U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Epilepsy, hot water, 1(HWE1)

MedGen UID:
1636069
•Concept ID:
C4551550
•
Disease or Syndrome
Synonym: HWE1
 
Monarch Initiative: MONDO:0024508
OMIM®: 613339

Clinical features

From HPO
Febrile seizure (within the age range of 3 months to 6 years)
MedGen UID:
3232
•Concept ID:
C0009952
•
Disease or Syndrome
A febrile seizure is any type of seizure (most often a generalized tonic-clonic seizure) occurring with fever (at least 38 degrees Celsius) but in the absence of central nervous system infection, severe metabolic disturbance or other alternative precipitant in children between the ages of 3 months and 6 years.
See: Feature record | Search on this feature
Drowsiness
MedGen UID:
4390
•Concept ID:
C0013144
•
Finding
Abnormal feeling of sleepiness or difficulty staying awake.
See: Feature record | Search on this feature
Hypotonia
MedGen UID:
10133
•Concept ID:
C0026827
•
Finding
Hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle). Even when relaxed, muscles have a continuous and passive partial contraction which provides some resistance to passive stretching. Hypotonia thus manifests as diminished resistance to passive stretching. Hypotonia is not the same as muscle weakness, although the two conditions can co-exist.
See: Feature record | Search on this feature
Generalized hypotonia
MedGen UID:
346841
•Concept ID:
C1858120
•
Finding
Generalized muscular hypotonia (abnormally low muscle tone).
See: Feature record | Search on this feature
Show allHide all

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Reflex Epilepsy with Hot Water: Clinical and EEG Findings, Treatment, and Prognosis in Childhood.
Hanci F, Türay S, Balci P, Kabakuş N
Neuropediatrics 2020 Oct;51(5):336-340. Epub 2020 Apr 15 doi: 10.1055/s-0040-1709455. PMID: 32294767
Hot water epilepsy clinical profile and treatment--a prospective study.
Meghana A, Sinha S, Sathyaprabha TN, Subbakrishna DK, Satishchandra P
Epilepsy Res 2012 Dec;102(3):160-6. Epub 2012 Jun 22 doi: 10.1016/j.eplepsyres.2012.05.011. PMID: 22727658
Hot water epilepsy: seizure type, water temperature, EEG findings and treatment.
Zeki G, Ilker IH, Hidir UU, Zeki O
Neurologist 2010 Mar;16(2):109-12. doi: 10.1097/NRL.0b013e3181bd603c. PMID: 20220445

Recent clinical studies

Etiology

Hot water epilepsy with alone and spontaneous seizures in childhood.
Yimenicioğlu S, Ekici A
Epilepsy Res 2024 Sep;205:107418. Epub 2024 Jul 14 doi: 10.1016/j.eplepsyres.2024.107418. PMID: 39003967
Long-term clinical course and prognosis of hot water epilepsy: 15-Year follow-up.
Balgetir F, Gönen M, Müngen E, Berilgen A, Müngen B
Epilepsy Behav 2022 Apr;129:108607. Epub 2022 Feb 15 doi: 10.1016/j.yebeh.2022.108607. PMID: 35180572
Clinical, Demographic, and Electroencephalographic Profile of Hot-Water Epilepsy in Children.
Bharathi NK, Shivappa SK, Gowda VK, Shivalingaiah S, Benakappa A
Indian J Pediatr 2021 Sep;88(9):885-891. Epub 2021 Jan 8 doi: 10.1007/s12098-020-03570-y. PMID: 33417183
Reflex Epilepsy with Hot Water: Clinical and EEG Findings, Treatment, and Prognosis in Childhood.
Hanci F, Türay S, Balci P, Kabakuş N
Neuropediatrics 2020 Oct;51(5):336-340. Epub 2020 Apr 15 doi: 10.1055/s-0040-1709455. PMID: 32294767
Hot water epilepsy clinical profile and treatment--a prospective study.
Meghana A, Sinha S, Sathyaprabha TN, Subbakrishna DK, Satishchandra P
Epilepsy Res 2012 Dec;102(3):160-6. Epub 2012 Jun 22 doi: 10.1016/j.eplepsyres.2012.05.011. PMID: 22727658

Diagnosis

Hot water epilepsy with alone and spontaneous seizures in childhood.
Yimenicioğlu S, Ekici A
Epilepsy Res 2024 Sep;205:107418. Epub 2024 Jul 14 doi: 10.1016/j.eplepsyres.2024.107418. PMID: 39003967
Long-term clinical course and prognosis of hot water epilepsy: 15-Year follow-up.
Balgetir F, Gönen M, Müngen E, Berilgen A, Müngen B
Epilepsy Behav 2022 Apr;129:108607. Epub 2022 Feb 15 doi: 10.1016/j.yebeh.2022.108607. PMID: 35180572
Clinical, Demographic, and Electroencephalographic Profile of Hot-Water Epilepsy in Children.
Bharathi NK, Shivappa SK, Gowda VK, Shivalingaiah S, Benakappa A
Indian J Pediatr 2021 Sep;88(9):885-891. Epub 2021 Jan 8 doi: 10.1007/s12098-020-03570-y. PMID: 33417183
Reflex Epilepsy with Hot Water: Clinical and EEG Findings, Treatment, and Prognosis in Childhood.
Hanci F, Türay S, Balci P, Kabakuş N
Neuropediatrics 2020 Oct;51(5):336-340. Epub 2020 Apr 15 doi: 10.1055/s-0040-1709455. PMID: 32294767
Reflex seizures and reflex epilepsy.
Xue LY, Ritaccio AL
Am J Electroneurodiagnostic Technol 2006 Mar;46(1):39-48. PMID: 16605171

