20(1):124. doi: 10.1186/s12957-022-02584-4. PMID: 35436892Free PMC Article
Saikia J, Rastogi S, Barwad A, Dhamija E, Pandey R, Bhoriwal S, Deo S, Kumar S
Asian Cardiovasc Thorac Ann 2022 Mar;30(3):349-363. Epub 2021 Oct 21 doi: 10.1177/02184923211049911. PMID: 34672808
Murphy-Chutorian B, Routt E, Vinelli G, Ciocon D
Dermatol Surg 2019 Dec;45(12):1437-1441. doi: 10.1097/DSS.0000000000001992. PMID: 31397774
Surov A, Gottschling S, Wienke A, Meyer HJ, Spielmann RP, Dralle H
Anticancer Res 2015 Oct;35(10):5185-91. PMID: 26408676

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