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Benign Pericardial Germ Cell Tumor

MedGen UID:
1636545
•Concept ID:
C4687706
•
Neoplastic Process

Definition

A germ cell tumor that arises from the pericardium. There is no evidence of atypia or metastases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Pericardial Germ Cell Tumor

Professional guidelines

PubMed

Prenatal Diagnosis and Outcome of Intrapericardial Teratoma: Report of Two Clinical Scenarios.
Martínez-García A, Cervantes-Salazar J, Copado-Mendoza DY, Aranda-Fraustro A, Barrera-Valdivieso MA, Pereira-López GI, Calderón-Colmenero J
World J Pediatr Congenit Heart Surg 2023 Jan;14(1):88-90. Epub 2022 Oct 16 doi: 10.1177/21501351221129189. PMID: 36250319
Treatment strategies for pediatric patients with primary cardiac and pericardial tumors: a 30-year review.
Günther T, Schreiber C, Noebauer C, Eicken A, Lange R
Pediatr Cardiol 2008 Nov;29(6):1071-6. Epub 2008 Jul 4 doi: 10.1007/s00246-008-9256-6. PMID: 18600370
Successful surgical management of a prenatally diagnosed intrapericardial teratoma.
Ragupathy R, Nemeth L, Kumaran V, Rajamani G, Krishnamoothy P
Pediatr Surg Int 2003 Dec;19(11):737-9. doi: 10.1007/s00383-003-0969-6. PMID: 14986592

Recent clinical studies

Etiology

Fetal Intrapericardial Teratomas: An Update.
Yuan SM
Z Geburtshilfe Neonatol 2020 Aug;224(4):187-193. Epub 2020 Jun 23 doi: 10.1055/a-1114-6572. PMID: 32575128
Surgical treatment of benign mediastinal teratoma: summary of experience of 108 cases.
Tian Z, Liu H, Li S, Chen Y, Ma D, Han Z, Huang C
J Cardiothorac Surg 2020 Feb 17;15(1):36. doi: 10.1186/s13019-020-1075-8. PMID: 32066478Free PMC Article
Factors affecting the preoperative diagnosis of anterior mediastinal cysts.
Gochi F, Omasa M, Yamada T, Sato M, Menju T, Aoyama A, Sato T, Chen F, Sonobe M, Date H
Gen Thorac Cardiovasc Surg 2015 Jun;63(6):349-53. Epub 2015 Feb 11 doi: 10.1007/s11748-015-0530-2. PMID: 25666659
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Teratomas in childhood.
Bale PM, Painter DM, Cohen D
Pathology 1975 Jul;7(3):209-18. doi: 10.3109/00313027509094411. PMID: 1196679

Diagnosis

Rare mediastinal masses - imaging review.
Patnaik S, Malempati AR, Uppin M, Susarla R
J Cancer Res Ther 2021 Jan-Mar;17(1):13-21. doi: 10.4103/jcrt.JCRT_587_19. PMID: 33723126
Fetal intrapericardial teratomas.
Yuan SM, Lin H
Turk J Pediatr 2019;61(2):153-158. doi: 10.24953/turkjped.2019.02.001. PMID: 31951327
Benign Pericardial Schwannoma: Case Report and Summary of Previously Reported Cases.
Almobarak AA, AlShammari A, Alhomoudi RI, Eshaq AM, Algain SM, Jensen EC, Mohammed S, Al-Kattan K, Kayali Z, AlAmodi AA
Am J Case Rep 2018 Jan 24;19:90-94. doi: 10.12659/ajcr.907408. PMID: 29362352Free PMC Article
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Cardiac tumours in children.
Uzun O, Wilson DG, Vujanic GM, Parsons JM, De Giovanni JV
Orphanet J Rare Dis 2007 Mar 1;2:11. doi: 10.1186/1750-1172-2-11. PMID: 17331235Free PMC Article

Therapy

Surgical treatment of benign mediastinal teratoma: summary of experience of 108 cases.
Tian Z, Liu H, Li S, Chen Y, Ma D, Han Z, Huang C
J Cardiothorac Surg 2020 Feb 17;15(1):36. doi: 10.1186/s13019-020-1075-8. PMID: 32066478Free PMC Article
Surgical resection of a huge ruptured mature mediastinal teratoma.
Acharya MN, De Robertis F, Popov AF, Anastasiou N
Asian Cardiovasc Thorac Ann 2016 Sep;24(7):726-8. Epub 2016 Jul 19 doi: 10.1177/0218492316658847. PMID: 27440933

Prognosis

Prenatal Diagnosis and Outcome of Intrapericardial Teratoma: Report of Two Clinical Scenarios.
Martínez-García A, Cervantes-Salazar J, Copado-Mendoza DY, Aranda-Fraustro A, Barrera-Valdivieso MA, Pereira-López GI, Calderón-Colmenero J
World J Pediatr Congenit Heart Surg 2023 Jan;14(1):88-90. Epub 2022 Oct 16 doi: 10.1177/21501351221129189. PMID: 36250319
Fetal intrapericardial teratomas.
Yuan SM, Lin H
Turk J Pediatr 2019;61(2):153-158. doi: 10.24953/turkjped.2019.02.001. PMID: 31951327
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Cardiac tumours in children.
Uzun O, Wilson DG, Vujanic GM, Parsons JM, De Giovanni JV
Orphanet J Rare Dis 2007 Mar 1;2:11. doi: 10.1186/1750-1172-2-11. PMID: 17331235Free PMC Article
Teratomas in childhood.
Bale PM, Painter DM, Cohen D
Pathology 1975 Jul;7(3):209-18. doi: 10.3109/00313027509094411. PMID: 1196679

Clinical prediction guides

Fetal intrapericardial teratomas.
Yuan SM, Lin H
Turk J Pediatr 2019;61(2):153-158. doi: 10.24953/turkjped.2019.02.001. PMID: 31951327
Mediastinal schwannoma diagnosed preoperatively as a cyst.
Taguchi S, Mori A, Suzuki R, Hasegawa I, Sato H, Sugiura H, Irie R
Tex Heart Inst J 2014 Feb;41(1):76-9. doi: 10.14503/THIJ-12-2760. PMID: 24512408Free PMC Article
Usefulness of magnetic resonance imaging of cardiac and paracardiac masses.
Hoffmann U, Globits S, Schima W, Loewe C, Puig S, Oberhuber G, Frank H
Am J Cardiol 2003 Oct 1;92(7):890-5. doi: 10.1016/s0002-9149(03)00911-1. PMID: 14516903
Unusual primary tumors of the heart.
Vander Salm TJ
Semin Thorac Cardiovasc Surg 2000 Apr;12(2):89-100. doi: 10.1053/ct.2000.5080. PMID: 10807431
Benign neoplasms and cysts of the mediastinum.
Rice TW
Semin Thorac Cardiovasc Surg 1992 Jan;4(1):25-33. PMID: 1550887

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