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Abnormal Growth Hormone

MedGen UID:
163655
•Concept ID:
C0860787
•
Finding

Definition

A laboratory test result which indicates abnormal levels of growth hormone in a biologic specimen. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal Growth Hormone

Professional guidelines

PubMed

Clinical and genetic evaluation of children with short stature of unknown origin.
Zhao Q, Li Y, Shao Q, Zhang C, Kou S, Yang W, Zhang M, Ban B
BMC Med Genomics 2023 Aug 21;16(1):194. doi: 10.1186/s12920-023-01626-4. PMID: 37605180Free PMC Article
Management of fat accumulation in patients with HIV infection.
Falutz J
Curr HIV/AIDS Rep 2011 Sep;8(3):200-8. doi: 10.1007/s11904-011-0087-3. PMID: 21739217
Growth hormone treatment of Russell-Silver syndrome.
Stanhope R, Albanese A, Azcona C
Horm Res 1998;49 Suppl 2:37-40. doi: 10.1159/000053086. PMID: 9730671

Recent clinical studies

Etiology

Clinical and genetic evaluation of children with short stature of unknown origin.
Zhao Q, Li Y, Shao Q, Zhang C, Kou S, Yang W, Zhang M, Ban B
BMC Med Genomics 2023 Aug 21;16(1):194. doi: 10.1186/s12920-023-01626-4. PMID: 37605180Free PMC Article
Management of fat accumulation in patients with HIV infection.
Falutz J
Curr HIV/AIDS Rep 2011 Sep;8(3):200-8. doi: 10.1007/s11904-011-0087-3. PMID: 21739217
Resistance to growth hormone and insulin-like growth factor-I in acidotic rats.
Ordóñez FA, Santos F, Martínez V, García E, Fernández P, Rodríguez J, Fernández M, Alvarez J, Ferrando S
Pediatr Nephrol 2000 Aug;14(8-9):720-5. doi: 10.1007/pl00013425. PMID: 10955915
Growth hormone treatment of Russell-Silver syndrome.
Stanhope R, Albanese A, Azcona C
Horm Res 1998;49 Suppl 2:37-40. doi: 10.1159/000053086. PMID: 9730671
The Gordon Wilson Lecture. Growth hormone replacement in adults and other uses.
Vance ML
Trans Am Clin Climatol Assoc 1998;109:87-96. PMID: 9601130Free PMC Article

Diagnosis

Paediatric Cushing syndrome: a prospective, multisite, observational cohort study.
Tatsi C, Kamilaris C, Keil M, Saidkhodjaeva L, Faucz FR, Chittiboina P, Stratakis CA
Lancet Child Adolesc Health 2024 Jan;8(1):51-62. doi: 10.1016/S2352-4642(23)00264-X. PMID: 38097317
Clinical and genetic evaluation of children with short stature of unknown origin.
Zhao Q, Li Y, Shao Q, Zhang C, Kou S, Yang W, Zhang M, Ban B
BMC Med Genomics 2023 Aug 21;16(1):194. doi: 10.1186/s12920-023-01626-4. PMID: 37605180Free PMC Article
Predicting the probability of abnormal stimulated growth hormone response in children after radiotherapy for brain tumors.
Hua C, Wu S, Chemaitilly W, Lukose RC, Merchant TE
Int J Radiat Oncol Biol Phys 2012 Nov 15;84(4):990-5. Epub 2012 Apr 6 doi: 10.1016/j.ijrobp.2012.01.049. PMID: 22483696Free PMC Article
Abnormal growth hormone release following luteinizing hormone releasing hormone in anorexia nervosa.
Maeda K, Tanimoto K, Chihara K
Jpn J Psychiatry Neurol 1987 Mar;41(1):41-5. doi: 10.1111/j.1440-1819.1987.tb00389.x. PMID: 3114526
Abnormal growth hormone responses to L-dopa and thyrotropin-releasing hormone in patients with acromegaly.
Hanew K, Aida M, Tano T, Yoshinaga K
Tohoku J Exp Med 1977 Mar;121(3):197-206. doi: 10.1620/tjem.121.197. PMID: 404727

