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Abnormal second heart sound

MedGen UID:
1644817
•Concept ID:
C4703468
•
Finding
HPO: HP:0031661

Definition

Any anomaly of the second heart sound (S2), which is produced by aortic (A2) and pulmonic (P2) valve closure. The A2-P2 interval normally increases with inspiration and narrows with expiration. [from HPO]

Professional guidelines

PubMed

Clinical features and management of chronic thromboembolic pulmonary hypertension in Thai.
Sompradeekul S, Minipan M
J Med Assoc Thai 2010 Jan;93 Suppl 1:S79-85. PMID: 20364561
Diagnosis and management of acyanotic heart disease: part II -- left-to-right shunt lesions.
Syamasundar Rao P
Indian J Pediatr 2005 Jun;72(6):503-12. doi: 10.1007/BF02724429. PMID: 15985740
Cross-sectional echocardiographic assessment of atrioventricular septal defect: basic morphology and preoperative risk factors.
Smallhorn JF
Echocardiography 2001 Jul;18(5):415-32. doi: 10.1046/j.1540-8175.2001.00415.x. PMID: 11466155

Recent clinical studies

Etiology

Clinical and haemodynamic features in relation to severity of aortic stenosis in adults.
Danielsen R, Nordrehaug JE, Vik-Mo H
Eur Heart J 1991 Jul;12(7):791-5. doi: 10.1093/eurheartj/12.7.791. PMID: 1889444

Diagnosis

Cardinal clinical signs in the differentiation of heart murmurs in children.
McCrindle BW, Shaffer KM, Kan JS, Zahka KG, Rowe SA, Kidd L
Arch Pediatr Adolesc Med 1996 Feb;150(2):169-74. doi: 10.1001/archpedi.1996.02170270051007. PMID: 8556121
Abnormal second heart sound in hypoplastic right heart complex.
Sanyal SK, Terrell W Jr, Tierney RC
Indian Heart J 1976 Oct;28(4):256-9. PMID: 1022673

Prognosis

Cardinal clinical signs in the differentiation of heart murmurs in children.
McCrindle BW, Shaffer KM, Kan JS, Zahka KG, Rowe SA, Kidd L
Arch Pediatr Adolesc Med 1996 Feb;150(2):169-74. doi: 10.1001/archpedi.1996.02170270051007. PMID: 8556121
Clinical and haemodynamic features in relation to severity of aortic stenosis in adults.
Danielsen R, Nordrehaug JE, Vik-Mo H
Eur Heart J 1991 Jul;12(7):791-5. doi: 10.1093/eurheartj/12.7.791. PMID: 1889444

Clinical prediction guides

Cardinal clinical signs in the differentiation of heart murmurs in children.
McCrindle BW, Shaffer KM, Kan JS, Zahka KG, Rowe SA, Kidd L
Arch Pediatr Adolesc Med 1996 Feb;150(2):169-74. doi: 10.1001/archpedi.1996.02170270051007. PMID: 8556121
Clinical and haemodynamic features in relation to severity of aortic stenosis in adults.
Danielsen R, Nordrehaug JE, Vik-Mo H
Eur Heart J 1991 Jul;12(7):791-5. doi: 10.1093/eurheartj/12.7.791. PMID: 1889444

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