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Grade 3 Laryngeal Mucositis, CTCAE

MedGen UID:
1643306
•Concept ID:
C4686343
•
Finding

Definition

Severe pain; severely altered eating/swallowing; medical intervention indicated [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 3 Laryngeal Mucositis, CTCAE

Recent clinical studies

Etiology

Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Whole-Field Sequential Intensity-Modulated Radiotherapy for Local-Regional Advanced Head-and-Neck Squamous Cell Carcinoma.
Refaat T, Choi M, Thomas TO, Bacchus I, Agulnik M, Pelzer HJ, Mellott AL, Rademaker AW, Liu D, Sathiaseelan V, Mittal BB
Am J Clin Oncol 2015 Dec;38(6):588-94. doi: 10.1097/COC.0000000000000001. PMID: 24136140Free PMC Article
Efficacy and safety of combined radiotherapy with EGFR inhibitors and chemotherapy for laryngeal organ preservation in patients with locally advanced hypopharyngeal carcinomas.
Zhang X, Wang J, Wu W, Liu M, Zhao F, Du L, Huang D, Yang S, Ma L
Curr Cancer Drug Targets 2014;14(6):589-98. doi: 10.2174/1568009614666140716115349. PMID: 25039274
Radiotherapy with fraction size of 2.25 Gy in T1-2 laryngeal and hypopharyngeal cancer.
Karasawa K, Kunogi H, Hirai T, Hoji H, Hirowatari H, Izawa H, Ito K, Sasai K, Furuya T, Ozawa S, Matsumoto F, Ito S, Oba S
J Radiat Res 2013 Jul 1;54(4):684-9. Epub 2013 Jan 7 doi: 10.1093/jrr/rrs134. PMID: 23297315Free PMC Article

Therapy

Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Whole-Field Sequential Intensity-Modulated Radiotherapy for Local-Regional Advanced Head-and-Neck Squamous Cell Carcinoma.
Refaat T, Choi M, Thomas TO, Bacchus I, Agulnik M, Pelzer HJ, Mellott AL, Rademaker AW, Liu D, Sathiaseelan V, Mittal BB
Am J Clin Oncol 2015 Dec;38(6):588-94. doi: 10.1097/COC.0000000000000001. PMID: 24136140Free PMC Article
Efficacy and safety of combined radiotherapy with EGFR inhibitors and chemotherapy for laryngeal organ preservation in patients with locally advanced hypopharyngeal carcinomas.
Zhang X, Wang J, Wu W, Liu M, Zhao F, Du L, Huang D, Yang S, Ma L
Curr Cancer Drug Targets 2014;14(6):589-98. doi: 10.2174/1568009614666140716115349. PMID: 25039274
Radiotherapy with fraction size of 2.25 Gy in T1-2 laryngeal and hypopharyngeal cancer.
Karasawa K, Kunogi H, Hirai T, Hoji H, Hirowatari H, Izawa H, Ito K, Sasai K, Furuya T, Ozawa S, Matsumoto F, Ito S, Oba S
J Radiat Res 2013 Jul 1;54(4):684-9. Epub 2013 Jan 7 doi: 10.1093/jrr/rrs134. PMID: 23297315Free PMC Article

Prognosis

Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article

Clinical prediction guides

Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Radiotherapy with fraction size of 2.25 Gy in T1-2 laryngeal and hypopharyngeal cancer.
Karasawa K, Kunogi H, Hirai T, Hoji H, Hirowatari H, Izawa H, Ito K, Sasai K, Furuya T, Ozawa S, Matsumoto F, Ito S, Oba S
J Radiat Res 2013 Jul 1;54(4):684-9. Epub 2013 Jan 7 doi: 10.1093/jrr/rrs134. PMID: 23297315Free PMC Article

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