U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal myeloid cell morphology

MedGen UID:
1644538
Concept ID:
C4703725
Finding
HPO: HP:0020047

Definition

Any structural anomaly of a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. [from HPO]

Professional guidelines

PubMed

Pardanani A
Am J Hematol 2021 Apr 1;96(4):508-525. Epub 2021 Feb 21 doi: 10.1002/ajh.26118. PMID: 33524167
Patnaik MM, Tefferi A
Am J Hematol 2021 Mar 1;96(3):379-394. Epub 2021 Jan 28 doi: 10.1002/ajh.26090. PMID: 33428785
Pardanani A
Am J Hematol 2019 Mar;94(3):363-377. Epub 2019 Jan 2 doi: 10.1002/ajh.25371. PMID: 30536695

Recent clinical studies

Etiology

Calissendorff J, Juhlin CC, Sundin A, Bancos I, Falhammar H
Lancet Diabetes Endocrinol 2021 Nov;9(11):767-775. Epub 2021 Aug 24 doi: 10.1016/S2213-8587(21)00178-9. PMID: 34450092Free PMC Article
Wu X, Liu Y, Jin S, Wang M, Jiao Y, Yang B, Lu X, Ji X, Fei Y, Yang H, Zhao L, Chen H, Zhang Y, Li H, Lipsky PE, Tsokos GC, Bai F, Zhang X
Nat Commun 2021 Aug 17;12(1):4977. doi: 10.1038/s41467-021-25246-7. PMID: 34404786Free PMC Article
Gan RWC, Moustafa A, Turner K, Knight L
Acta Otolaryngol 2021 Jan;141(1):85-88. Epub 2020 Oct 14 doi: 10.1080/00016489.2020.1821246. PMID: 33393421
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I
Curr Hematol Malig Rep 2016 Oct;11(5):333-41. doi: 10.1007/s11899-016-0338-x. PMID: 27510823Free PMC Article
Khwaja A, Bjorkholm M, Gale RE, Levine RL, Jordan CT, Ehninger G, Bloomfield CD, Estey E, Burnett A, Cornelissen JJ, Scheinberg DA, Bouscary D, Linch DC
Nat Rev Dis Primers 2016 Mar 10;2:16010. doi: 10.1038/nrdp.2016.10. PMID: 27159408

Diagnosis

Teti A, Teitelbaum SL
Bone 2019 Feb;119:71-81. Epub 2018 Mar 6 doi: 10.1016/j.bone.2018.03.002. PMID: 29522883
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I
Curr Hematol Malig Rep 2016 Oct;11(5):333-41. doi: 10.1007/s11899-016-0338-x. PMID: 27510823Free PMC Article
Khwaja A, Bjorkholm M, Gale RE, Levine RL, Jordan CT, Ehninger G, Bloomfield CD, Estey E, Burnett A, Cornelissen JJ, Scheinberg DA, Bouscary D, Linch DC
Nat Rev Dis Primers 2016 Mar 10;2:16010. doi: 10.1038/nrdp.2016.10. PMID: 27159408
Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M, Vardiman JW
Blood 2016 May 19;127(20):2391-405. Epub 2016 Apr 11 doi: 10.1182/blood-2016-03-643544. PMID: 27069254
Chatterjee T, Choudhry VP
Indian J Pediatr 2013 Sep;80(9):764-71. Epub 2013 Aug 3 doi: 10.1007/s12098-013-1130-8. PMID: 23912822

Therapy

Pemmaraju N, Sweet KL, Stein AS, Wang ES, Rizzieri DA, Vasu S, Rosenblat TL, Brooks CL, Habboubi N, Mughal TI, Kantarjian H, Konopleva M, Lane AA
J Clin Oncol 2022 Sep 10;40(26):3032-3036. Epub 2022 Jul 12 doi: 10.1200/JCO.22.00034. PMID: 35820082Free PMC Article
Hack SP, Zhu AX, Wang Y
Front Immunol 2020;11:598877. Epub 2020 Nov 5 doi: 10.3389/fimmu.2020.598877. PMID: 33250900Free PMC Article
Guo J, Ren R, Sun K, Yao X, Lin J, Wang G, Guo Z, Xu T, Guo F
Cell Death Dis 2020 Oct 13;11(10):847. doi: 10.1038/s41419-020-03046-z. PMID: 33051453Free PMC Article
Almosailleakh M, Schwaller J
Int J Mol Sci 2019 Jan 21;20(2) doi: 10.3390/ijms20020453. PMID: 30669675Free PMC Article
Craig VJ, Zhang L, Hagood JS, Owen CA
Am J Respir Cell Mol Biol 2015 Nov;53(5):585-600. doi: 10.1165/rcmb.2015-0020TR. PMID: 26121236Free PMC Article

