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Recurrent Prostate Acinar Adenocarcinoma

MedGen UID:
1648624
•Concept ID:
C4727358
•
Neoplastic Process

Definition

The reemergence of prostate acinar adenocarcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Prostate Acinar Adenocarcinoma

Professional guidelines

PubMed

Surgical management of recurrent genitourinary malignancies.
Greenberg RE, Charles RS, Samaha AM, Chelsky M, Rosen S
Semin Oncol 1993 Oct;20(5):473-92. PMID: 8211196

Recent clinical studies

Etiology

Intraductal Carcinoma of the Prostate without High-Grade Invasive Adenocarcinoma: Report of Two Cases and Review of the Literature.
Ortiz-Rey JA, Bellas-Pereira A, San Miguel-Fraile P, Morellón-Baquera R, Domínguez-Arístegui P, González-Carreró Fojón J
Arch Esp Urol 2022 Nov;75(9):738-745. doi: 10.56434/j.arch.esp.urol.20227509.108. PMID: 36472055
Prostatic Ductal Adenocarcinoma Controlled for Tumor Grade, Stage, and Margin Status Does Not Independently Influence the Likelihood of Biochemical Recurrence in Localized Prostate Cancer After Radical Prostatectomy.
Kryvenko ON, Iakymenko OA, De Lima Guido LP, Bhattu AS, Merhe A, Mouzannar A, Briski LM, Oymagil I, Lugo I, Nemov I, Ritch CR, Kava BR, Punnen S, Jorda M, Parekh DJ, Gonzalgo ML
Arch Pathol Lab Med 2022 Aug 1;146(8):1012-1017. doi: 10.5858/arpa.2021-0048-OA. PMID: 34739539
Ductal variant prostate carcinoma is associated with a significantly shorter metastasis-free survival.
Chow K, Bedő J, Ryan A, Agarwal D, Bolton D, Chan Y, Dundee P, Frydenberg M, Furrer MA, Goad J, Gyomber D, Hanegbi U, Harewood L, King D, Lamb AD, Lawrentschuk N, Liodakis P, Moon D, Murphy DG, Peters JS, Ruljancich P, Verrill CL, Webb D, Wong LM, Zargar H, Costello AJ, Papenfuss AT, Hovens CM, Corcoran NM
Eur J Cancer 2021 May;148:440-450. Epub 2021 Mar 5 doi: 10.1016/j.ejca.2020.12.030. PMID: 33678516
High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate.
Zhou M
Mod Pathol 2018 Jan;31(S1):S71-79. doi: 10.1038/modpathol.2017.138. PMID: 29297491
Ductal adenocarcinoma of the prostate: Clinical and biological profiles.
Vinceneux A, Bruyère F, Haillot O, Charles T, de la Taille A, Salomon L, Allory Y, Ouzaid I, Choudat L, Rouprêt M, Comperat E, Houede N, Beauval JB, Vourc'h P, Fromont G
Prostate 2017 Sep;77(12):1242-1250. Epub 2017 Jul 12 doi: 10.1002/pros.23383. PMID: 28699202

Diagnosis

Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report.
Shi Q, Zhou Y, Wang L
Medicine (Baltimore) 2023 Nov 24;102(47):e36151. doi: 10.1097/MD.0000000000036151. PMID: 38013382Free PMC Article
Primary prostate cancer synchronous with renal cell carcinoma: clinical experience and literature review.
Li ZY, Ying CC, Wan ZH, Wang ZS, Li GH, Chen L, Guo YL
Rom J Morphol Embryol 2020 Apr-Jun;61(2):555-561. doi: 10.47162/RJME.61.2.27. PMID: 33544809Free PMC Article
HoxB13 expression in ductal type adenocarcinoma of prostate: clinicopathologic characteristics and its utility as potential diagnostic marker.
Park CK, Shin SJ, Cho YA, Joo JW, Cho NH
Sci Rep 2019 Dec 27;9(1):20205. doi: 10.1038/s41598-019-56657-8. PMID: 31882852Free PMC Article
High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate.
Zhou M
Mod Pathol 2018 Jan;31(S1):S71-79. doi: 10.1038/modpathol.2017.138. PMID: 29297491
Ductal adenocarcinoma of the prostate: Clinical and biological profiles.
Vinceneux A, Bruyère F, Haillot O, Charles T, de la Taille A, Salomon L, Allory Y, Ouzaid I, Choudat L, Rouprêt M, Comperat E, Houede N, Beauval JB, Vourc'h P, Fromont G
Prostate 2017 Sep;77(12):1242-1250. Epub 2017 Jul 12 doi: 10.1002/pros.23383. PMID: 28699202

Therapy

Incidental Detection of Lung Adenocarcinoma Presenting as an Anterior Mediastinal Mass on 18F-Fluciclovine PET/CT in a Patient With Primary Prostate Cancer.
Abiodun-Ojo OA, Akintayo AA, Sica GL, Alemozaffar M, Schuster DM
Clin Nucl Med 2020 Dec;45(12):e525-e527. doi: 10.1097/RLU.0000000000003207. PMID: 32701811Free PMC Article
Metachronous triple primary neoplasms with primary prostate cancer, lung cancer, and colon cancer: A case report.
Feng Y, Zhong M, Zeng S, Xiao D, Liu Y
Medicine (Baltimore) 2018 Jun;97(26):e11332. doi: 10.1097/MD.0000000000011332. PMID: 29953024Free PMC Article
Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation.
Lipianskaya J, Cohen A, Chen CJ, Hsia E, Squires J, Li Z, Zhang Y, Li W, Chen X, Xu H, Huang J
Asian J Androl 2014 Jul-Aug;16(4):541-4. doi: 10.4103/1008-682X.123669. PMID: 24589459Free PMC Article

