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Lacrimal pump failure

MedGen UID:
1636062
Concept ID:
C4703508
Disease or Syndrome
HPO: HP:0031734

Definition

A form of watery eye associated with abnormal lid tone and/or lid position. The former is due to lid laxity (common involutional change in the elderly) or a weak orbicularis muscle (e.g. due to VII cranial nerve palsy). The latter is typically associated with ectropion causing punctal eversion. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLacrimal pump failure

Professional guidelines

Recent clinical studies

Etiology

Hodgson K, Hussain A
J Craniofac Surg 2024 Mar-Apr 01;35(2):501-504. Epub 2023 Oct 10 doi: 10.1097/SCS.0000000000009783. PMID: 37815386
Al-Faky YH
Br J Ophthalmol 2013 Oct;97(10):1325-9. Epub 2013 Aug 12 doi: 10.1136/bjophthalmol-2013-303662. PMID: 23940269
Madge SN, Malhotra R, Desousa J, McNab A, O'Donnell B, Dolman P, Selva D
Am J Ophthalmol 2010 Jan;149(1):155-9. Epub 2009 Nov 6 doi: 10.1016/j.ajo.2009.08.012. PMID: 19896634
Guercio B, Keyhani K, Weinberg DA
Orbit 2007 Mar;26(1):15-8. doi: 10.1080/01676830600975164. PMID: 17510865
Vick VL, Holds JB, Hartstein ME, Massry GG
Ophthalmic Plast Reconstr Surg 2004 Jan;20(1):37-9. doi: 10.1097/01.IOP.0000103005.81708.FD. PMID: 14752308

Diagnosis

Al-Faky YH
Br J Ophthalmol 2013 Oct;97(10):1325-9. Epub 2013 Aug 12 doi: 10.1136/bjophthalmol-2013-303662. PMID: 23940269
Madge SN, Malhotra R, Desousa J, McNab A, O'Donnell B, Dolman P, Selva D
Am J Ophthalmol 2010 Jan;149(1):155-9. Epub 2009 Nov 6 doi: 10.1016/j.ajo.2009.08.012. PMID: 19896634
Dutton JJ
Arch Ophthalmol 1989 Jul;107(7):1010-2. doi: 10.1001/archopht.1989.01070020072032. PMID: 2665695

Prognosis

Hodgson K, Hussain A
J Craniofac Surg 2024 Mar-Apr 01;35(2):501-504. Epub 2023 Oct 10 doi: 10.1097/SCS.0000000000009783. PMID: 37815386

Clinical prediction guides

Hodgson K, Hussain A
J Craniofac Surg 2024 Mar-Apr 01;35(2):501-504. Epub 2023 Oct 10 doi: 10.1097/SCS.0000000000009783. PMID: 37815386
Al-Faky YH
Br J Ophthalmol 2013 Oct;97(10):1325-9. Epub 2013 Aug 12 doi: 10.1136/bjophthalmol-2013-303662. PMID: 23940269

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