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Superficial Basal Cell Carcinoma

MedGen UID:
163678
Concept ID:
C0862889
Neoplastic Process
Synonyms: Multifocal basal cell carcinoma; Superficial basal cell carcinoma
SNOMED CT: Superficial basal cell carcinoma (403914000); Multifocal basal cell carcinoma (403914000)

Definition

A variant of basal cell carcinoma of the skin presenting as erythematous, often multiple patches. Morphologically, it is characterized by the presence of superficial lobules of basaloid cells projecting into the dermis. The basaloid cell lobules are surrounded by myxoid stroma and are usually confined to the papillary dermis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSuperficial Basal Cell Carcinoma

Professional guidelines

PubMed

Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
de Albuquerque IO, Nunes J, Figueiró Longo JP, Muehlmann LA, Azevedo RB
Photodiagnosis Photodyn Ther 2019 Sep;27:428-432. Epub 2019 Jul 23 doi: 10.1016/j.pdpdt.2019.07.017. PMID: 31349099
Alter M, Hillen U, Leiter U, Sachse M, Gutzmer R
J Dtsch Dermatol Ges 2015 Sep;13(9):863-74; quiz 875. doi: 10.1111/ddg.12798. PMID: 26882375

Recent clinical studies

Etiology

Hattier GA, Duffy RF, Finkelstein MJ, Beggs SM, Lee JB
J Dermatolog Treat 2022 Feb;33(1):191-194. Epub 2020 Mar 11 doi: 10.1080/09546634.2020.1737637. PMID: 32116084
Kash N, Silapunt S
Future Oncol 2021 Aug;17(23):3111-3132. Epub 2021 Jun 22 doi: 10.2217/fon-2020-1147. PMID: 34156307
Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
de Albuquerque IO, Nunes J, Figueiró Longo JP, Muehlmann LA, Azevedo RB
Photodiagnosis Photodyn Ther 2019 Sep;27:428-432. Epub 2019 Jul 23 doi: 10.1016/j.pdpdt.2019.07.017. PMID: 31349099
Oldfield V, Keating GM, Perry CM
Am J Clin Dermatol 2005;6(3):195-200; discussion 201-2. doi: 10.2165/00128071-200506030-00006. PMID: 15943496

Diagnosis

Hattier GA, Duffy RF, Finkelstein MJ, Beggs SM, Lee JB
J Dermatolog Treat 2022 Feb;33(1):191-194. Epub 2020 Mar 11 doi: 10.1080/09546634.2020.1737637. PMID: 32116084
Firnhaber JM
Am Fam Physician 2020 Sep 15;102(6):339-346. PMID: 32931212
Alter M, Hillen U, Leiter U, Sachse M, Gutzmer R
J Dtsch Dermatol Ges 2015 Sep;13(9):863-74; quiz 875. doi: 10.1111/ddg.12798. PMID: 26882375
Hussain AA, Themstrup L, Jemec GB
Arch Dermatol Res 2015 Jan;307(1):1-10. Epub 2014 Sep 16 doi: 10.1007/s00403-014-1498-y. PMID: 25223745
Zouboulis CC
Eur J Dermatol 1998 Oct-Nov;8(7):466-74. PMID: 9854156

Therapy

Reiter O, Mimouni I, Dusza S, Halpern AC, Leshem YA, Marghoob AA
J Am Acad Dermatol 2021 Sep;85(3):653-664. Epub 2019 Nov 7 doi: 10.1016/j.jaad.2019.11.008. PMID: 31706938Free PMC Article
de Albuquerque IO, Nunes J, Figueiró Longo JP, Muehlmann LA, Azevedo RB
Photodiagnosis Photodyn Ther 2019 Sep;27:428-432. Epub 2019 Jul 23 doi: 10.1016/j.pdpdt.2019.07.017. PMID: 31349099
Prince GT, Cameron MC, Fathi R, Alkousakis T
Int J Dermatol 2018 Oct;57(10):1259-1264. Epub 2018 Jun 25 doi: 10.1111/ijd.14106. PMID: 30187924
Alter M, Hillen U, Leiter U, Sachse M, Gutzmer R
J Dtsch Dermatol Ges 2015 Sep;13(9):863-74; quiz 875. doi: 10.1111/ddg.12798. PMID: 26882375
Oldfield V, Keating GM, Perry CM
Am J Clin Dermatol 2005;6(3):195-200; discussion 201-2. doi: 10.2165/00128071-200506030-00006. PMID: 15943496