Therapy

Traumatic brain injury, abnormal growth hormone secretion, and gut dysbiosis.
Armstrong PA, Venugopal N, Wright TJ, Randolph KM, Batson RD, Yuen KCJ, Masel BE, Sheffield-Moore M, Urban RJ, Pyles RB
Best Pract Res Clin Endocrinol Metab 2023 Dec;37(6):101841. Epub 2023 Nov 19 doi: 10.1016/j.beem.2023.101841. PMID: 38000973
Alterations of the GH/IGF-I Axis and Gut Microbiome after Traumatic Brain Injury: A New Clinical Syndrome?
Yuen KCJ, Masel BE, Reifschneider KL, Sheffield-Moore M, Urban RJ, Pyles RB
J Clin Endocrinol Metab 2020 Sep 1;105(9) doi: 10.1210/clinem/dgaa398. PMID: 32585029
Management of fat accumulation in patients with HIV infection.
Falutz J
Curr HIV/AIDS Rep 2011 Sep;8(3):200-8. doi: 10.1007/s11904-011-0087-3. PMID: 21739217
Growth hormone treatment of Russell-Silver syndrome.
Stanhope R, Albanese A, Azcona C
Horm Res 1998;49 Suppl 2:37-40. doi: 10.1159/000053086. PMID: 9730671
The Gordon Wilson Lecture. Growth hormone replacement in adults and other uses.
Vance ML
Trans Am Clin Climatol Assoc 1998;109:87-96. PMID: 9601130Free PMC Article

Prognosis

Paediatric Cushing syndrome: a prospective, multisite, observational cohort study.
Tatsi C, Kamilaris C, Keil M, Saidkhodjaeva L, Faucz FR, Chittiboina P, Stratakis CA
Lancet Child Adolesc Health 2024 Jan;8(1):51-62. doi: 10.1016/S2352-4642(23)00264-X. PMID: 38097317
A case of growth-hormone staining pituitary adenoma with renal cyst and hepatic cyst: are they related manifestations of a single disease?
Ma J, Liu P
Neuro Endocrinol Lett 2014;35(4):257-61. PMID: 25038593
Predicting the probability of abnormal stimulated growth hormone response in children after radiotherapy for brain tumors.
Hua C, Wu S, Chemaitilly W, Lukose RC, Merchant TE
Int J Radiat Oncol Biol Phys 2012 Nov 15;84(4):990-5. Epub 2012 Apr 6 doi: 10.1016/j.ijrobp.2012.01.049. PMID: 22483696Free PMC Article
The natural course of growth hormone-secreting pituitary adenomas after surgery alone--clinical significance of the growth hormone response to thyrotropin-releasing hormone and luteinizing hormone-releasing hormone.
Mukada K
Neurol Med Chir (Tokyo) 1990 Apr;30(4):251-7. doi: 10.2176/nmc.30.251. PMID: 1696695
Clinical use of pre- and postsurgical evaluation of abnormal GH responses in acromegaly.
Arosio M, Giovanelli MA, Riva E, Nava C, Ambrosi B, Faglia G
J Neurosurg 1983 Sep;59(3):402-8. doi: 10.3171/jns.1983.59.3.0402. PMID: 6411870

Clinical prediction guides

Paediatric Cushing syndrome: a prospective, multisite, observational cohort study.
Tatsi C, Kamilaris C, Keil M, Saidkhodjaeva L, Faucz FR, Chittiboina P, Stratakis CA
Lancet Child Adolesc Health 2024 Jan;8(1):51-62. doi: 10.1016/S2352-4642(23)00264-X. PMID: 38097317
Traumatic brain injury, abnormal growth hormone secretion, and gut dysbiosis.
Armstrong PA, Venugopal N, Wright TJ, Randolph KM, Batson RD, Yuen KCJ, Masel BE, Sheffield-Moore M, Urban RJ, Pyles RB
Best Pract Res Clin Endocrinol Metab 2023 Dec;37(6):101841. Epub 2023 Nov 19 doi: 10.1016/j.beem.2023.101841. PMID: 38000973
The coagulation system in endocrine disorders: a narrative review.
Squizzato A, Gerdes VE, Ageno W, Büller HR
Intern Emerg Med 2007 Jun;2(2):76-83. Epub 2007 Jul 9 doi: 10.1007/s11739-007-0026-X. PMID: 17657422
Effects of growth hormone on glucose and fat metabolism in human subjects.
Jørgensen JO, Møller L, Krag M, Billestrup N, Christiansen JS
Endocrinol Metab Clin North Am 2007 Mar;36(1):75-87. doi: 10.1016/j.ecl.2006.11.005. PMID: 17336735
Resistance to growth hormone and insulin-like growth factor-I in acidotic rats.
Ordóñez FA, Santos F, Martínez V, García E, Fernández P, Rodríguez J, Fernández M, Alvarez J, Ferrando S
Pediatr Nephrol 2000 Aug;14(8-9):720-5. doi: 10.1007/pl00013425. PMID: 10955915

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