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Metastatic Uveal Melanoma

MedGen UID:
1649122
Concept ID:
C4725091
Neoplastic Process

Definition

Uveal melanoma that has spread from its primary site to another anatomic site. [from NCI]

Professional guidelines

PubMed

Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S
Nat Rev Clin Oncol 2023 Feb;20(2):99-115. Epub 2023 Jan 4 doi: 10.1038/s41571-022-00714-1. PMID: 36600005
Chen LN, Carvajal RD
Expert Rev Anticancer Ther 2022 Oct;22(10):1017-1027. Epub 2022 Sep 19 doi: 10.1080/14737140.2022.2124971. PMID: 36102132Free PMC Article
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article

Recent clinical studies

Etiology

Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S
Nat Rev Clin Oncol 2023 Feb;20(2):99-115. Epub 2023 Jan 4 doi: 10.1038/s41571-022-00714-1. PMID: 36600005
Reichstein D, Brock A, Lietman C, McKean M
Curr Opin Ophthalmol 2022 Nov 1;33(6):585-590. Epub 2022 Sep 8 doi: 10.1097/ICU.0000000000000905. PMID: 36094043
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Nathan P, Hassel JC, Rutkowski P, Baurain JF, Butler MO, Schlaak M, Sullivan RJ, Ochsenreither S, Dummer R, Kirkwood JM, Joshua AM, Sacco JJ, Shoushtari AN, Orloff M, Piulats JM, Milhem M, Salama AKS, Curti B, Demidov L, Gastaud L, Mauch C, Yushak M, Carvajal RD, Hamid O, Abdullah SE, Holland C, Goodall H, Piperno-Neumann S; IMCgp100-202 Investigators
N Engl J Med 2021 Sep 23;385(13):1196-1206. doi: 10.1056/NEJMoa2103485. PMID: 34551229
Park JJ, Diefenbach RJ, Joshua AM, Kefford RF, Carlino MS, Rizos H
Pigment Cell Melanoma Res 2018 Nov;31(6):661-672. Epub 2018 May 23 doi: 10.1111/pcmr.12708. PMID: 29738114

Diagnosis

Trivedi DB, Aldulaimi N, Karydis I, Wheater M, Modi S, Stedman B, Karavias D, Primrose J, Pearce N, Takhar AS
Melanoma Res 2023 Feb 1;33(1):71-79. Epub 2022 Nov 21 doi: 10.1097/CMR.0000000000000867. PMID: 36409208
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Garg G, Kivelä TT, Finger PT
Indian J Ophthalmol 2022 Jan;70(1):271-274. doi: 10.4103/ijo.IJO_1478_21. PMID: 34937253Free PMC Article
Kivelä T, Eskelin S, Kujala E
Int Ophthalmol Clin 2006 Winter;46(1):133-49. doi: 10.1097/01.iio.0000195861.71558.13. PMID: 16365560
Singh AD, Borden EC
Ophthalmol Clin North Am 2005 Mar;18(1):143-50, ix. doi: 10.1016/j.ohc.2004.07.003. PMID: 15763199

Therapy

van de Donk NWCJ, Zweegman S
Lancet 2023 Jul 8;402(10396):142-158. Epub 2023 Jun 1 doi: 10.1016/S0140-6736(23)00521-4. PMID: 37271153
Dhillon S
Drugs 2022 Apr;82(6):703-710. doi: 10.1007/s40265-022-01704-4. PMID: 35364798
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Nathan P, Hassel JC, Rutkowski P, Baurain JF, Butler MO, Schlaak M, Sullivan RJ, Ochsenreither S, Dummer R, Kirkwood JM, Joshua AM, Sacco JJ, Shoushtari AN, Orloff M, Piulats JM, Milhem M, Salama AKS, Curti B, Demidov L, Gastaud L, Mauch C, Yushak M, Carvajal RD, Hamid O, Abdullah SE, Holland C, Goodall H, Piperno-Neumann S; IMCgp100-202 Investigators
N Engl J Med 2021 Sep 23;385(13):1196-1206. doi: 10.1056/NEJMoa2103485. PMID: 34551229
Pelster MS, Gruschkus SK, Bassett R, Gombos DS, Shephard M, Posada L, Glover MS, Simien R, Diab A, Hwu P, Carter BW, Patel SP
J Clin Oncol 2021 Feb 20;39(6):599-607. Epub 2020 Oct 30 doi: 10.1200/JCO.20.00605. PMID: 33125309Free PMC Article