Prognosis

Gupta R, Selinger CI, Ashford B, Chua MST, Clark JR, Damian DL, Jackett LA, James C, Johnson S, Ladwa R, Lambie D, McKenzie C, Tan ST, Scolyer RA
Pathology 2023 Oct;55(6):743-759. Epub 2023 Jul 28 doi: 10.1016/j.pathol.2023.07.003. PMID: 37573165
Zhang YQ, Wang LF, Ni N, Li XL, Zhu AQ, Guo LH, Wang Q, Xu HX
Dermatology 2023;239(4):572-583. Epub 2023 Feb 2 doi: 10.1159/000529448. PMID: 36731445
Gaitanis G, Bassukas ID
J Geriatr Oncol 2019 May;10(3):475-478. Epub 2018 Sep 12 doi: 10.1016/j.jgo.2018.08.012. PMID: 30219274
Hussain AA, Themstrup L, Jemec GB
Arch Dermatol Res 2015 Jan;307(1):1-10. Epub 2014 Sep 16 doi: 10.1007/s00403-014-1498-y. PMID: 25223745
Zouboulis CC
Eur J Dermatol 1998 Oct-Nov;8(7):466-74. PMID: 9854156

Clinical prediction guides

Zhang YQ, Wang LF, Ni N, Li XL, Zhu AQ, Guo LH, Wang Q, Xu HX
Dermatology 2023;239(4):572-583. Epub 2023 Feb 2 doi: 10.1159/000529448. PMID: 36731445
Hattier GA, Duffy RF, Finkelstein MJ, Beggs SM, Lee JB
J Dermatolog Treat 2022 Feb;33(1):191-194. Epub 2020 Mar 11 doi: 10.1080/09546634.2020.1737637. PMID: 32116084
Alique-García S, Company-Quiroga J, Sánchez Campos A, Hernández Núñez A, Borbujo J
Photodiagnosis Photodyn Ther 2019 Jun;26:190-192. Epub 2019 Mar 23 doi: 10.1016/j.pdpdt.2019.03.018. PMID: 30914392
Gaitanis G, Bassukas ID
J Geriatr Oncol 2019 May;10(3):475-478. Epub 2018 Sep 12 doi: 10.1016/j.jgo.2018.08.012. PMID: 30219274
Hussain AA, Themstrup L, Jemec GB
Arch Dermatol Res 2015 Jan;307(1):1-10. Epub 2014 Sep 16 doi: 10.1007/s00403-014-1498-y. PMID: 25223745

Recent systematic reviews

Reiter O, Mimouni I, Dusza S, Halpern AC, Leshem YA, Marghoob AA
J Am Acad Dermatol 2021 Sep;85(3):653-664. Epub 2019 Nov 7 doi: 10.1016/j.jaad.2019.11.008. PMID: 31706938Free PMC Article
Prince GT, Cameron MC, Fathi R, Alkousakis T
J Drugs Dermatol 2018 Mar 1;17(3):274-280. PMID: 29537445
Wat H, Wu DC, Rao J, Goldman MP
Dermatol Surg 2014 Apr;40(4):359-77. Epub 2014 Feb 4 doi: 10.1111/dsu.12424. PMID: 24495252
Roozeboom MH, Arits AH, Nelemans PJ, Kelleners-Smeets NW
Br J Dermatol 2012 Oct;167(4):733-56. Epub 2012 Sep 7 doi: 10.1111/j.1365-2133.2012.11061.x. PMID: 22612571
Bath-Hextall F, Bong J, Perkins W, Williams H
BMJ 2004 Sep 25;329(7468):705. Epub 2004 Sep 13 doi: 10.1136/bmj.38219.515266.AE. PMID: 15364703Free PMC Article

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