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Metastatic Colon Carcinoma

MedGen UID:
1649079
•Concept ID:
C4744565
•
Neoplastic Process

Definition

A carcinoma that arises from the colon and has metastasized to another anatomic site. [from NCI]

Professional guidelines

PubMed

The clinical utility of the Das-1 monoclonal antibody in identifying adenocarcinoma of the colon metastatic to the liver in fine-needle aspiration tissue.
Zimmerman RL, Das KM, Burke MA, Young NA, Solomides CC, Bibbo M
Cancer 2002 Dec 25;96(6):370-3. doi: 10.1002/cncr.10882. PMID: 12478685
The hemodynamic effects of treatment with interleukin-2 and lymphokine-activated killer cells.
Gaynor ER, Vitek L, Sticklin L, Creekmore SP, Ferraro ME, Thomas JX Jr, Fisher SG, Fisher RI
Ann Intern Med 1988 Dec 15;109(12):953-8. doi: 10.7326/0003-4819-109-12-953. PMID: 3264128
Intra-arterial chemotherapy using an implantable infusion pump and liver irradiation for the treatment of hepatic metastases.
Barone RM, Byfield JE, Goldfarb PB, Frankel S, Ginn C, Greer S
Cancer 1982 Sep 1;50(5):850-62. doi: 10.1002/1097-0142(19820901)50:5<850::aid-cncr2820500508>3.0.co;2-2. PMID: 6212114

Recent clinical studies

Etiology

Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Romagnoli R, Preti D, Hamel E, Bortolozzi R, Viola G, Brancale A, Ferla S, Morciano G, Pinton P
Bioorg Chem 2021 Jul;112:104919. Epub 2021 Apr 20 doi: 10.1016/j.bioorg.2021.104919. PMID: 33957538
Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis.
Lamy V, Roussi S, Chaabi M, Gossé F, Schall N, Lobstein A, Raul F
Carcinogenesis 2007 Jul;28(7):1575-81. Epub 2007 Apr 13 doi: 10.1093/carcin/bgm080. PMID: 17434926
Expression of cytokeratin 20 in the blood of patients with disseminated carcinoma of the pancreas, colon, stomach, and lung.
Chausovsky G, Luchansky M, Figer A, Shapira J, Gottfried M, Novis B, Bogelman G, Zemer R, Zimlichman S, Klein A
Cancer 1999 Dec 1;86(11):2398-405. PMID: 10590383
Ultrasound-guided hepatic cryosurgery in the treatment of metastatic colon carcinoma. Preliminary results.
Onik G, Rubinsky B, Zemel R, Weaver L, Diamond D, Cobb C, Porterfield B
Cancer 1991 Feb 15;67(4):901-7. doi: 10.1002/1097-0142(19910215)67:4<901::aid-cncr2820670408>3.0.co;2-z. PMID: 1991262
Phase II trial of high-dose melphalan and autologous bone marrow transplantation for metastatic colon carcinoma.
Leff RS, Thompson JM, Johnson DB, Mosley KR, Daly MB, Knight WA 3rd, Ruxer RL Jr, Messerschmidt GL
J Clin Oncol 1986 Nov;4(11):1586-91. doi: 10.1200/JCO.1986.4.11.1586. PMID: 3534154

Diagnosis

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth.
Lu C, Klement JD, Yang D, Albers T, Lebedyeva IO, Waller JL, Liu K
Cancer Lett 2020 Apr 28;476:87-96. Epub 2020 Feb 12 doi: 10.1016/j.canlet.2020.02.004. PMID: 32061753Free PMC Article
Bilateral Internal Auditory Canal Metastasis of Colon Carcinoma Mimicking Neurofibromatosis Type II: A Case Report and Literature Review.
Zhang S, Zhao H, Sa R, Qin X, Qu L, Wang Y, Deng S, Yu H, Xu S
World Neurosurg 2019 Jul;127:381-386. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.02.166. PMID: 30862585
Circulating and imaging markers for angiogenesis.
Pathak AP, Hochfeld WE, Goodman SL, Pepper MS
Angiogenesis 2008;11(4):321-35. Epub 2008 Oct 17 doi: 10.1007/s10456-008-9119-z. PMID: 18925424
Differential role of Fas/Fas ligand interactions in cytolysis of primary and metastatic colon carcinoma cell lines by human antigen-specific CD8+ CTL.
Bergmann-Leitner ES, Abrams SI
J Immunol 2000 May 1;164(9):4941-54. doi: 10.4049/jimmunol.164.9.4941. PMID: 10779805
Colon carcinoma metastatic to the lung. Cytologic manifestations and distinction from primary pulmonary adenocarcinoma.
Flint A, Lloyd RV
Acta Cytol 1992 Mar-Apr;36(2):230-5. PMID: 1543007

