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Abnormal P wave

MedGen UID:
1638207
Concept ID:
C4703432
Finding
HPO: HP:0031595

Definition

Any anomaly of the P wave of the EKG, which results from atrial depolarization. The P wave occurs when the sinoatrial node creates an action potential that depolarizes the atria. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal P wave

Professional guidelines

PubMed

Costantino S, Mengozzi A, Velagapudi S, Mohammed SA, Gorica E, Akhmedov A, Mongelli A, Pugliese NR, Masi S, Virdis A, Hülsmeier A, Matter CM, Hornemann T, Melina G, Ruschitzka F, Luscher TF, Paneni F
Cardiovasc Diabetol 2023 Nov 13;22(1):312. doi: 10.1186/s12933-023-02057-2. PMID: 37957697Free PMC Article
Kasap Demir B, Soyaltin E, Alparslan C, Arslansoyu Çamlar S, Demircan T, Yavaşcan Ö, Mutlubaş F, Alaygut D, Karadeniz C
Exp Clin Transplant 2023 Jan;21(1):28-35. Epub 2021 Feb 1 doi: 10.6002/ect.2020.0162. PMID: 33535941
Chen LY, Ribeiro ALP, Platonov PG, Cygankiewicz I, Soliman EZ, Gorenek B, Ikeda T, Vassilikos VP, Steinberg JS, Varma N, Bayés-de-Luna A, Baranchuk A
Circ Arrhythm Electrophysiol 2022 Apr;15(4):e010435. Epub 2022 Mar 25 doi: 10.1161/CIRCEP.121.010435. PMID: 35333097Free PMC Article

Recent clinical studies

Etiology

Berry-Noronha A, Bonavia L, Wilson D, Eranti A, Rasmussen MU, Sajadieh A, Kreimer F, Gotzmann M, Sahathevan R
Eur Stroke J 2023 Sep;8(3):712-721. Epub 2023 May 2 doi: 10.1177/23969873231172559. PMID: 37641552Free PMC Article
Sanna GD, Piga M, Piga A, Falco O, Ponti E, Cauli A, Floris A, Mangoni AA, Casu G, De Luca G, Erre GL; EDRA Study Group
Clin Exp Rheumatol 2023 Jul;41(7):1427-1433. Epub 2023 Jan 2 doi: 10.55563/clinexprheumatol/d9l4lt. PMID: 36622121
Wakatsuki D, Asano T, Mase H, Kurata M, Onuki T, Suzuki H
J Electrocardiol 2022 Jul-Aug;73:1-7. Epub 2022 Apr 26 doi: 10.1016/j.jelectrocard.2022.04.003. PMID: 35524997
Almuwaqqat Z, O'Neal WT, Hammadah M, Lima BB, Bremner JD, Soliman EZ, Shah AJ, Quyyumi AA, Vaccarino V
J Electrocardiol 2020 May-Jun;60:3-7. Epub 2020 Mar 3 doi: 10.1016/j.jelectrocard.2020.02.019. PMID: 32179275Free PMC Article
Lehtonen AO, Puukka P, Varis J, Porthan K, Tikkanen JT, Nieminen MS, Huikuri HV, Anttila I, Nikus K, Kähönen M, Jula A, Niiranen TJ
J Hypertens 2016 May;34(5):959-66. doi: 10.1097/HJH.0000000000000882. PMID: 26886566

Diagnosis

Berry-Noronha A, Bonavia L, Wilson D, Eranti A, Rasmussen MU, Sajadieh A, Kreimer F, Gotzmann M, Sahathevan R
Eur Stroke J 2023 Sep;8(3):712-721. Epub 2023 May 2 doi: 10.1177/23969873231172559. PMID: 37641552Free PMC Article
Kazibwe R, Ahmad MI, Luqman-Arafat TK, Chen H, Yeboah J, Soliman EZ
J Electrocardiol 2023 Jul-Aug;79:100-107. Epub 2023 Apr 3 doi: 10.1016/j.jelectrocard.2023.03.085. PMID: 37030109
Sanna GD, Piga M, Piga A, Falco O, Ponti E, Cauli A, Floris A, Mangoni AA, Casu G, De Luca G, Erre GL; EDRA Study Group
Clin Exp Rheumatol 2023 Jul;41(7):1427-1433. Epub 2023 Jan 2 doi: 10.55563/clinexprheumatol/d9l4lt. PMID: 36622121
Almuwaqqat Z, O'Neal WT, Hammadah M, Lima BB, Bremner JD, Soliman EZ, Shah AJ, Quyyumi AA, Vaccarino V
J Electrocardiol 2020 May-Jun;60:3-7. Epub 2020 Mar 3 doi: 10.1016/j.jelectrocard.2020.02.019. PMID: 32179275Free PMC Article
Maheshwari A, Norby FL, Soliman EZ, Koene RJ, Rooney MR, O'Neal WT, Alonso A, Chen LY
Stroke 2017 Aug;48(8):2060-2065. Epub 2017 Jun 16 doi: 10.1161/STROKEAHA.117.017226. PMID: 28626057Free PMC Article

