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Advanced Oral Cavity Squamous Cell Carcinoma

MedGen UID:
1650313
Concept ID:
C4727683
Neoplastic Process
Synonym: Advanced Squamous Cell Carcinoma of the Oral Cavity

Definition

A squamous cell carcinoma of the oral cavity that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Oral Cavity Squamous Cell Carcinoma

Professional guidelines

PubMed

Asarkar AA, Chang BA, de Bree R, Kowalski LP, Guntinas-Lichius O, Bradley PJ, de Graaf P, Strojan P, Rao KN, Mäkitie AA, López F, Rinaldo A, Palme C, Genden EM, Sanabria A, Rodrigo JP, Ferlito A
Adv Ther 2024 Jun;41(6):2133-2150. Epub 2024 Apr 20 doi: 10.1007/s12325-024-02861-6. PMID: 38642199
Tang AL, O'Neil T, McDermott S, Tripathi S, Tikhtman R, Mark JR, Patil Y, Tabangin M, Altaye M, Wise-Draper TM, Zender CA
JAMA Otolaryngol Head Neck Surg 2022 Oct 1;148(10):935-939. doi: 10.1001/jamaoto.2022.2291. PMID: 36006622Free PMC Article
Tangthongkum M, Kirtsreesakul V, Supanimitjaroenporn P, Leelasawatsuk P
Eur Arch Otorhinolaryngol 2017 Jun;274(6):2567-2572. Epub 2017 Mar 20 doi: 10.1007/s00405-017-4540-9. PMID: 28321535

Recent clinical studies

Etiology

Diebolt JH, Yu KM, Wood S, Ziegler A, France A, Villwock MR, Alvi SA, Kakarala K, Shnayder Y, Gan GN, Lominska CE, Neupane P, Bur AM
Otolaryngol Head Neck Surg 2023 Jul;169(1):69-75. Epub 2023 Jan 28 doi: 10.1177/01945998221116746. PMID: 35917167Free PMC Article
Tang AL, O'Neil T, McDermott S, Tripathi S, Tikhtman R, Mark JR, Patil Y, Tabangin M, Altaye M, Wise-Draper TM, Zender CA
JAMA Otolaryngol Head Neck Surg 2022 Oct 1;148(10):935-939. doi: 10.1001/jamaoto.2022.2291. PMID: 36006622Free PMC Article
Shen P, Qiao B, Jin N, Wang S
Invest New Drugs 2022 Dec;40(6):1282-1289. Epub 2022 Aug 16 doi: 10.1007/s10637-022-01293-9. PMID: 35972629
Sambasivan K, Sassoon I, Thavaraj S, Kennedy R, Doss G, Michaelidou A, Odell E, Sandison A, Hall G, Morgan P, Collins LHC, Lyons A, Cascarini L, Fry A, Oakley R, Simo R, Jeannon JP, Petkar I, Reis Ferreira M, Kong A, Lei M, Guerrero Urbano T
Radiother Oncol 2021 Jul;160:54-60. Epub 2021 May 3 doi: 10.1016/j.radonc.2021.04.003. PMID: 33845044
De Paz D, Kao HK, Huang Y, Chang KP
Curr Oncol Rep 2017 Aug 10;19(10):65. doi: 10.1007/s11912-017-0624-3. PMID: 28799122

Diagnosis

Lu HJ, Tseng SW, Peng CY, Tseng HC, Hsin CH, Chen HL, Huang WS, Wu MF, Yang MH, Chang PM
Postgrad Med 2021 Apr;133(3):377-384. Epub 2020 Sep 11 doi: 10.1080/00325481.2020.1809869. PMID: 32791023
Mascarella MA, Azzi JL, da Silva SD, Mlynarek A, Forest VI, Hier M, Richardson K, Sadeghi N
Head Neck 2019 Oct;41(10):3624-3630. Epub 2019 Aug 5 doi: 10.1002/hed.25885. PMID: 31385387
De Paz D, Kao HK, Huang Y, Chang KP
Curr Oncol Rep 2017 Aug 10;19(10):65. doi: 10.1007/s11912-017-0624-3. PMID: 28799122
Huang CG, Lee LA, Tsao KC, Liao CT, Yang LY, Kang CJ, Chang KP, Huang SF, Chen IH, Yang SL, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC
J Clin Virol 2014 Oct;61(2):230-6. Epub 2014 Jul 22 doi: 10.1016/j.jcv.2014.07.007. PMID: 25097016
Zhang H, Dziegielewski PT, Biron VL, Szudek J, Al-Qahatani KH, O'Connell DA, Harris JR, Seikaly H
J Otolaryngol Head Neck Surg 2013 Apr 19;42(1):30. doi: 10.1186/1916-0216-42-30. PMID: 23672952Free PMC Article

