U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Metastatic Urethral Carcinoma

MedGen UID:
1654675
•Concept ID:
C4727596
•
Neoplastic Process
Synonyms: Metastatic Carcinoma of the Urethra; Metastatic Carcinoma of Urethra

Definition

Urethral carcinoma that has spread to another anatomical site. [from NCI]

Professional guidelines

PubMed

An assessment of urethral radiation exposure in the treatment of endometrial and rectal cancers.
Hines K, Nieto K, Dezarn W, Greven K, Krol B, Matthews C, Parker-Autry C
Int Urogynecol J 2023 Apr;34(4):929-935. Epub 2022 Oct 1 doi: 10.1007/s00192-022-05363-7. PMID: 36181547
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479

Recent clinical studies

Etiology

Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2022 Nov;129:71-80. Epub 2022 Aug 28 doi: 10.1016/j.humpath.2022.08.003. PMID: 36037997
Radiotherapy in Metastatic Urothelial Carcinoma: Rationale and Clinical Applications.
Vassiliou V, Katsila T, Sodergren SC, Kardamakis D
Anticancer Res 2022 Aug;42(8):3767-3778. doi: 10.21873/anticanres.15867. PMID: 35896266
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Diagnosis

Radiotherapy in Metastatic Urothelial Carcinoma: Rationale and Clinical Applications.
Vassiliou V, Katsila T, Sodergren SC, Kardamakis D
Anticancer Res 2022 Aug;42(8):3767-3778. doi: 10.21873/anticanres.15867. PMID: 35896266
Follow-up Management of Cystectomy Patients.
Reddy M, Kader K
Urol Clin North Am 2018 May;45(2):241-247. doi: 10.1016/j.ucl.2018.01.001. PMID: 29650139
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Prepubertal vulvovaginopathies.
Pokorny SF
Obstet Gynecol Clin North Am 1992 Mar;19(1):39-58. PMID: 1584544
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Therapy

Granular cell tumors of the urethra.
Evmorfopoulos K, Tzortzis V, Vlachostergios PJ
Cancer Treat Res Commun 2023;35:100695. Epub 2023 Mar 17 doi: 10.1016/j.ctarc.2023.100695. PMID: 36940531
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
Chemotherapy for penile and urethral carcinoma.
Trabulsi EJ, Hoffman-Censits J
Urol Clin North Am 2010 Aug;37(3):467-74. doi: 10.1016/j.ucl.2010.04.010. PMID: 20674701
Superficial bladder cancer therapy.
Schenkman E, Lamm DL
ScientificWorldJournal 2004 Jun 28;4 Suppl 1:387-99. doi: 10.1100/tsw.2004.81. PMID: 15349563Free PMC Article

Prognosis

Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2022 Nov;129:71-80. Epub 2022 Aug 28 doi: 10.1016/j.humpath.2022.08.003. PMID: 36037997
Radiotherapy in Metastatic Urothelial Carcinoma: Rationale and Clinical Applications.
Vassiliou V, Katsila T, Sodergren SC, Kardamakis D
Anticancer Res 2022 Aug;42(8):3767-3778. doi: 10.21873/anticanres.15867. PMID: 35896266
Mucinous and secondary tumors of the prostate.
Osunkoya AO
Mod Pathol 2018 Jan;31(S1):S80-S95. doi: 10.1038/modpathol.2017.132. PMID: 29297488
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Clinical prediction guides

Risk factors for bladder neck contracture after transurethral resection of the prostate.
Goßler C, Pfänder F, Haas M, Mayr R, Gierth M, Burger M, Rosenhammer B, Breyer J
Prostate 2023 Aug;83(11):1020-1027. Epub 2023 Apr 23 doi: 10.1002/pros.24543. PMID: 37089004
Primary tumor surgery improves survival in non-metastatic primary urethral carcinoma patients: a large population-based investigation.
Wu J, Wang YC, Luo WJ, Bo-Dai, Ye DW, Zhu YP
BMC Cancer 2021 Jul 27;21(1):857. doi: 10.1186/s12885-021-08603-z. PMID: 34315433Free PMC Article
Comprehensive genomic profiling of histologic subtypes of urethral carcinomas.
Jacob J, Necchi A, Grivas P, Hughes M, Sanford T, Mollapour M, Shapiro O, Talal A, Sokol E, Vergilio JA, Killian J, Lin D, Williams E, Tse J, Ramkissoon S, Severson E, Hemmerich A, Ferguson N, Edgerly C, Duncan D, Huang R, Chung J, Madison R, Alexander B, Venstrom J, Reddy P, McGregor K, Elvin J, Schrock A, Danziger N, Pavlick D, Ross J, Bratslavsky G
Urol Oncol 2021 Oct;39(10):731.e1-731.e15. Epub 2021 Jun 30 doi: 10.1016/j.urolonc.2020.12.021. PMID: 34215504
A systematic review and meta-analysis on complications of transanal total mesorectal excision.
An Y, Roodbeen SX, Talboom K, Tanis PJ, Bemelman WA, Hompes R
Colorectal Dis 2021 Oct;23(10):2527-2538. Epub 2021 Jul 11 doi: 10.1111/codi.15792. PMID: 34174138
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479

Recent systematic reviews

Patient- and Tumour-related Prognostic Factors for Urinary Incontinence After Radical Prostatectomy for Nonmetastatic Prostate Cancer: A Systematic Review and Meta-analysis.
Lardas M, Grivas N, Debray TPA, Zattoni F, Berridge C, Cumberbatch M, Van den Broeck T, Briers E, De Santis M, Farolfi A, Fossati N, Gandaglia G, Gillessen S, O'Hanlon S, Henry A, Liew M, Mason M, Moris L, Oprea-Lager D, Ploussard G, Rouviere O, Schoots IG, van der Kwast T, van der Poel H, Wiegel T, Willemse PP, Yuan CY, Grummet JP, Tilki D, van den Bergh RCN, Lam TB, Cornford P, Mottet N
Eur Urol Focus 2022 May;8(3):674-689. Epub 2021 May 6 doi: 10.1016/j.euf.2021.04.020. PMID: 33967010
Incidence, risk factors and outcomes of urethral recurrence after radical cystectomy for bladder cancer: A systematic review and meta-analysis.
Laukhtina E, Mori K, D Andrea D, Moschini M, Abufaraj M, Soria F, Mari A, Krajewski W, Albisinni S, Teoh JY, Quhal F, Sari Motlagh R, Mostafaei H, Katayama S, Grossmann NС, Rajwa P, Enikeev D, Zimmermann K, Fajkovic H, Glybochko P, Shariat SF, Pradere B; European Association of Urology–Young Academic Urologists Urothelial Carcinoma Working Group (EAU-YAU)
Urol Oncol 2021 Dec;39(12):806-815. Epub 2021 Jul 13 doi: 10.1016/j.urolonc.2021.06.009. PMID: 34266740
A systematic review and meta-analysis on complications of transanal total mesorectal excision.
An Y, Roodbeen SX, Talboom K, Tanis PJ, Bemelman WA, Hompes R
Colorectal Dis 2021 Oct;23(10):2527-2538. Epub 2021 Jul 11 doi: 10.1111/codi.15792. PMID: 34174138
Ureteral involvement by metastatic malignant disease.
Hu J, Deng J, Guo J, Fu B
Clin Exp Metastasis 2019 Dec;36(6):499-509. Epub 2019 Aug 24 doi: 10.1007/s10585-019-09989-8. PMID: 31446521
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...