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Perfusion Computed Tomography Target Lesion

MedGen UID:
1641488
•Concept ID:
C4684839
•
Disease or Syndrome

Definition

A target lesion that has been identified by computed tomography perfusion imaging. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPerfusion Computed Tomography Target Lesion

Professional guidelines

PubMed

Direct comparison and reproducibility of two segmentation methods for multicompartment dosimetry: round robin study on radioembolization treatment planning in hepatocellular carcinoma.
Lam M, Garin E, Palard-Novello X, Mahvash A, Kappadath C, Haste P, Tann M, Herrmann K, Barbato F, Geller B, Schaefer N, Denys A, Dreher M, Fowers KD, Gates V, Salem R
Eur J Nucl Med Mol Imaging 2023 Dec;51(1):245-257. Epub 2023 Sep 12 doi: 10.1007/s00259-023-06416-9. PMID: 37698645Free PMC Article
Effect of Sex on Clinical Outcome and Imaging after Endovascular Treatment of Large-Vessel Ischemic Stroke.
Demeestere J, Christensen S, Mlynash M, Federau C, Albers GW, Lemmens R, Lansberg MG
J Stroke Cerebrovasc Dis 2021 Feb;30(2):105468. Epub 2020 Nov 21 doi: 10.1016/j.jstrokecerebrovasdis.2020.105468. PMID: 33227604Free PMC Article
The role of imaging in the management of adults with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.
Fouke SJ, Benzinger T, Gibson D, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):457-79. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1908-9. PMID: 26530262

Recent clinical studies

Etiology

Multiphase CT angiography perfusion maps for predicting target mismatch and ischemic lesion volumes.
Chung KJ, Pandey SK, Khaw AV, Lee TY
Sci Rep 2023 Dec 11;13(1):21976. doi: 10.1038/s41598-023-48832-9. PMID: 38081878Free PMC Article
Intracranial Stenting: Angioplasty Basic Technique, Indications, and Sizing: 2-Dimensional Operative Video.
Dossani RH, Waqas M, Cappuzzo JM, Sonig A, Siddiqui AH, Levy EI, Davies JM; Endovascular Neurosurgery Research Group (ENRG)
Oper Neurosurg (Hagerstown) 2021 Jul 15;21(2):E115-E116. doi: 10.1093/ons/opab124. PMID: 33956956Free PMC Article
Reduced Ischemic Lesion Growth with Heparin in Acute Ischemic Stroke.
Rocha EA, Ji R, Ay H, Li Z, Arsava EM, Silva GS, Sorensen AG, Wu O, Singhal AB
J Stroke Cerebrovasc Dis 2019 Jun;28(6):1500-1508. Epub 2019 Mar 29 doi: 10.1016/j.jstrokecerebrovasdis.2019.03.016. PMID: 30935810Free PMC Article
Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke.
Tsai JP, Mlynash M, Christensen S, Kemp S, Kim S, Mishra NK, Federau C, Nogueira RG, Jovin TG, Devlin TG, Akhtar N, Yavagal DR, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Lansberg MG; CRISP Investigators
Stroke 2018 Apr;49(4):952-957. Epub 2018 Mar 16 doi: 10.1161/STROKEAHA.117.018858. PMID: 29581341Free PMC Article
Perfusion computed tomography to assist decision making for stroke thrombolysis.
Bivard A, Levi C, Krishnamurthy V, McElduff P, Miteff F, Spratt NJ, Bateman G, Donnan G, Davis S, Parsons M
Brain 2015 Jul;138(Pt 7):1919-31. Epub 2015 Mar 25 doi: 10.1093/brain/awv071. PMID: 25808369Free PMC Article

