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Refractory Sarcoma

MedGen UID:
1655780
Concept ID:
C4724971
Neoplastic Process

Definition

A sarcoma that does not respond to treatment. [from NCI]

Professional guidelines

PubMed

Huang PW, Chou WC, Shen WC, Hung CY, Huang KG, Su YL, Lu CH, Liu CT, Chang YS, Liau CT
Asia Pac J Clin Oncol 2018 Aug;14(4):353-360. Epub 2018 Jun 13 doi: 10.1111/ajco.13029. PMID: 29900662
Ni JY, Sun HL, Chen YT, Luo JH, Wang WD, Jiang XY, Chen D, Xu LF
J Cancer Res Clin Oncol 2018 Jan;144(1):157-163. Epub 2017 Oct 9 doi: 10.1007/s00432-017-2530-3. PMID: 28993945
Kurzrock R
Mol Cancer Ther 2007 May;6(5):1477. Epub 2007 May 4 doi: 10.1158/1535-7163.MCT-07-0255. PMID: 17483434

Recent clinical studies

Etiology

Huang H, Zhang H, Cao B
Thorac Cancer 2024 Feb;15(5):427-433. Epub 2024 Jan 11 doi: 10.1111/1759-7714.15208. PMID: 38211967Free PMC Article
Ju HY, Park M, Lee JA, Park HJ, Park SY, Kim JH, Kang HG, Yang HC, Park BK
Cancer Res Treat 2022 Apr;54(2):563-571. Epub 2021 Jun 14 doi: 10.4143/crt.2021.178. PMID: 34126703Free PMC Article
Huang PW, Chou WC, Shen WC, Hung CY, Huang KG, Su YL, Lu CH, Liu CT, Chang YS, Liau CT
Asia Pac J Clin Oncol 2018 Aug;14(4):353-360. Epub 2018 Jun 13 doi: 10.1111/ajco.13029. PMID: 29900662
Wagner LM, Fouladi M, Ahmed A, Krailo MD, Weigel B, DuBois SG, Doyle LA, Chen H, Blaney SM
Pediatr Blood Cancer 2015 Mar;62(3):440-4. Epub 2014 Nov 28 doi: 10.1002/pbc.25334. PMID: 25446280Free PMC Article
Van Winkle P, Angiolillo A, Krailo M, Cheung YK, Anderson B, Davenport V, Reaman G, Cairo MS
Pediatr Blood Cancer 2005 Apr;44(4):338-47. doi: 10.1002/pbc.20227. PMID: 15503297

Diagnosis

Huang H, Zhang H, Cao B
Thorac Cancer 2024 Feb;15(5):427-433. Epub 2024 Jan 11 doi: 10.1111/1759-7714.15208. PMID: 38211967Free PMC Article
Ju HY, Park M, Lee JA, Park HJ, Park SY, Kim JH, Kang HG, Yang HC, Park BK
Cancer Res Treat 2022 Apr;54(2):563-571. Epub 2021 Jun 14 doi: 10.4143/crt.2021.178. PMID: 34126703Free PMC Article
Huang PW, Chou WC, Shen WC, Hung CY, Huang KG, Su YL, Lu CH, Liu CT, Chang YS, Liau CT
Asia Pac J Clin Oncol 2018 Aug;14(4):353-360. Epub 2018 Jun 13 doi: 10.1111/ajco.13029. PMID: 29900662

Therapy

D'Angelo SP, Richards AL, Conley AP, Woo HJ, Dickson MA, Gounder M, Kelly C, Keohan ML, Movva S, Thornton K, Rosenbaum E, Chi P, Nacev B, Chan JE, Slotkin EK, Kiesler H, Adamson T, Ling L, Rao P, Patel S, Livingston JA, Singer S, Agaram NP, Antonescu CR, Koff A, Erinjeri JP, Hwang S, Qin LX, Donoghue MTA, Tap WD
Nat Commun 2022 Jun 16;13(1):3477. doi: 10.1038/s41467-022-30874-8. PMID: 35710741Free PMC Article
Ju HY, Park M, Lee JA, Park HJ, Park SY, Kim JH, Kang HG, Yang HC, Park BK
Cancer Res Treat 2022 Apr;54(2):563-571. Epub 2021 Jun 14 doi: 10.4143/crt.2021.178. PMID: 34126703Free PMC Article
Simmons C, Deyell RJ, MacNeill AJ, Vera-Badillo FE, Smrke A, Abdul Razak AR, Banerji S, McLeod D, Noujaim J
Int J Cancer 2021 Nov 1;149(9):1691-1704. Epub 2021 Aug 4 doi: 10.1002/ijc.33723. PMID: 34213775
Takahashi R, Ishibashi Y, Hiraoka K, Matsueda S, Kawano K, Kawahara A, Kage M, Ohshima K, Yamanaka R, Shichijo S, Shirouzu K, Itoh K, Sasada T
Cancer Sci 2013 Oct;104(10):1285-94. Epub 2013 Aug 6 doi: 10.1111/cas.12226. PMID: 23829867Free PMC Article
Subbiah V, Kurzrock R
Curr Opin Oncol 2011 Jul;23(4):352-60. doi: 10.1097/CCO.0b013e3283477a94. PMID: 21519259

