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Locally Advanced Soft Tissue Sarcoma

MedGen UID:
1648947
Concept ID:
C4727772
Neoplastic Process

Definition

Soft tissue sarcoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Bhangu A, Broom L, Nepogodiev D, Gourevitch D, Desai A
Eur J Surg Oncol 2013 Apr;39(4):311-9. Epub 2013 Jan 23 doi: 10.1016/j.ejso.2012.12.018. PMID: 23351681
Hohenberger P, Wysocki WM
Oncologist 2008 Feb;13(2):175-86. doi: 10.1634/theoncologist.2007-0165. PMID: 18305063

Recent clinical studies

Etiology

Espenel S, Chargari C, Blanchard P, Bockel S, Morel D, Rivera S, Levy A, Deutsch E
Eur J Cancer 2022 Aug;171:242-258. Epub 2022 Jun 29 doi: 10.1016/j.ejca.2022.04.038. PMID: 35779346
Greto D, Saieva C, Loi M, Desideri I, Delli Paoli C, Lo Russo M, Pezzulla D, Teriaca MA, Lucidi S, Visani L, Terziani F, Olmetto E, Becherini C, Bonomo P, Francolini G, Campanacci DA, Scoccianti G, Livi L
Am J Clin Oncol 2019 Oct;42(10):749-754. doi: 10.1097/COC.0000000000000594. PMID: 31503061
Bonvalot S, Rimareix F, Causeret S, Le Péchoux C, Boulet B, Terrier P, Le Cesne A, Muret J
Ann Surg Oncol 2009 Dec;16(12):3350-7. Epub 2009 Oct 15 doi: 10.1245/s10434-009-0733-9. PMID: 19830495
Rossi CR, Mocellin S, Pilati P, Foletto M, Quintieri L, Palatini P, Lise M
Surg Oncol Clin N Am 2003 Jul;12(3):781-94. doi: 10.1016/s1055-3207(03)00030-9. PMID: 14567031
Eroglu A, Kocaoglu H, Demirci S, Akgül H
Eur J Surg Oncol 2000 Apr;26(3):213-21. doi: 10.1053/ejso.1999.0779. PMID: 10753532

Diagnosis

Bonvalot S, Wunder J, Gronchi A, Broto JM, Turcotte R, Rastrelli M, Papai Z, Radaelli S, Lindner LH, Shumelinsky F, Cubillo A, Rutkowski P, Demaire C, Strens D, Nalbantov G
Eur J Surg Oncol 2021 Aug;47(8):2166-2172. Epub 2021 Feb 26 doi: 10.1016/j.ejso.2021.02.024. PMID: 33676792
Villalobos VM, Mo G, Agulnik M, Pollack SM, Rushing DA, Singh A, Van Tine BA, McNaughton R, Decker RL, Zhang W, Shahir A, Cronier DM
Cancer Med 2020 Feb;9(3):882-893. Epub 2019 Dec 10 doi: 10.1002/cam4.2728. PMID: 31821732Free PMC Article
Greto D, Saieva C, Loi M, Desideri I, Delli Paoli C, Lo Russo M, Pezzulla D, Teriaca MA, Lucidi S, Visani L, Terziani F, Olmetto E, Becherini C, Bonomo P, Francolini G, Campanacci DA, Scoccianti G, Livi L
Am J Clin Oncol 2019 Oct;42(10):749-754. doi: 10.1097/COC.0000000000000594. PMID: 31503061
van Ginkel RJ, Kole AC, Nieweg OE, Molenaar WM, Pruim J, Koops HS, Vaalburg W, Hoekstra HJ
J Nucl Med 1999 Feb;40(2):262-7. PMID: 10025833
Olieman AF, van Ginkel RJ, Hoekstra HJ, Mooyaart EL, Molenaar WM, Koops HS
Ann Surg Oncol 1997 Jan;4(1):64-9. doi: 10.1007/BF02316812. PMID: 8985519

Therapy

Jakob J, Simeonova A, Kasper B, Ronellenfitsch U, Rauch G, Wenz F, Hohenberger P
Radiat Oncol 2016 Jun 3;11:77. doi: 10.1186/s13014-016-0654-2. PMID: 27255678Free PMC Article
Hoven-Gondrie ML, Bastiaannet E, van Ginkel RJ, Suurmeijer AJ, Hoekstra HJ
J Surg Oncol 2011 Jun 1;103(7):648-55. Epub 2011 Feb 17 doi: 10.1002/jso.21885. PMID: 21337343
Bonvalot S, Rimareix F, Causeret S, Le Péchoux C, Boulet B, Terrier P, Le Cesne A, Muret J
Ann Surg Oncol 2009 Dec;16(12):3350-7. Epub 2009 Oct 15 doi: 10.1245/s10434-009-0733-9. PMID: 19830495
Rossi CR, Mocellin S, Pilati P, Foletto M, Quintieri L, Palatini P, Lise M
Surg Oncol Clin N Am 2003 Jul;12(3):781-94. doi: 10.1016/s1055-3207(03)00030-9. PMID: 14567031
Eroglu A, Kocaoglu H, Demirci S, Akgül H
Eur J Surg Oncol 2000 Apr;26(3):213-21. doi: 10.1053/ejso.1999.0779. PMID: 10753532

