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Alternating hypotropia

MedGen UID:
1638862
Concept ID:
C4703710
Disease or Syndrome
HPO: HP:0500078

Definition

A type of vertical tropia in which, when one eye is fixing, the other eye is deviated downwards. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlternating hypotropia

Recent clinical studies

Etiology

Kim JY, Yang HK, Kim N, Kim MJ, Cho SI, Seong MW, Park SS, Hwang JM
Acta Ophthalmol 2021 Mar;99(2):e274-e280. Epub 2020 Nov 15 doi: 10.1111/aos.14558. PMID: 33191655
Kasem M, Metwally H, El-Adawy IT, Abdelhameed AG
Graefes Arch Clin Exp Ophthalmol 2020 Sep;258(9):1991-1997. Epub 2020 May 27 doi: 10.1007/s00417-020-04742-4. PMID: 32462341
Ocak OB, Inal A, Aygit ED, Celik S, Ocak SY, Karabulut GO, Gokyigit B
J Pediatr Ophthalmol Strabismus 2018 Nov 19;55(6):369-374. Epub 2018 Jul 27 doi: 10.3928/01913913-20180620-04. PMID: 30074607
Kamlesh, Dhiman S, Thacker P, Karothiya B, Goel Y, Rastogi A, Chaudhary R
Int Ophthalmol 2017 Aug;37(4):1009-1016. Epub 2016 Oct 3 doi: 10.1007/s10792-016-0365-6. PMID: 27699607
Struck MC, Larson JC
Strabismus 2015;23(4):176-81. doi: 10.3109/09273972.2015.1099710. PMID: 26669423

Diagnosis

Yamadera K, Kimura A, Okita Y, Mochizuki Y, Gomi F
Graefes Arch Clin Exp Ophthalmol 2024 May;262(5):1641-1646. Epub 2023 Dec 23 doi: 10.1007/s00417-023-06347-z. PMID: 38141057Free PMC Article
Quaranta-Leoni FM, Quaranta-Leoni C, Di Marino M
Orbit 2024 Feb;43(1):33-40. Epub 2023 Mar 1 doi: 10.1080/01676830.2023.2182330. PMID: 36855996
Ocak OB, Inal A, Aygit ED, Celik S, Ocak SY, Karabulut GO, Gokyigit B
J Pediatr Ophthalmol Strabismus 2018 Nov 19;55(6):369-374. Epub 2018 Jul 27 doi: 10.3928/01913913-20180620-04. PMID: 30074607
Paik JS, Yang SW, Park SH
BMC Ophthalmol 2016 Jul 22;16:119. doi: 10.1186/s12886-016-0300-7. PMID: 27449491Free PMC Article
Morrow MJ, Sharpe JA
Ann Neurol 1988 Sep;24(3):390-8. doi: 10.1002/ana.410240307. PMID: 3228274

Therapy

Kasem M, Metwally H, El-Adawy IT, Abdelhameed AG
Graefes Arch Clin Exp Ophthalmol 2020 Sep;258(9):1991-1997. Epub 2020 May 27 doi: 10.1007/s00417-020-04742-4. PMID: 32462341
Akbari MR, Ameri A, Keshtkar Jaafari AR, Mirmohammadsadeghi A
J AAPOS 2016 Apr;20(2):126-130.e1. doi: 10.1016/j.jaapos.2016.01.007. PMID: 27079592
Roper-Hall G, Cruz OA, Espinoza GM, Chung SM
J AAPOS 2013 Jun;17(3):248-52. doi: 10.1016/j.jaapos.2012.12.156. PMID: 23791405
Tejedor J, Díez L
Eur J Ophthalmol 2012 Nov-Dec;22(6):1042-4. Epub 2012 Sep 26 doi: 10.5301/ejo.5000202. PMID: 23097020
Murthy R, Hegde S
J AAPOS 2009 Jun;13(3):312-4. doi: 10.1016/j.jaapos.2009.01.008. PMID: 19541276

Prognosis

Kamlesh, Dhiman S, Thacker P, Karothiya B, Goel Y, Rastogi A, Chaudhary R
Int Ophthalmol 2017 Aug;37(4):1009-1016. Epub 2016 Oct 3 doi: 10.1007/s10792-016-0365-6. PMID: 27699607
Paik JS, Yang SW, Park SH
BMC Ophthalmol 2016 Jul 22;16:119. doi: 10.1186/s12886-016-0300-7. PMID: 27449491Free PMC Article
Akbari MR, Ameri A, Keshtkar Jaafari AR, Mirmohammadsadeghi A
J AAPOS 2016 Apr;20(2):126-130.e1. doi: 10.1016/j.jaapos.2016.01.007. PMID: 27079592
Schild AM, Fricke J, Neugebauer A
Graefes Arch Clin Exp Ophthalmol 2013 Jan;251(1):189-94. Epub 2012 Mar 22 doi: 10.1007/s00417-012-1996-6. PMID: 22434212
Gregersen E, Rindziunski E
Acta Ophthalmol (Copenh) 1993 Jun;71(3):371-6. doi: 10.1111/j.1755-3768.1993.tb07150.x. PMID: 8362637

Clinical prediction guides

Khanna CL, Holmes JM
J AAPOS 2017 Aug;21(4):263-267. Epub 2017 Jun 20 doi: 10.1016/j.jaapos.2017.06.009. PMID: 28642003
Kamlesh, Dhiman S, Thacker P, Karothiya B, Goel Y, Rastogi A, Chaudhary R
Int Ophthalmol 2017 Aug;37(4):1009-1016. Epub 2016 Oct 3 doi: 10.1007/s10792-016-0365-6. PMID: 27699607
Akbari MR, Ameri A, Keshtkar Jaafari AR, Mirmohammadsadeghi A
J AAPOS 2016 Apr;20(2):126-130.e1. doi: 10.1016/j.jaapos.2016.01.007. PMID: 27079592
Donahue SP, Itharat P
J AAPOS 2010 Feb;14(1):42-6. doi: 10.1016/j.jaapos.2009.11.009. PMID: 20227622
Epstein GA, Putterman AM
Ophthalmic Surg 1984 Dec;15(12):971-9. PMID: 6395058

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