Prognosis

D'Angelo SP, Richards AL, Conley AP, Woo HJ, Dickson MA, Gounder M, Kelly C, Keohan ML, Movva S, Thornton K, Rosenbaum E, Chi P, Nacev B, Chan JE, Slotkin EK, Kiesler H, Adamson T, Ling L, Rao P, Patel S, Livingston JA, Singer S, Agaram NP, Antonescu CR, Koff A, Erinjeri JP, Hwang S, Qin LX, Donoghue MTA, Tap WD
Nat Commun 2022 Jun 16;13(1):3477. doi: 10.1038/s41467-022-30874-8. PMID: 35710741Free PMC Article
Ju HY, Park M, Lee JA, Park HJ, Park SY, Kim JH, Kang HG, Yang HC, Park BK
Cancer Res Treat 2022 Apr;54(2):563-571. Epub 2021 Jun 14 doi: 10.4143/crt.2021.178. PMID: 34126703Free PMC Article
Ni JY, Sun HL, Chen YT, Luo JH, Wang WD, Jiang XY, Chen D, Xu LF
J Cancer Res Clin Oncol 2018 Jan;144(1):157-163. Epub 2017 Oct 9 doi: 10.1007/s00432-017-2530-3. PMID: 28993945
Miwa S, Nishida H, Tanzawa Y, Takeuchi A, Hayashi K, Yamamoto N, Mizukoshi E, Nakamoto Y, Kaneko S, Tsuchiya H
Cancer 2017 May 1;123(9):1576-1584. Epub 2017 Feb 27 doi: 10.1002/cncr.30606. PMID: 28241093
Subbiah V, Kurzrock R
Curr Opin Oncol 2011 Jul;23(4):352-60. doi: 10.1097/CCO.0b013e3283477a94. PMID: 21519259

Clinical prediction guides

D'Angelo SP, Richards AL, Conley AP, Woo HJ, Dickson MA, Gounder M, Kelly C, Keohan ML, Movva S, Thornton K, Rosenbaum E, Chi P, Nacev B, Chan JE, Slotkin EK, Kiesler H, Adamson T, Ling L, Rao P, Patel S, Livingston JA, Singer S, Agaram NP, Antonescu CR, Koff A, Erinjeri JP, Hwang S, Qin LX, Donoghue MTA, Tap WD
Nat Commun 2022 Jun 16;13(1):3477. doi: 10.1038/s41467-022-30874-8. PMID: 35710741Free PMC Article
Liu C, Cui Q, Guo J, Li D, Zeng Y
Pathol Oncol Res 2014 Apr;20(2):229-34. Epub 2014 Jan 21 doi: 10.1007/s12253-013-9673-6. PMID: 24446082
Takahashi R, Ishibashi Y, Hiraoka K, Matsueda S, Kawano K, Kawahara A, Kage M, Ohshima K, Yamanaka R, Shichijo S, Shirouzu K, Itoh K, Sasada T
Cancer Sci 2013 Oct;104(10):1285-94. Epub 2013 Aug 6 doi: 10.1111/cas.12226. PMID: 23829867Free PMC Article
Subbiah V, Kurzrock R
Curr Opin Oncol 2011 Jul;23(4):352-60. doi: 10.1097/CCO.0b013e3283477a94. PMID: 21519259
Wiedemann GJ, Robins HI, Katschinski DM, Mentzel M, D'Oleire F, Kutz M, Wagner T
Anticancer Res 1997 Jul-Aug;17(4B):2899-902. PMID: 9329558

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