U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Oropharyngeal Pain, CTCAE

MedGen UID:
1636823
•Concept ID:
C4554669
•
Finding

Definition

A disorder characterized by a sensation of marked discomfort in the oropharynx. [from NCI]

Recent clinical studies

Etiology

Comparison of Patient- and Practitioner-Reported Toxic Effects Associated With Chemoradiotherapy for Head and Neck Cancer.
Falchook AD, Green R, Knowles ME, Amdur RJ, Mendenhall W, Hayes DN, Grilley-Olson JE, Weiss J, Reeve BB, Mitchell SA, Basch EM, Chera BS
JAMA Otolaryngol Head Neck Surg 2016 Jun 1;142(6):517-23. doi: 10.1001/jamaoto.2016.0656. PMID: 27149571Free PMC Article
Phase 2 Trial of De-intensified Chemoradiation Therapy for Favorable-Risk Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma.
Chera BS, Amdur RJ, Tepper J, Qaqish B, Green R, Aumer SL, Hayes N, Weiss J, Grilley-Olson J, Zanation A, Hackman T, Funkhouser W, Sheets N, Weissler M, Mendenhall W
Int J Radiat Oncol Biol Phys 2015 Dec 1;93(5):976-85. Epub 2015 Aug 22 doi: 10.1016/j.ijrobp.2015.08.033. PMID: 26581135
Developing a CTCAEs patient questionnaire for late toxicity after head and neck radiotherapy.
Ho KF, Farnell DJ, Routledge JA, Burns MP, Sykes AJ, Slevin NJ, Davidson SE
Eur J Cancer 2009 Jul;45(11):1992-8. Epub 2009 May 6 doi: 10.1016/j.ejca.2009.04.010. PMID: 19427196

Therapy

Randomized Phase 3, Double-Blind, Placebo-Controlled Study of Prophylactic Gabapentin for the Reduction of Oral Mucositis Pain During the Treatment of Oropharyngeal Squamous Cell Carcinoma.
Cook A, Modh A, Ali H, Sheqwara J, Chang S, Ghanem T, Momin S, Wu V, Tam S, Money S, Han X, Fakhoury L, Movsas B, Siddiqui F
Int J Radiat Oncol Biol Phys 2022 Mar 15;112(4):926-937. Epub 2021 Nov 20 doi: 10.1016/j.ijrobp.2021.11.012. PMID: 34808255
Comparison of Patient- and Practitioner-Reported Toxic Effects Associated With Chemoradiotherapy for Head and Neck Cancer.
Falchook AD, Green R, Knowles ME, Amdur RJ, Mendenhall W, Hayes DN, Grilley-Olson JE, Weiss J, Reeve BB, Mitchell SA, Basch EM, Chera BS
JAMA Otolaryngol Head Neck Surg 2016 Jun 1;142(6):517-23. doi: 10.1001/jamaoto.2016.0656. PMID: 27149571Free PMC Article
Phase 2 Trial of De-intensified Chemoradiation Therapy for Favorable-Risk Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma.
Chera BS, Amdur RJ, Tepper J, Qaqish B, Green R, Aumer SL, Hayes N, Weiss J, Grilley-Olson J, Zanation A, Hackman T, Funkhouser W, Sheets N, Weissler M, Mendenhall W
Int J Radiat Oncol Biol Phys 2015 Dec 1;93(5):976-85. Epub 2015 Aug 22 doi: 10.1016/j.ijrobp.2015.08.033. PMID: 26581135
A phase 1B/2 study of aldoxorubicin in patients with soft tissue sarcoma.
Chawla SP, Chua VS, Hendifar AF, Quon DV, Soman N, Sankhala KK, Wieland DS, Levitt DJ
Cancer 2015 Feb 15;121(4):570-9. Epub 2014 Oct 13 doi: 10.1002/cncr.29081. PMID: 25312684

Prognosis

Developing a CTCAEs patient questionnaire for late toxicity after head and neck radiotherapy.
Ho KF, Farnell DJ, Routledge JA, Burns MP, Sykes AJ, Slevin NJ, Davidson SE
Eur J Cancer 2009 Jul;45(11):1992-8. Epub 2009 May 6 doi: 10.1016/j.ejca.2009.04.010. PMID: 19427196

Clinical prediction guides

Randomized Phase 3, Double-Blind, Placebo-Controlled Study of Prophylactic Gabapentin for the Reduction of Oral Mucositis Pain During the Treatment of Oropharyngeal Squamous Cell Carcinoma.
Cook A, Modh A, Ali H, Sheqwara J, Chang S, Ghanem T, Momin S, Wu V, Tam S, Money S, Han X, Fakhoury L, Movsas B, Siddiqui F
Int J Radiat Oncol Biol Phys 2022 Mar 15;112(4):926-937. Epub 2021 Nov 20 doi: 10.1016/j.ijrobp.2021.11.012. PMID: 34808255
Comparison of Patient- and Practitioner-Reported Toxic Effects Associated With Chemoradiotherapy for Head and Neck Cancer.
Falchook AD, Green R, Knowles ME, Amdur RJ, Mendenhall W, Hayes DN, Grilley-Olson JE, Weiss J, Reeve BB, Mitchell SA, Basch EM, Chera BS
JAMA Otolaryngol Head Neck Surg 2016 Jun 1;142(6):517-23. doi: 10.1001/jamaoto.2016.0656. PMID: 27149571Free PMC Article
Developing a CTCAEs patient questionnaire for late toxicity after head and neck radiotherapy.
Ho KF, Farnell DJ, Routledge JA, Burns MP, Sykes AJ, Slevin NJ, Davidson SE
Eur J Cancer 2009 Jul;45(11):1992-8. Epub 2009 May 6 doi: 10.1016/j.ejca.2009.04.010. PMID: 19427196

Supplemental Content

Table of contents

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...