Diagnosis

Multiphase CT angiography perfusion maps for predicting target mismatch and ischemic lesion volumes.
Chung KJ, Pandey SK, Khaw AV, Lee TY
Sci Rep 2023 Dec 11;13(1):21976. doi: 10.1038/s41598-023-48832-9. PMID: 38081878Free PMC Article
The incremental value of CCTA-derived myocardial radiomics signature for ischemia diagnosis with reference to CT myocardial perfusion imaging.
Zhu MM, Zhu XM, Lin SS, Dong ST, Liu WY, Zhang JY, Xu Y
Br J Radiol 2023 Aug;96(1148):20220971. Epub 2023 May 25 doi: 10.1259/bjr.20220971. PMID: 37191174Free PMC Article
Effect of Sex on Clinical Outcome and Imaging after Endovascular Treatment of Large-Vessel Ischemic Stroke.
Demeestere J, Christensen S, Mlynash M, Federau C, Albers GW, Lemmens R, Lansberg MG
J Stroke Cerebrovasc Dis 2021 Feb;30(2):105468. Epub 2020 Nov 21 doi: 10.1016/j.jstrokecerebrovasdis.2020.105468. PMID: 33227604Free PMC Article
Early Response of Hepatocellular Carcinoma to Chemoembolization: Volume Computed Tomography Liver Perfusion Imaging as a Short-Term Response Predictor.
Su TH, He W, Jin L, Chen G, Xiao GW
J Comput Assist Tomogr 2017 Mar/Apr;41(2):315-320. doi: 10.1097/RCT.0000000000000511. PMID: 27801695
Intravascular ultrasound-derived morphological predictors of myocardial ischemia assessed by stress myocardial perfusion computed tomography.
Kang SJ, Yang DH, Koo HJ, Yun SC, Lee JG, Kang JW, Lim TH, Mintz GS, Park SW, Kim YH
Catheter Cardiovasc Interv 2017 Jun 1;89(7):E207-E216. Epub 2016 Aug 27 doi: 10.1002/ccd.26710. PMID: 27567025

Therapy

Direct comparison and reproducibility of two segmentation methods for multicompartment dosimetry: round robin study on radioembolization treatment planning in hepatocellular carcinoma.
Lam M, Garin E, Palard-Novello X, Mahvash A, Kappadath C, Haste P, Tann M, Herrmann K, Barbato F, Geller B, Schaefer N, Denys A, Dreher M, Fowers KD, Gates V, Salem R
Eur J Nucl Med Mol Imaging 2023 Dec;51(1):245-257. Epub 2023 Sep 12 doi: 10.1007/s00259-023-06416-9. PMID: 37698645Free PMC Article
Reduced Ischemic Lesion Growth with Heparin in Acute Ischemic Stroke.
Rocha EA, Ji R, Ay H, Li Z, Arsava EM, Silva GS, Sorensen AG, Wu O, Singhal AB
J Stroke Cerebrovasc Dis 2019 Jun;28(6):1500-1508. Epub 2019 Mar 29 doi: 10.1016/j.jstrokecerebrovasdis.2019.03.016. PMID: 30935810Free PMC Article
Intravascular ultrasound-derived morphological predictors of myocardial ischemia assessed by stress myocardial perfusion computed tomography.
Kang SJ, Yang DH, Koo HJ, Yun SC, Lee JG, Kang JW, Lim TH, Mintz GS, Park SW, Kim YH
Catheter Cardiovasc Interv 2017 Jun 1;89(7):E207-E216. Epub 2016 Aug 27 doi: 10.1002/ccd.26710. PMID: 27567025
Perfusion computed tomography to assist decision making for stroke thrombolysis.
Bivard A, Levi C, Krishnamurthy V, McElduff P, Miteff F, Spratt NJ, Bateman G, Donnan G, Davis S, Parsons M
Brain 2015 Jul;138(Pt 7):1919-31. Epub 2015 Mar 25 doi: 10.1093/brain/awv071. PMID: 25808369Free PMC Article
CT perfusion in oncologic imaging: a useful tool?
García-Figueiras R, Goh VJ, Padhani AR, Baleato-González S, Garrido M, León L, Gómez-Caamaño A
AJR Am J Roentgenol 2013 Jan;200(1):8-19. doi: 10.2214/AJR.11.8476. PMID: 23255736