Prognosis

Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S
Nat Rev Clin Oncol 2023 Feb;20(2):99-115. Epub 2023 Jan 4 doi: 10.1038/s41571-022-00714-1. PMID: 36600005
Chen LN, Carvajal RD
Expert Rev Anticancer Ther 2022 Oct;22(10):1017-1027. Epub 2022 Sep 19 doi: 10.1080/14737140.2022.2124971. PMID: 36102132Free PMC Article
Reichstein D, Brock A, Lietman C, McKean M
Curr Opin Ophthalmol 2022 Nov 1;33(6):585-590. Epub 2022 Sep 8 doi: 10.1097/ICU.0000000000000905. PMID: 36094043
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article

Clinical prediction guides

Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Koch EAT, Petzold A, Wessely A, Dippel E, Erdmann M, Heinzerling L, Hohberger B, Knorr H, Leiter U, Meier F, Mohr P, Rahimi F, Schell B, Schlaak M, Terheyden P, Schuler-Thurner B, Ugurel S, Utikal J, Vera J, Weichenthal M, Ziller F, Berking C, Heppt MV
Cancer Immunol Immunother 2022 Jun;71(6):1467-1477. Epub 2021 Oct 28 doi: 10.1007/s00262-021-03090-4. PMID: 34709438Free PMC Article
Middleton MR, McAlpine C, Woodcock VK, Corrie P, Infante JR, Steven NM, Evans TRJ, Anthoney A, Shoushtari AN, Hamid O, Gupta A, Vardeu A, Leach E, Naidoo R, Stanhope S, Lewis S, Hurst J, O'Kelly I, Sznol M
Clin Cancer Res 2020 Nov 15;26(22):5869-5878. Epub 2020 Aug 18 doi: 10.1158/1078-0432.CCR-20-1247. PMID: 32816891Free PMC Article
Lorenzo D, Piulats JM, Ochoa M, Arias L, Gutiérrez C, Català J, Cobos E, Garcia-Bru P, Dias B, Padrón-Pérez N, Caminal JM
Jpn J Ophthalmol 2019 Mar;63(2):197-209. Epub 2019 Feb 22 doi: 10.1007/s10384-019-00656-9. PMID: 30796549
Buder K, Gesierich A, Gelbrich G, Goebeler M
Cancer Med 2013 Oct;2(5):674-86. Epub 2013 Sep 18 doi: 10.1002/cam4.133. PMID: 24403233Free PMC Article

Recent systematic reviews

Pham JP, On L, Ardolino L, Hurwitz J, Salaun H, Sim HW, Joshua AM
Melanoma Res 2023 Aug 1;33(4):316-325. Epub 2023 May 18 doi: 10.1097/CMR.0000000000000900. PMID: 37199712
Comito F, Marchese PV, Ricci AD, Tober N, Peterle C, Sperandi F, Melotti B
Future Oncol 2021 Nov;17(33):4583-4606. Epub 2021 Aug 25 doi: 10.2217/fon-2021-0318. PMID: 34431316
Zhang HG, Moser JC, Dalvin LA
Acta Oncol 2020 Nov;59(11):1401-1408. Epub 2020 Jul 1 doi: 10.1080/0284186X.2020.1787508. PMID: 32609032
Rantala ES, Hernberg M, Kivelä TT
Melanoma Res 2019 Dec;29(6):561-568. doi: 10.1097/CMR.0000000000000575. PMID: 30664106Free PMC Article
Heppt MV, Steeb T, Schlager JG, Rosumeck S, Dressler C, Ruzicka T, Nast A, Berking C
Cancer Treat Rev 2017 Nov;60:44-52. Epub 2017 Aug 24 doi: 10.1016/j.ctrv.2017.08.009. PMID: 28881222

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