Therapy

Cheng X, Wang X
Medicine (Baltimore) 2024 Apr 12;103(15):e37582. doi: 10.1097/MD.0000000000037582. PMID: 38608063Free PMC Article
Berry-Noronha A, Bonavia L, Wilson D, Eranti A, Rasmussen MU, Sajadieh A, Kreimer F, Gotzmann M, Sahathevan R
Eur Stroke J 2023 Sep;8(3):712-721. Epub 2023 May 2 doi: 10.1177/23969873231172559. PMID: 37641552Free PMC Article
Chattopadhyay RK, Chousou PA, Mukherjee T, Pugh PJ, Vassiliou VS
PLoS One 2022;17(12):e0278527. Epub 2022 Dec 1 doi: 10.1371/journal.pone.0278527. PMID: 36454918Free PMC Article
Skipina TM, Patel N, Upadhya B, Soliman EZ
Public Health 2022 Apr;205:79-82. Epub 2022 Mar 2 doi: 10.1016/j.puhe.2022.01.026. PMID: 35247863Free PMC Article
Hill CM, Mostafa P, Stuart AG, Thomas DW, Walker RV
Br Dent J 2009 Dec 19;207(12):E23. Epub 2009 Nov 6 doi: 10.1038/sj.bdj.2009.978. PMID: 19893562

Prognosis

Wang Y, Zhang T, Zhang Y, Huang Z, Guo Q, Lan C, Deng L, Liu Y, Wu M, Yu P, Lin L, Liao Y
J Electrocardiol 2024 May-Jun;84:137-144. Epub 2024 Apr 26 doi: 10.1016/j.jelectrocard.2024.04.004. PMID: 38696980
Berry-Noronha A, Bonavia L, Wilson D, Eranti A, Rasmussen MU, Sajadieh A, Kreimer F, Gotzmann M, Sahathevan R
Eur Stroke J 2023 Sep;8(3):712-721. Epub 2023 May 2 doi: 10.1177/23969873231172559. PMID: 37641552Free PMC Article
Lebek S, Wester M, Pec J, Poschenrieder F, Tafelmeier M, Fisser C, Provaznik Z, Schopka S, Debl K, Schmid C, Buchner S, Maier LS, Arzt M, Wagner S
ESC Heart Fail 2021 Oct;8(5):4055-4066. Epub 2021 Jun 30 doi: 10.1002/ehf2.13488. PMID: 34196135Free PMC Article
Maheshwari A, Norby FL, Soliman EZ, Koene RJ, Rooney MR, O'Neal WT, Alonso A, Chen LY
Stroke 2017 Aug;48(8):2060-2065. Epub 2017 Jun 16 doi: 10.1161/STROKEAHA.117.017226. PMID: 28626057Free PMC Article
Kudaiberdiev T, Dzhumagulova A, Joshibayev S, Tilemanbetova K, Imanalieva G
J Electrocardiol 2016 Jan-Feb;49(1):29-36. Epub 2015 Nov 11 doi: 10.1016/j.jelectrocard.2015.10.007. PMID: 26614578

Clinical prediction guides

Berry-Noronha A, Bonavia L, Wilson D, Eranti A, Rasmussen MU, Sajadieh A, Kreimer F, Gotzmann M, Sahathevan R
Eur Stroke J 2023 Sep;8(3):712-721. Epub 2023 May 2 doi: 10.1177/23969873231172559. PMID: 37641552Free PMC Article
Kazibwe R, Ahmad MI, Luqman-Arafat TK, Chen H, Yeboah J, Soliman EZ
J Electrocardiol 2023 Jul-Aug;79:100-107. Epub 2023 Apr 3 doi: 10.1016/j.jelectrocard.2023.03.085. PMID: 37030109
Ahmad MI, Tk LA, Anees MA, Chen LY, Soliman EZ
Am J Cardiol 2022 Oct 1;180:59-64. Epub 2022 Aug 6 doi: 10.1016/j.amjcard.2022.06.051. PMID: 35945040
Wakatsuki D, Asano T, Mase H, Kurata M, Onuki T, Suzuki H
J Electrocardiol 2022 Jul-Aug;73:1-7. Epub 2022 Apr 26 doi: 10.1016/j.jelectrocard.2022.04.003. PMID: 35524997
Lehtonen AO, Puukka P, Varis J, Porthan K, Tikkanen JT, Nieminen MS, Huikuri HV, Anttila I, Nikus K, Kähönen M, Jula A, Niiranen TJ
J Hypertens 2016 May;34(5):959-66. doi: 10.1097/HJH.0000000000000882. PMID: 26886566

Recent systematic reviews

Berry-Noronha A, Bonavia L, Song E, Grose D, Johnson D, Maylin E, Oqueli E, Sahathevan R
Clin Neurol Neurosurg 2024 Feb;237:108164. Epub 2024 Feb 11 doi: 10.1016/j.clineuro.2024.108164. PMID: 38377651
Chattopadhyay RK, Chousou PA, Mukherjee T, Pugh PJ, Vassiliou VS
PLoS One 2022;17(12):e0278527. Epub 2022 Dec 1 doi: 10.1371/journal.pone.0278527. PMID: 36454918Free PMC Article

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