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Metastatic Non-Small Cell Carcinoma

MedGen UID:
1647641
•Concept ID:
C4720862
•
Neoplastic Process
Synonym: Metastatic non-small cell carcinoma
SNOMED CT: Metastatic non-small cell carcinoma (40861000146101)

Definition

Non-small cell carcinoma that has spread from its original site of growth to another anatomic site. [from NCI]

Professional guidelines

PubMed

Treatment at Integrated Centers Might Bridge the Academic-Community Survival Gap in Patients With Metastatic Non-Small Cell Carcinoma of the Lung.
Ramalingam S, Dinan MA, Crawford J
Clin Lung Cancer 2021 Jul;22(4):e646-e653. Epub 2021 Jan 7 doi: 10.1016/j.cllc.2020.12.013. PMID: 33582071
Survival of Contemporary Patients With Non-metastatic Small-cell Carcinoma of Urinary Bladder, According to Alternative Treatment Modalities.
Luzzago S, Palumbo C, Rosiello G, Knipper S, Pecoraro A, Nazzani S, Tian Z, Musi G, Montanari E, Shariat SF, Saad F, Briganti A, de Cobelli O, Karakiewicz PI
Clin Genitourin Cancer 2020 Aug;18(4):e450-e456. Epub 2019 Dec 13 doi: 10.1016/j.clgc.2019.12.001. PMID: 32146153

Recent clinical studies

Etiology

Treatment at Integrated Centers Might Bridge the Academic-Community Survival Gap in Patients With Metastatic Non-Small Cell Carcinoma of the Lung.
Ramalingam S, Dinan MA, Crawford J
Clin Lung Cancer 2021 Jul;22(4):e646-e653. Epub 2021 Jan 7 doi: 10.1016/j.cllc.2020.12.013. PMID: 33582071
Effect of ionizing radiation on partial seizures attributable to malignant cerebral tumors.
Chalifoux R, Elisevich K
Stereotact Funct Neurosurg 1996-1997;67(3-4):169-82. doi: 10.1159/000099446. PMID: 9311074
Etoposide (VP-16) and cisplatin at maximum tolerated dose in non-small cell lung carcinoma: a Cancer and Leukemia Group B study.
Muscato JJ, Cirrincione C, Clamon G, Perry MC, Omura G, Berkowitz I, Reid T, Herndon JE 2nd, Green MR
Lung Cancer 1995 Dec;13(3):285-94. doi: 10.1016/0169-5002(95)00501-3. PMID: 8719068
Phase II trial and cost analysis of fazarabine in advanced non-small cell carcinoma of the lung: a Southwest Oncology Group study.
Williamson SK, Crowley JJ, Livingston RB, Panella TJ, Goodwin JW
Invest New Drugs 1995;13(1):67-71. doi: 10.1007/BF02614223. PMID: 7499111
Cisplatin and vinblastine chemotherapy for metastatic non-small cell carcinoma followed by irradiation in patients with regional disease.
Blum RH, Cooper J, Schmidt AM, Ashinoff R, Collins A, Wernz JC, Speyer JL, Boyd A, Muggia FM
Cancer Treat Rep 1986 Mar;70(3):333-7. PMID: 3955544

Diagnosis

Intussusception secondary to a solitary peritoneal lung metastasis.
Wou C, Sharp E, Johnson L
BMJ Case Rep 2013 Apr 22;2013 doi: 10.1136/bcr-2012-008370. PMID: 23608839Free PMC Article
Blinded prospective comparison of the performance of 22-gauge and 25-gauge needles in endoscopic ultrasound-guided fine needle aspiration of the pancreas and peri-pancreatic lesions.
Lee JH, Stewart J, Ross WA, Anandasabapathy S, Xiao L, Staerkel G
Dig Dis Sci 2009 Oct;54(10):2274-81. Epub 2009 Aug 11 doi: 10.1007/s10620-009-0906-1. PMID: 19669880
Endoscopic ultrasound-guided fine-needle aspiration of lymph nodes: the Hennepin County Medical Center experience.
Stelow EB, Lai R, Bardales RH, Mallery S, Linzie BM, Crary G, Stanley MW
Diagn Cytopathol 2004 May;30(5):301-6. doi: 10.1002/dc.10405. PMID: 15108226
Effect of ionizing radiation on partial seizures attributable to malignant cerebral tumors.
Chalifoux R, Elisevich K
Stereotact Funct Neurosurg 1996-1997;67(3-4):169-82. doi: 10.1159/000099446. PMID: 9311074
Chemotherapy of metastatic non-small cell carcinoma of the lung.
Ruckdeschel JC
Hematol Oncol 1992 Jan-Feb;10(1):25-30. doi: 10.1002/hon.2900100106. PMID: 1314217

