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Abnormal mean corpuscular volume

MedGen UID:
1648289
•Concept ID:
C0853655
•
Finding
Synonyms: Abnormal erythrocyte volume; Abnormal MCV
 
HPO: HP:0025065

Definition

A deviation from normal of the mean corpuscular volume, or mean cell volume (MCV) of red blood cells, usually taken to be 80 to 100 femtoliters. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal mean corpuscular volume

Professional guidelines

PubMed

Compound Heterozygosity for Hb Adana (HBA2: c.179G>A) and the -α(3.7)/αα Thalassemia Deletion in Greece: Clinical Phenotype and Genetic Counseling.
Theodoridou S, Teli A, Yfanti E, Vyzantiadis TA, Theodoridis T, Economou M
Hemoglobin 2018 Mar;42(2):129-131. Epub 2018 Jul 20 doi: 10.1080/03630269.2018.1466711. PMID: 30025477
Secondary polycythaemia: its causes, effects and treatment.
Harrison BD, Stokes TC
Br J Dis Chest 1982 Oct;76(4):313-40. doi: 10.1016/0007-0971(82)90067-5. PMID: 6758830
Alpha thalassemia screening in neonates by mean corpuscular volume and mean corpuscular hemoglobin determination.
Schmaier AH, Maurer HM, Johnston CL, Scott RB
J Pediatr 1973 Nov;83(5):794-7. doi: 10.1016/s0022-3476(73)80371-3. PMID: 4742572

Recent clinical studies

Etiology

The prognostic impact of preoperative mean corpuscular volume in colorectal cancer.
Nakamura K, Seishima R, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y
Jpn J Clin Oncol 2022 May 31;52(6):562-570. doi: 10.1093/jjco/hyac023. PMID: 35253057
Prevalence of preoperative anemia, abnormal mean corpuscular volume and red cell distribution width among surgical patients in Singapore, and their influence on one year mortality.
Sim YE, Wee HE, Ang AL, Ranjakunalan N, Ong BC, Abdullah HR
PLoS One 2017;12(8):e0182543. Epub 2017 Aug 4 doi: 10.1371/journal.pone.0182543. PMID: 28777814Free PMC Article

Prognosis

The prognostic impact of preoperative mean corpuscular volume in colorectal cancer.
Nakamura K, Seishima R, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y
Jpn J Clin Oncol 2022 May 31;52(6):562-570. doi: 10.1093/jjco/hyac023. PMID: 35253057
Prevalence of preoperative anemia, abnormal mean corpuscular volume and red cell distribution width among surgical patients in Singapore, and their influence on one year mortality.
Sim YE, Wee HE, Ang AL, Ranjakunalan N, Ong BC, Abdullah HR
PLoS One 2017;12(8):e0182543. Epub 2017 Aug 4 doi: 10.1371/journal.pone.0182543. PMID: 28777814Free PMC Article

Clinical prediction guides

The prognostic impact of preoperative mean corpuscular volume in colorectal cancer.
Nakamura K, Seishima R, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y
Jpn J Clin Oncol 2022 May 31;52(6):562-570. doi: 10.1093/jjco/hyac023. PMID: 35253057
Prevalence of preoperative anemia, abnormal mean corpuscular volume and red cell distribution width among surgical patients in Singapore, and their influence on one year mortality.
Sim YE, Wee HE, Ang AL, Ranjakunalan N, Ong BC, Abdullah HR
PLoS One 2017;12(8):e0182543. Epub 2017 Aug 4 doi: 10.1371/journal.pone.0182543. PMID: 28777814Free PMC Article

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