Prognosis

Greto D, Saieva C, Loi M, Desideri I, Delli Paoli C, Lo Russo M, Pezzulla D, Teriaca MA, Lucidi S, Visani L, Terziani F, Olmetto E, Becherini C, Bonomo P, Francolini G, Campanacci DA, Scoccianti G, Livi L
Am J Clin Oncol 2019 Oct;42(10):749-754. doi: 10.1097/COC.0000000000000594. PMID: 31503061
Hoven-Gondrie ML, Bastiaannet E, van Ginkel RJ, Suurmeijer AJ, Hoekstra HJ
J Surg Oncol 2011 Jun 1;103(7):648-55. Epub 2011 Feb 17 doi: 10.1002/jso.21885. PMID: 21337343
Bonvalot S, Rimareix F, Causeret S, Le Péchoux C, Boulet B, Terrier P, Le Cesne A, Muret J
Ann Surg Oncol 2009 Dec;16(12):3350-7. Epub 2009 Oct 15 doi: 10.1245/s10434-009-0733-9. PMID: 19830495
Rossi CR, Mocellin S, Pilati P, Foletto M, Quintieri L, Palatini P, Lise M
Surg Oncol Clin N Am 2003 Jul;12(3):781-94. doi: 10.1016/s1055-3207(03)00030-9. PMID: 14567031
Eroglu A, Kocaoglu H, Demirci S, Akgül H
Eur J Surg Oncol 2000 Apr;26(3):213-21. doi: 10.1053/ejso.1999.0779. PMID: 10753532

Clinical prediction guides

Bonvalot S, Rutkowski PL, Thariat J, Carrère S, Ducassou A, Sunyach MP, Agoston P, Hong AM, Mervoyer A, Rastrelli M, Moreno V, Li RK, Tiangco BJ, Herráez AC, Gronchi A, Sy-Ortin T, Hohenberger P, de Baère T, Cesne AL, Helfre S, Saada-Bouzid E, Anghel RM, Kantor G, Montero A, Loong HH, Vergés R, Kacso G, Austen L, Servois VF, Wardelmann E, Dimitriu M, Said P, Lazar AJ, Bovée JVMG, Péchoux CL, Pápai Z
Int J Radiat Oncol Biol Phys 2022 Nov 1;114(3):422-432. Epub 2022 Jul 16 doi: 10.1016/j.ijrobp.2022.07.001. PMID: 35850363
Monga V, Miller BJ, Tanas M, Boukhar S, Allen B, Anderson C, Stephens L, Hartwig S, Varga S, Houtman J, Wang L, Zhang W, Jaber O, Thomason J, Kuehn D, Rajput M, Metz C, Zamba KD, Mott S, Abanonu C, Bhatia S, Milhem M
J Immunother Cancer 2021 Jul;9(7) doi: 10.1136/jitc-2021-003119. PMID: 34330766Free PMC Article
Greto D, Loi M, Saieva C, Muntoni C, Delli Paoli C, Becherini C, Ciabatti C, Perna M, Campanacci D, Terziani F, Beltrami G, Scoccianti G, Bonomo P, Meattini I, Desideri I, Simontacchi G, Mangoni M, Livi L
Tumori 2018 Oct;104(5):322-329. Epub 2018 Apr 11 doi: 10.1177/0300891618765565. PMID: 29714662
Bonvalot S, Rimareix F, Causeret S, Le Péchoux C, Boulet B, Terrier P, Le Cesne A, Muret J
Ann Surg Oncol 2009 Dec;16(12):3350-7. Epub 2009 Oct 15 doi: 10.1245/s10434-009-0733-9. PMID: 19830495
Rossi CR, Mocellin S, Pilati P, Foletto M, Quintieri L, Palatini P, Lise M
Surg Oncol Clin N Am 2003 Jul;12(3):781-94. doi: 10.1016/s1055-3207(03)00030-9. PMID: 14567031

Recent systematic reviews

Bhangu A, Broom L, Nepogodiev D, Gourevitch D, Desai A
Eur J Surg Oncol 2013 Apr;39(4):311-9. Epub 2013 Jan 23 doi: 10.1016/j.ejso.2012.12.018. PMID: 23351681

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