Therapy

Hot water epilepsy with alone and spontaneous seizures in childhood.
Yimenicioğlu S, Ekici A
Epilepsy Res 2024 Sep;205:107418. Epub 2024 Jul 14 doi: 10.1016/j.eplepsyres.2024.107418. PMID: 39003967
Long-term clinical course and prognosis of hot water epilepsy: 15-Year follow-up.
Balgetir F, Gönen M, Müngen E, Berilgen A, Müngen B
Epilepsy Behav 2022 Apr;129:108607. Epub 2022 Feb 15 doi: 10.1016/j.yebeh.2022.108607. PMID: 35180572
Reflex Epilepsy with Hot Water: Clinical and EEG Findings, Treatment, and Prognosis in Childhood.
Hanci F, Türay S, Balci P, Kabakuş N
Neuropediatrics 2020 Oct;51(5):336-340. Epub 2020 Apr 15 doi: 10.1055/s-0040-1709455. PMID: 32294767
Hot water epilepsy clinical profile and treatment--a prospective study.
Meghana A, Sinha S, Sathyaprabha TN, Subbakrishna DK, Satishchandra P
Epilepsy Res 2012 Dec;102(3):160-6. Epub 2012 Jun 22 doi: 10.1016/j.eplepsyres.2012.05.011. PMID: 22727658
Reflex seizures and reflex epilepsy.
Xue LY, Ritaccio AL
Am J Electroneurodiagnostic Technol 2006 Mar;46(1):39-48. PMID: 16605171

Prognosis

Long-term clinical course and prognosis of hot water epilepsy: 15-Year follow-up.
Balgetir F, Gönen M, Müngen E, Berilgen A, Müngen B
Epilepsy Behav 2022 Apr;129:108607. Epub 2022 Feb 15 doi: 10.1016/j.yebeh.2022.108607. PMID: 35180572
Reflex Epilepsy with Hot Water: Clinical and EEG Findings, Treatment, and Prognosis in Childhood.
Hanci F, Türay S, Balci P, Kabakuş N
Neuropediatrics 2020 Oct;51(5):336-340. Epub 2020 Apr 15 doi: 10.1055/s-0040-1709455. PMID: 32294767
Intermittent clobazam prophylaxis in hot water epilepsy is safe and effective: a prospective study.
Satishchandra P, Dilipkumar S, Subbakrishna DK, Sinha S
Epilepsy Res 2014 Sep;108(7):1238-42. Epub 2014 May 27 doi: 10.1016/j.eplepsyres.2014.04.016. PMID: 24929679
Hot water epilepsy: seizure type, water temperature, EEG findings and treatment.
Zeki G, Ilker IH, Hidir UU, Zeki O
Neurologist 2010 Mar;16(2):109-12. doi: 10.1097/NRL.0b013e3181bd603c. PMID: 20220445
Hot water epilepsy: clinical and electrophysiologic findings based on 21 cases.
Bebek N, Gürses C, Gokyigit A, Baykan B, Ozkara C, Dervent A
Epilepsia 2001 Sep;42(9):1180-4. doi: 10.1046/j.1528-1157.2001.31000.x. PMID: 11580768

Clinical prediction guides

Clinical, Demographic, and Electroencephalographic Profile of Hot-Water Epilepsy in Children.
Bharathi NK, Shivappa SK, Gowda VK, Shivalingaiah S, Benakappa A
Indian J Pediatr 2021 Sep;88(9):885-891. Epub 2021 Jan 8 doi: 10.1007/s12098-020-03570-y. PMID: 33417183
A genetic locus for sensory epilepsy precipitated by contact with hot water maps to chromosome 9p24.3-p23.
Karan KR, Satishchandra P, Sinha S, Anand A
J Genet 2018 Jun;97(2):391-398. PMID: 29932058
Hot water epilepsy clinical profile and treatment--a prospective study.
Meghana A, Sinha S, Sathyaprabha TN, Subbakrishna DK, Satishchandra P
Epilepsy Res 2012 Dec;102(3):160-6. Epub 2012 Jun 22 doi: 10.1016/j.eplepsyres.2012.05.011. PMID: 22727658
Hot water epilepsy: clinical and electroencephalographic features of 25 cases.
Yalçin AD, Toydemir HE, Forta H
Epilepsy Behav 2006 Aug;9(1):89-94. Epub 2006 May 15 doi: 10.1016/j.yebeh.2006.03.013. PMID: 16698323
Severe myoclonic epilepsy in infants--a review based on the Tokyo Women's Medical University series of 84 cases.
Oguni H, Hayashi K, Awaya Y, Fukuyama Y, Osawa M
Brain Dev 2001 Nov;23(7):736-48. doi: 10.1016/s0387-7604(01)00276-5. PMID: 11701288

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • OMIM
      Related records in OMIM
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...