Prognosis

Prostatic Ductal Adenocarcinoma Controlled for Tumor Grade, Stage, and Margin Status Does Not Independently Influence the Likelihood of Biochemical Recurrence in Localized Prostate Cancer After Radical Prostatectomy.
Kryvenko ON, Iakymenko OA, De Lima Guido LP, Bhattu AS, Merhe A, Mouzannar A, Briski LM, Oymagil I, Lugo I, Nemov I, Ritch CR, Kava BR, Punnen S, Jorda M, Parekh DJ, Gonzalgo ML
Arch Pathol Lab Med 2022 Aug 1;146(8):1012-1017. doi: 10.5858/arpa.2021-0048-OA. PMID: 34739539
Ductal variant prostate carcinoma is associated with a significantly shorter metastasis-free survival.
Chow K, Bedő J, Ryan A, Agarwal D, Bolton D, Chan Y, Dundee P, Frydenberg M, Furrer MA, Goad J, Gyomber D, Hanegbi U, Harewood L, King D, Lamb AD, Lawrentschuk N, Liodakis P, Moon D, Murphy DG, Peters JS, Ruljancich P, Verrill CL, Webb D, Wong LM, Zargar H, Costello AJ, Papenfuss AT, Hovens CM, Corcoran NM
Eur J Cancer 2021 May;148:440-450. Epub 2021 Mar 5 doi: 10.1016/j.ejca.2020.12.030. PMID: 33678516
Mucinous adenocarcinoma of prostate and prostatic adenocarcinoma with mucinous components: a clinicopathological analysis of 143 cases.
Samaratunga H, Delahunt B, Srigley JR, Yaxley J, Johannsen S, Coughlin G, Gianduzzo T, Kua B, Patterson I, Nacey JN, Egevad L
Histopathology 2017 Oct;71(4):641-647. Epub 2017 Jul 19 doi: 10.1111/his.13278. PMID: 28590015
The prognostic role of ERG immunopositivity in prostatic acinar adenocarcinoma: a study including 454 cases and review of the literature.
Xu B, Chevarie-Davis M, Chevalier S, Scarlata E, Zeizafoun N, Dragomir A, Tanguay S, Kassouf W, Aprikian A, Brimo F
Hum Pathol 2014 Mar;45(3):488-97. Epub 2013 Oct 23 doi: 10.1016/j.humpath.2013.10.012. PMID: 24406017
Neuroendocrine differentiation in human prostatic carcinoma.
di Sant'Agnese PA
Hum Pathol 1992 Mar;23(3):287-96. doi: 10.1016/0046-8177(92)90110-o. PMID: 1313390

Clinical prediction guides

Prostatic Ductal Adenocarcinoma Controlled for Tumor Grade, Stage, and Margin Status Does Not Independently Influence the Likelihood of Biochemical Recurrence in Localized Prostate Cancer After Radical Prostatectomy.
Kryvenko ON, Iakymenko OA, De Lima Guido LP, Bhattu AS, Merhe A, Mouzannar A, Briski LM, Oymagil I, Lugo I, Nemov I, Ritch CR, Kava BR, Punnen S, Jorda M, Parekh DJ, Gonzalgo ML
Arch Pathol Lab Med 2022 Aug 1;146(8):1012-1017. doi: 10.5858/arpa.2021-0048-OA. PMID: 34739539
High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate.
Zhou M
Mod Pathol 2018 Jan;31(S1):S71-79. doi: 10.1038/modpathol.2017.138. PMID: 29297491
Mucinous adenocarcinoma of prostate and prostatic adenocarcinoma with mucinous components: a clinicopathological analysis of 143 cases.
Samaratunga H, Delahunt B, Srigley JR, Yaxley J, Johannsen S, Coughlin G, Gianduzzo T, Kua B, Patterson I, Nacey JN, Egevad L
Histopathology 2017 Oct;71(4):641-647. Epub 2017 Jul 19 doi: 10.1111/his.13278. PMID: 28590015
Genetic profile of ductal adenocarcinoma of the prostate.
Seipel AH, Whitington T, Delahunt B, Samaratunga H, Mayrhofer M, Wiklund P, Grönberg H, Lindberg J, Egevad L
Hum Pathol 2017 Nov;69:1-7. Epub 2017 Apr 27 doi: 10.1016/j.humpath.2017.04.015. PMID: 28457729
The prognostic role of ERG immunopositivity in prostatic acinar adenocarcinoma: a study including 454 cases and review of the literature.
Xu B, Chevarie-Davis M, Chevalier S, Scarlata E, Zeizafoun N, Dragomir A, Tanguay S, Kassouf W, Aprikian A, Brimo F
Hum Pathol 2014 Mar;45(3):488-97. Epub 2013 Oct 23 doi: 10.1016/j.humpath.2013.10.012. PMID: 24406017

Recent systematic reviews

The Association of Invasive Cribriform Lesions With Adverse Prostatic Adenocarcinoma Outcomes: An Institutional Experience, Systematic Review, and Meta-analysis.
Luo X, Khurana JS, Jhala N, Zhao H, Wang H
Arch Pathol Lab Med 2019 Aug;143(8):1012-1021. Epub 2019 Feb 1 doi: 10.5858/arpa.2017-0582-RA. PMID: 30702333

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