Therapy

Blinded prospective comparison of the performance of 22-gauge and 25-gauge needles in endoscopic ultrasound-guided fine needle aspiration of the pancreas and peri-pancreatic lesions.
Lee JH, Stewart J, Ross WA, Anandasabapathy S, Xiao L, Staerkel G
Dig Dis Sci 2009 Oct;54(10):2274-81. Epub 2009 Aug 11 doi: 10.1007/s10620-009-0906-1. PMID: 19669880
Phase II trial of pyrazoloacridine in advanced non-small cell carcinoma of the lung--a Kansas Cancer Institute and Thompson Cancer Survival Center Study.
Bastasch M, Panella TJ, Kretzschmer SL, Graham D, Mayo M, Williamson S
Invest New Drugs 2002 Aug;20(3):339-42. doi: 10.1023/a:1016293527755. PMID: 12201497
Etoposide (VP-16) and cisplatin at maximum tolerated dose in non-small cell lung carcinoma: a Cancer and Leukemia Group B study.
Muscato JJ, Cirrincione C, Clamon G, Perry MC, Omura G, Berkowitz I, Reid T, Herndon JE 2nd, Green MR
Lung Cancer 1995 Dec;13(3):285-94. doi: 10.1016/0169-5002(95)00501-3. PMID: 8719068
Phase II trial and cost analysis of fazarabine in advanced non-small cell carcinoma of the lung: a Southwest Oncology Group study.
Williamson SK, Crowley JJ, Livingston RB, Panella TJ, Goodwin JW
Invest New Drugs 1995;13(1):67-71. doi: 10.1007/BF02614223. PMID: 7499111
Cisplatin and vinblastine chemotherapy for metastatic non-small cell carcinoma followed by irradiation in patients with regional disease.
Blum RH, Cooper J, Schmidt AM, Ashinoff R, Collins A, Wernz JC, Speyer JL, Boyd A, Muggia FM
Cancer Treat Rep 1986 Mar;70(3):333-7. PMID: 3955544

Prognosis

Treatment at Integrated Centers Might Bridge the Academic-Community Survival Gap in Patients With Metastatic Non-Small Cell Carcinoma of the Lung.
Ramalingam S, Dinan MA, Crawford J
Clin Lung Cancer 2021 Jul;22(4):e646-e653. Epub 2021 Jan 7 doi: 10.1016/j.cllc.2020.12.013. PMID: 33582071
Intussusception secondary to a solitary peritoneal lung metastasis.
Wou C, Sharp E, Johnson L
BMJ Case Rep 2013 Apr 22;2013 doi: 10.1136/bcr-2012-008370. PMID: 23608839Free PMC Article
Non-small-cell lung cancer with nonfamilial diffuse palmoplantar keratoderma.
Engin H, Akdogan A, Altundag O, Kars A, Güler N
J Exp Clin Cancer Res 2002 Mar;21(1):45-7. PMID: 12071528
Etoposide (VP-16) and cisplatin at maximum tolerated dose in non-small cell lung carcinoma: a Cancer and Leukemia Group B study.
Muscato JJ, Cirrincione C, Clamon G, Perry MC, Omura G, Berkowitz I, Reid T, Herndon JE 2nd, Green MR
Lung Cancer 1995 Dec;13(3):285-94. doi: 10.1016/0169-5002(95)00501-3. PMID: 8719068
Chemotherapy of metastatic non-small cell carcinoma of the lung.
Ruckdeschel JC
Hematol Oncol 1992 Jan-Feb;10(1):25-30. doi: 10.1002/hon.2900100106. PMID: 1314217

Clinical prediction guides

Effect of ionizing radiation on partial seizures attributable to malignant cerebral tumors.
Chalifoux R, Elisevich K
Stereotact Funct Neurosurg 1996-1997;67(3-4):169-82. doi: 10.1159/000099446. PMID: 9311074
Antibody guided targeting of non-small cell lung cancer using 111In-labeled HMFG1 F(ab')2 fragments.
Kalofonos HP, Sivolapenko GB, Courtenay-Luck NS, Snook DE, Hooker GR, Winter R, McKenzie CG, Taylor-Papadimitriou JJ, Lavender PJ, Epenetos AA
Cancer Res 1988 Apr 1;48(7):1977-84. PMID: 2832056

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