Therapy

Increased glucocorticoid receptor activity and proliferation in metastatic colon cancer.
Tian D, Tian M, Han G, Li JL
Sci Rep 2019 Aug 2;9(1):11257. doi: 10.1038/s41598-019-47696-2. PMID: 31375708Free PMC Article
Heterogeneity-related anticancer therapy response differences in metastatic colon carcinoma: new hints to tumor-site-based personalized cancer therapy.
Pan W, Huang S, Zhang J, Zhao B, Wang H, Liu F, Jin K, Mou X
Hepatogastroenterology 2013 Nov-Dec;60(128):1927-34. PMID: 24719929
Cell fusion promotes chemoresistance in metastatic colon carcinoma.
Carloni V, Mazzocca A, Mello T, Galli A, Capaccioli S
Oncogene 2013 May 23;32(21):2649-60. Epub 2012 Jul 2 doi: 10.1038/onc.2012.268. PMID: 22751128
Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism.
Cambien B, Karimdjee BF, Richard-Fiardo P, Bziouech H, Barthel R, Millet MA, Martini V, Birnbaum D, Scoazec JY, Abello J, Al Saati T, Johnson MG, Sullivan TJ, Medina JC, Collins TL, Schmid-Alliana A, Schmid-Antomarchi H
Br J Cancer 2009 Jun 2;100(11):1755-64. Epub 2009 May 12 doi: 10.1038/sj.bjc.6605078. PMID: 19436305Free PMC Article
Phase II trial of high-dose melphalan and autologous bone marrow transplantation for metastatic colon carcinoma.
Leff RS, Thompson JM, Johnson DB, Mosley KR, Daly MB, Knight WA 3rd, Ruxer RL Jr, Messerschmidt GL
J Clin Oncol 1986 Nov;4(11):1586-91. doi: 10.1200/JCO.1986.4.11.1586. PMID: 3534154

Prognosis

Bilateral Internal Auditory Canal Metastasis of Colon Carcinoma Mimicking Neurofibromatosis Type II: A Case Report and Literature Review.
Zhang S, Zhao H, Sa R, Qin X, Qu L, Wang Y, Deng S, Yu H, Xu S
World Neurosurg 2019 Jul;127:381-386. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.02.166. PMID: 30862585
Chemotherapy in patient with colon cancer after renal transplantation: A case report with literature review.
Fang W
Medicine (Baltimore) 2018 Feb;97(5):e9678. doi: 10.1097/MD.0000000000009678. PMID: 29384845Free PMC Article
Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism.
Cambien B, Karimdjee BF, Richard-Fiardo P, Bziouech H, Barthel R, Millet MA, Martini V, Birnbaum D, Scoazec JY, Abello J, Al Saati T, Johnson MG, Sullivan TJ, Medina JC, Collins TL, Schmid-Alliana A, Schmid-Antomarchi H
Br J Cancer 2009 Jun 2;100(11):1755-64. Epub 2009 May 12 doi: 10.1038/sj.bjc.6605078. PMID: 19436305Free PMC Article
Cavernous sinus syndrome caused by metastatic colon carcinoma.
Oneç B, Oksüzoğlu B, Hatipoğlu HG, Oneç K, Azak A, Zengin N
Clin Colorectal Cancer 2007 Jul;6(8):593-6. doi: 10.3816/CCC.2007.n.028. PMID: 17681107
Ultrasound-guided hepatic cryosurgery in the treatment of metastatic colon carcinoma. Preliminary results.
Onik G, Rubinsky B, Zemel R, Weaver L, Diamond D, Cobb C, Porterfield B
Cancer 1991 Feb 15;67(4):901-7. doi: 10.1002/1097-0142(19910215)67:4<901::aid-cncr2820670408>3.0.co;2-z. PMID: 1991262

Clinical prediction guides

Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Romagnoli R, Preti D, Hamel E, Bortolozzi R, Viola G, Brancale A, Ferla S, Morciano G, Pinton P
Bioorg Chem 2021 Jul;112:104919. Epub 2021 Apr 20 doi: 10.1016/j.bioorg.2021.104919. PMID: 33957538
Identification, characterization and utilization of tumor cell selectin ligands in the design of colon cancer diagnostics.
Thomas SN, Tong Z, Stebe KJ, Konstantopoulos K
Biorheology 2009;46(3):207-25. doi: 10.3233/BIR-2009-0534. PMID: 19581728
Constitutive expression of growth regulated oncogene (gro) in human colon carcinoma cells with different metastatic potential and its role in regulating their metastatic phenotype.
Li A, Varney ML, Singh RK
Clin Exp Metastasis 2004;21(7):571-9. doi: 10.1007/s10585-004-5458-3. PMID: 15787094
Differential role of Fas/Fas ligand interactions in cytolysis of primary and metastatic colon carcinoma cell lines by human antigen-specific CD8+ CTL.
Bergmann-Leitner ES, Abrams SI
J Immunol 2000 May 1;164(9):4941-54. doi: 10.4049/jimmunol.164.9.4941. PMID: 10779805
Phase II trial of high-dose melphalan and autologous bone marrow transplantation for metastatic colon carcinoma.
Leff RS, Thompson JM, Johnson DB, Mosley KR, Daly MB, Knight WA 3rd, Ruxer RL Jr, Messerschmidt GL
J Clin Oncol 1986 Nov;4(11):1586-91. doi: 10.1200/JCO.1986.4.11.1586. PMID: 3534154

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