Prognosis

Shahrabi S, Maleknia M, Tavakolifar Y, D Zayeri Z, Saki N
Leuk Lymphoma 2019 Dec;60(14):3363-3374. Epub 2019 Jun 19 doi: 10.1080/10428194.2019.1630622. PMID: 31213100
Wagner J, Rapsomaniki MA, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, Rees M, Ramaswamy A, Muenst S, Soysal SD, Jacobs A, Windhager J, Silina K, van den Broek M, Dedes KJ, Rodríguez Martínez M, Weber WP, Bodenmiller B
Cell 2019 May 16;177(5):1330-1345.e18. Epub 2019 Apr 11 doi: 10.1016/j.cell.2019.03.005. PMID: 30982598Free PMC Article
Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M, Vardiman JW
Blood 2016 May 19;127(20):2391-405. Epub 2016 Apr 11 doi: 10.1182/blood-2016-03-643544. PMID: 27069254
Chatterjee T, Choudhry VP
Indian J Pediatr 2013 Sep;80(9):764-71. Epub 2013 Aug 3 doi: 10.1007/s12098-013-1130-8. PMID: 23912822
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA
Nature 2006 Aug 17;442(7104):818-22. Epub 2006 Jul 16 doi: 10.1038/nature04980. PMID: 16862118

Clinical prediction guides

Zoi K, Cross NC
J Clin Oncol 2017 Mar 20;35(9):947-954. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.70.7968. PMID: 28297629
Collins MH, Martin LJ, Alexander ES, Boyd JT, Sheridan R, He H, Pentiuk S, Putnam PE, Abonia JP, Mukkada VA, Franciosi JP, Rothenberg ME
Dis Esophagus 2017 Feb 1;30(3):1-8. doi: 10.1111/dote.12470. PMID: 26857345Free PMC Article
Ng SW, Mitchell A, Kennedy JA, Chen WC, McLeod J, Ibrahimova N, Arruda A, Popescu A, Gupta V, Schimmer AD, Schuh AC, Yee KW, Bullinger L, Herold T, Görlich D, Büchner T, Hiddemann W, Berdel WE, Wörmann B, Cheok M, Preudhomme C, Dombret H, Metzeler K, Buske C, Löwenberg B, Valk PJ, Zandstra PW, Minden MD, Dick JE, Wang JC
Nature 2016 Dec 15;540(7633):433-437. Epub 2016 Dec 7 doi: 10.1038/nature20598. PMID: 27926740
Chatterjee T, Choudhry VP
Indian J Pediatr 2013 Sep;80(9):764-71. Epub 2013 Aug 3 doi: 10.1007/s12098-013-1130-8. PMID: 23912822
Popovic PJ, Zeh HJ 3rd, Ochoa JB
J Nutr 2007 Jun;137(6 Suppl 2):1681S-1686S. doi: 10.1093/jn/137.6.1681S. PMID: 17513447

Recent systematic reviews

Zhao J, Dong Y, Zhang Y, Wang J, Wang Z
Adv Drug Deliv Rev 2022 Dec;191:114585. Epub 2022 Oct 21 doi: 10.1016/j.addr.2022.114585. PMID: 36273512
Shi Y, Wang C
Clin Immunol 2022 Apr;237:108982. Epub 2022 Mar 17 doi: 10.1016/j.clim.2022.108982. PMID: 35307610
Scappaticcio L, Maiorino MI, Maio A, Esposito K, Bellastella G
Clin Endocrinol (Oxf) 2021 Mar;94(3):473-483. Epub 2020 Sep 1 doi: 10.1111/cen.14313. PMID: 32799342
Alhatem A, Patel N, Lambert WC, Heller DS
J Low Genit Tract Dis 2019 Jul;23(3):235-240. doi: 10.1097/LGT.0000000000000478. PMID: 31149956
Satgé D, Nishi M, Sirvent N, Vekemans M
Am J Med Genet C Semin Med Genet 2016 Sep;172(3):296-306. Epub 2016 Jul 30 doi: 10.1002/ajmg.c.31511. PMID: 27474103

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...