Prognosis

Multiphase CT angiography perfusion maps for predicting target mismatch and ischemic lesion volumes.
Chung KJ, Pandey SK, Khaw AV, Lee TY
Sci Rep 2023 Dec 11;13(1):21976. doi: 10.1038/s41598-023-48832-9. PMID: 38081878Free PMC Article
A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension.
Colebank MJ, Qureshi MU, Rajagopal S, Krasuski RA, Olufsen MS
Am J Physiol Heart Circ Physiol 2021 Aug 1;321(2):H318-H338. Epub 2021 Jun 18 doi: 10.1152/ajpheart.00086.2021. PMID: 34142886Free PMC Article
Reduced Ischemic Lesion Growth with Heparin in Acute Ischemic Stroke.
Rocha EA, Ji R, Ay H, Li Z, Arsava EM, Silva GS, Sorensen AG, Wu O, Singhal AB
J Stroke Cerebrovasc Dis 2019 Jun;28(6):1500-1508. Epub 2019 Mar 29 doi: 10.1016/j.jstrokecerebrovasdis.2019.03.016. PMID: 30935810Free PMC Article
Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke.
Tsai JP, Mlynash M, Christensen S, Kemp S, Kim S, Mishra NK, Federau C, Nogueira RG, Jovin TG, Devlin TG, Akhtar N, Yavagal DR, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Lansberg MG; CRISP Investigators
Stroke 2018 Apr;49(4):952-957. Epub 2018 Mar 16 doi: 10.1161/STROKEAHA.117.018858. PMID: 29581341Free PMC Article
CT perfusion in oncologic imaging: a useful tool?
García-Figueiras R, Goh VJ, Padhani AR, Baleato-González S, Garrido M, León L, Gómez-Caamaño A
AJR Am J Roentgenol 2013 Jan;200(1):8-19. doi: 10.2214/AJR.11.8476. PMID: 23255736

Clinical prediction guides

Multiphase CT angiography perfusion maps for predicting target mismatch and ischemic lesion volumes.
Chung KJ, Pandey SK, Khaw AV, Lee TY
Sci Rep 2023 Dec 11;13(1):21976. doi: 10.1038/s41598-023-48832-9. PMID: 38081878Free PMC Article
A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension.
Colebank MJ, Qureshi MU, Rajagopal S, Krasuski RA, Olufsen MS
Am J Physiol Heart Circ Physiol 2021 Aug 1;321(2):H318-H338. Epub 2021 Jun 18 doi: 10.1152/ajpheart.00086.2021. PMID: 34142886Free PMC Article
Intracranial Stenting: Angioplasty Basic Technique, Indications, and Sizing: 2-Dimensional Operative Video.
Dossani RH, Waqas M, Cappuzzo JM, Sonig A, Siddiqui AH, Levy EI, Davies JM; Endovascular Neurosurgery Research Group (ENRG)
Oper Neurosurg (Hagerstown) 2021 Jul 15;21(2):E115-E116. doi: 10.1093/ons/opab124. PMID: 33956956Free PMC Article
Perfusion computed tomography to assist decision making for stroke thrombolysis.
Bivard A, Levi C, Krishnamurthy V, McElduff P, Miteff F, Spratt NJ, Bateman G, Donnan G, Davis S, Parsons M
Brain 2015 Jul;138(Pt 7):1919-31. Epub 2015 Mar 25 doi: 10.1093/brain/awv071. PMID: 25808369Free PMC Article
CT perfusion in oncologic imaging: a useful tool?
García-Figueiras R, Goh VJ, Padhani AR, Baleato-González S, Garrido M, León L, Gómez-Caamaño A
AJR Am J Roentgenol 2013 Jan;200(1):8-19. doi: 10.2214/AJR.11.8476. PMID: 23255736

Recent systematic reviews

The role of imaging for the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update.
Lundy P, Domino J, Ryken T, Fouke S, McCracken DJ, Ormond DR, Olson JJ
J Neurooncol 2020 Nov;150(2):95-120. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03597-3. PMID: 33215340
The role of imaging in the management of adults with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.
Fouke SJ, Benzinger T, Gibson D, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):457-79. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1908-9. PMID: 26530262

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