Therapy

Tang AL, O'Neil T, McDermott S, Tripathi S, Tikhtman R, Mark JR, Patil Y, Tabangin M, Altaye M, Wise-Draper TM, Zender CA
JAMA Otolaryngol Head Neck Surg 2022 Oct 1;148(10):935-939. doi: 10.1001/jamaoto.2022.2291. PMID: 36006622Free PMC Article
Shen P, Qiao B, Jin N, Wang S
Invest New Drugs 2022 Dec;40(6):1282-1289. Epub 2022 Aug 16 doi: 10.1007/s10637-022-01293-9. PMID: 35972629
Abdelmeguid AS, Silver NL, Boonsripitayanon M, Glisson BS, Ferrarotto R, Gunn GB, Phan J, Gillenwater AM, Hanna EY
Cancer 2021 Sep 1;127(17):3107-3112. Epub 2021 Apr 28 doi: 10.1002/cncr.33616. PMID: 33909292
Lu HJ, Tseng SW, Peng CY, Tseng HC, Hsin CH, Chen HL, Huang WS, Wu MF, Yang MH, Chang PM
Postgrad Med 2021 Apr;133(3):377-384. Epub 2020 Sep 11 doi: 10.1080/00325481.2020.1809869. PMID: 32791023
Mascarella MA, Azzi JL, da Silva SD, Mlynarek A, Forest VI, Hier M, Richardson K, Sadeghi N
Head Neck 2019 Oct;41(10):3624-3630. Epub 2019 Aug 5 doi: 10.1002/hed.25885. PMID: 31385387

Prognosis

Diebolt JH, Yu KM, Wood S, Ziegler A, France A, Villwock MR, Alvi SA, Kakarala K, Shnayder Y, Gan GN, Lominska CE, Neupane P, Bur AM
Otolaryngol Head Neck Surg 2023 Jul;169(1):69-75. Epub 2023 Jan 28 doi: 10.1177/01945998221116746. PMID: 35917167Free PMC Article
Sambasivan K, Sassoon I, Thavaraj S, Kennedy R, Doss G, Michaelidou A, Odell E, Sandison A, Hall G, Morgan P, Collins LHC, Lyons A, Cascarini L, Fry A, Oakley R, Simo R, Jeannon JP, Petkar I, Reis Ferreira M, Kong A, Lei M, Guerrero Urbano T
Radiother Oncol 2021 Jul;160:54-60. Epub 2021 May 3 doi: 10.1016/j.radonc.2021.04.003. PMID: 33845044
Lu HJ, Tseng SW, Peng CY, Tseng HC, Hsin CH, Chen HL, Huang WS, Wu MF, Yang MH, Chang PM
Postgrad Med 2021 Apr;133(3):377-384. Epub 2020 Sep 11 doi: 10.1080/00325481.2020.1809869. PMID: 32791023
De Paz D, Kao HK, Huang Y, Chang KP
Curr Oncol Rep 2017 Aug 10;19(10):65. doi: 10.1007/s11912-017-0624-3. PMID: 28799122
Chiou SJ, Chen CH
Med Sci Monit Basic Res 2013 Oct 21;19:271-3. doi: 10.12659/MSMBR.889457. PMID: 24146000Free PMC Article

Clinical prediction guides

Diebolt JH, Yu KM, Wood S, Ziegler A, France A, Villwock MR, Alvi SA, Kakarala K, Shnayder Y, Gan GN, Lominska CE, Neupane P, Bur AM
Otolaryngol Head Neck Surg 2023 Jul;169(1):69-75. Epub 2023 Jan 28 doi: 10.1177/01945998221116746. PMID: 35917167Free PMC Article
Abdelmeguid AS, Silver NL, Boonsripitayanon M, Glisson BS, Ferrarotto R, Gunn GB, Phan J, Gillenwater AM, Hanna EY
Cancer 2021 Sep 1;127(17):3107-3112. Epub 2021 Apr 28 doi: 10.1002/cncr.33616. PMID: 33909292
Sambasivan K, Sassoon I, Thavaraj S, Kennedy R, Doss G, Michaelidou A, Odell E, Sandison A, Hall G, Morgan P, Collins LHC, Lyons A, Cascarini L, Fry A, Oakley R, Simo R, Jeannon JP, Petkar I, Reis Ferreira M, Kong A, Lei M, Guerrero Urbano T
Radiother Oncol 2021 Jul;160:54-60. Epub 2021 May 3 doi: 10.1016/j.radonc.2021.04.003. PMID: 33845044
Lu HJ, Tseng SW, Peng CY, Tseng HC, Hsin CH, Chen HL, Huang WS, Wu MF, Yang MH, Chang PM
Postgrad Med 2021 Apr;133(3):377-384. Epub 2020 Sep 11 doi: 10.1080/00325481.2020.1809869. PMID: 32791023
Mascarella MA, Azzi JL, da Silva SD, Mlynarek A, Forest VI, Hier M, Richardson K, Sadeghi N
Head Neck 2019 Oct;41(10):3624-3630. Epub 2019 Aug 5 doi: 10.1002/hed.25885. PMID: 31385387

Recent systematic reviews

Membreno PV, Luttrell JB, Mamidala MP, Schwartz DL, Hayes DN, Gleysteen JP, Gillespie MB
Head Neck 2021 Oct;43(10):3165-3176. Epub 2021 Jun 24 doi: 10.1002/hed.26779. PMID: 34165221

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