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Malignant epithelioid mesothelioma

MedGen UID:
163578
Concept ID:
C0862312
Neoplastic Process
Synonyms: Epithelial Mesothelioma; epithelial mesothelioma; Epithelioid Mesothelioma; Epithelioid mesothelioma; epithelioid mesothelioma; Epithelioid mesothelioma, malignant; epithelioid mesothelioma, malignant; epithelioid mesothelioma, malignant (morphologic abnormality); Malignant Epithelial Mesothelioma; malignant epithelial mesothelioma; malignant epithelioid mesothelioma
SNOMED CT: Epithelioid mesothelioma, malignant (65278006); Epithelioid mesothelioma (65278006); Malignant epithelioid mesothelioma (65278006)
 
Monarch Initiative: MONDO:0005599

Definition

A malignant neoplasm arising from mesothelial cells. It is characterized by the presence of cells with epithelioid morphology. The epithelioid cells usually have eosinophilic cytoplasm, bland nuclei, and form tubulopapillary, microglandular, or sheet-like patterns. [from NCI]

Professional guidelines

PubMed

Le Stang N, Burke L, Blaizot G, Gibbs AR, Lebailly P, Clin B, Girard N, Galateau-Sallé F; MESOPATH and EURACAN networks
Arch Pathol Lab Med 2020 Apr;144(4):446-456. Epub 2019 Aug 7 doi: 10.5858/arpa.2018-0457-OA. PMID: 31389715
Giger-Pabst U, Demtröder C, Falkenstein TA, Ouaissi M, Götze TO, Rezniczek GA, Tempfer CB
BMC Cancer 2018 Apr 18;18(1):442. doi: 10.1186/s12885-018-4363-0. PMID: 29669524Free PMC Article
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896

Recent clinical studies

Etiology

Ramos Arias G, Sindayigaya R, Ouaissi M, Buggisch JR, Schmeding M, Giger-Pabst U, Zieren J
Ann Surg Oncol 2023 Apr;30(4):2497-2505. Epub 2022 Nov 18 doi: 10.1245/s10434-022-12698-4. PMID: 36400887
Forest F, Laville D, Habougit C, Corbasson M, Bayle-Bleuez S, Tissot C, Fournel P, Tiffet O, Péoc'h M
Pathology 2021 Oct;53(6):728-734. Epub 2021 May 6 doi: 10.1016/j.pathol.2021.01.010. PMID: 33965253
Giger-Pabst U, Demtröder C, Falkenstein TA, Ouaissi M, Götze TO, Rezniczek GA, Tempfer CB
BMC Cancer 2018 Apr 18;18(1):442. doi: 10.1186/s12885-018-4363-0. PMID: 29669524Free PMC Article

Diagnosis

Forest F, Laville D, Habougit C, Corbasson M, Bayle-Bleuez S, Tissot C, Fournel P, Tiffet O, Péoc'h M
Pathology 2021 Oct;53(6):728-734. Epub 2021 May 6 doi: 10.1016/j.pathol.2021.01.010. PMID: 33965253
Collins K, Nagarajan P, Aung PP
J Cutan Pathol 2021 Jul;48(7):902-907. Epub 2020 Dec 14 doi: 10.1111/cup.13927. PMID: 33258154
Xing D, Banet N, Sharma R, Vang R, Ronnett BM, Illei PB
Hum Pathol 2018 Feb;72:160-166. Epub 2017 Dec 11 doi: 10.1016/j.humpath.2017.10.036. PMID: 29241740
Paliogiannis P, Putzu C, Ginesu GC, Cossu ML, Feo CF, Attene F, Scognamillo F, Nonnis R, Cossu A, Palmieri G, Pirina P, Fois A
Clin Respir J 2018 Mar;12(3):848-856. Epub 2017 Jan 6 doi: 10.1111/crj.12599. PMID: 28026144
Mino JS, Monteiro R, Pigalarga R, Varghese S, Guisto L, Rezac C
BMJ Case Rep 2014 Feb 5;2014 doi: 10.1136/bcr-2013-200212. PMID: 24501333Free PMC Article

Therapy

Giger-Pabst U, Demtröder C, Falkenstein TA, Ouaissi M, Götze TO, Rezniczek GA, Tempfer CB
BMC Cancer 2018 Apr 18;18(1):442. doi: 10.1186/s12885-018-4363-0. PMID: 29669524Free PMC Article
Paliogiannis P, Putzu C, Ginesu GC, Cossu ML, Feo CF, Attene F, Scognamillo F, Nonnis R, Cossu A, Palmieri G, Pirina P, Fois A
Clin Respir J 2018 Mar;12(3):848-856. Epub 2017 Jan 6 doi: 10.1111/crj.12599. PMID: 28026144
Tsai LY, Yang YL, Lu MY, Lin DT, Huang HY, Lin KH
Pediatr Hematol Oncol 2010 Mar;27(2):132-7. doi: 10.3109/08880010903447359. PMID: 20201694
Wheeler YY, Burroughs F, Li QK
Diagn Cytopathol 2009 Oct;37(10):748-54. doi: 10.1002/dc.21084. PMID: 19373910

Prognosis

Forest F, Laville D, Habougit C, Corbasson M, Bayle-Bleuez S, Tissot C, Fournel P, Tiffet O, Péoc'h M
Pathology 2021 Oct;53(6):728-734. Epub 2021 May 6 doi: 10.1016/j.pathol.2021.01.010. PMID: 33965253
Collins K, Nagarajan P, Aung PP
J Cutan Pathol 2021 Jul;48(7):902-907. Epub 2020 Dec 14 doi: 10.1111/cup.13927. PMID: 33258154
Paliogiannis P, Putzu C, Ginesu GC, Cossu ML, Feo CF, Attene F, Scognamillo F, Nonnis R, Cossu A, Palmieri G, Pirina P, Fois A
Clin Respir J 2018 Mar;12(3):848-856. Epub 2017 Jan 6 doi: 10.1111/crj.12599. PMID: 28026144
Yildiz H, Andreea SI, Hoton D, Yombi JC
BMJ Case Rep 2016 Dec 19;2016 doi: 10.1136/bcr-2016-217958. PMID: 27993826Free PMC Article
Kothmaier H, Quehenberger F, Halbwedl I, Morbini P, Demirag F, Zeren H, Comin CE, Murer B, Cagle PT, Attanoos R, Gibbs AR, Galateau-Salle F, Popper HH
Thorax 2008 Apr;63(4):345-51. Epub 2007 Dec 17 doi: 10.1136/thx.2007.085241. PMID: 18086752

Clinical prediction guides

Ramos Arias G, Sindayigaya R, Ouaissi M, Buggisch JR, Schmeding M, Giger-Pabst U, Zieren J
Ann Surg Oncol 2023 Apr;30(4):2497-2505. Epub 2022 Nov 18 doi: 10.1245/s10434-022-12698-4. PMID: 36400887
Giger-Pabst U, Demtröder C, Falkenstein TA, Ouaissi M, Götze TO, Rezniczek GA, Tempfer CB
BMC Cancer 2018 Apr 18;18(1):442. doi: 10.1186/s12885-018-4363-0. PMID: 29669524Free PMC Article
Wick MR, Mills SE, Swanson PE
Am J Clin Pathol 1990 Jul;94(1):18-26. doi: 10.1093/ajcp/94.1.18. PMID: 1694390

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