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Benign familial mesial temporal lobe epilepsy

MedGen UID:
1659458
Concept ID:
C4749273
Disease or Syndrome
Synonyms: Benign FMTLE; Benign FMTLE (familial mesial temporal lobe epilepsy)
SNOMED CT: Benign familial mesial temporal lobe epilepsy (770405003); Benign FMTLE (familial mesial temporal lobe epilepsy) (770405003)
Modes of inheritance:
 
Orphanet: ORPHA163717

Definition

Rare epilepsy with characteristics of seizures with viscerosensory or experiential auras, onset in adolescence or early adulthood and good prognosis. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign familial mesial temporal lobe epilepsy

Recent clinical studies

Etiology

Fanciulli M, Di Bonaventura C, Egeo G, Fattouch J, Dazzo E, Radovic S, Spadotto A, Giallonardo AT, Nobile C
Epilepsy Res 2014 Feb;108(2):232-40. Epub 2013 Nov 18 doi: 10.1016/j.eplepsyres.2013.11.002. PMID: 24315020
Hedera P, Blair MA, Andermann E, Andermann F, D'Agostino D, Taylor KA, Chahine L, Pandolfo M, Bradford Y, Haines JL, Abou-Khalil B
Neurology 2007 Jun 12;68(24):2107-12. Epub 2007 Mar 21 doi: 10.1212/01.wnl.0000261246.75977.89. PMID: 17377072
Alessio A, Kobayashi E, Damasceno BP, Lopes-Cendes I, Cendes F
Epilepsy Behav 2004 Dec;5(6):981-7. doi: 10.1016/j.yebeh.2004.08.018. PMID: 15582848
Shinnar S, Pellock JM, Berg AT, O'Dell C, Driscoll SM, Maytal J, Moshe SL, DeLorenzo RJ
Epilepsia 2001 Jan;42(1):47-53. doi: 10.1046/j.1528-1157.2001.10000.x. PMID: 11207784
Kobayashi E, Lopes-Cendes I, Guerreiro CA, Sousa SC, Guerreiro MM, Cendes F
Neurology 2001 Jan 23;56(2):166-72. doi: 10.1212/wnl.56.2.166. PMID: 11160950

Diagnosis

Fanciulli M, Di Bonaventura C, Egeo G, Fattouch J, Dazzo E, Radovic S, Spadotto A, Giallonardo AT, Nobile C
Epilepsy Res 2014 Feb;108(2):232-40. Epub 2013 Nov 18 doi: 10.1016/j.eplepsyres.2013.11.002. PMID: 24315020
Crompton DE, Scheffer IE, Taylor I, Cook MJ, McKelvie PA, Vears DF, Lawrence KM, McMahon JM, Grinton BE, McIntosh AM, Berkovic SF
Brain 2010 Nov;133(11):3221-31. Epub 2010 Sep 23 doi: 10.1093/brain/awq251. PMID: 20864493
Gambardella A, Labate A, Giallonardo A, Aguglia U
Epilepsia 2009 May;50 Suppl 5:55-7. doi: 10.1111/j.1528-1167.2009.02123.x. PMID: 19469849
Labate A, Ventura P, Gambardella A, Le Piane E, Colosimo E, Leggio U, Ambrosio R, Condino F, Messina D, Lanza P, Aguglia U, Quattrone A
Neurology 2006 Feb 28;66(4):562-5. doi: 10.1212/01.wnl.0000198208.59347.96. PMID: 16505312
Kobayashi E, Lopes-Cendes I, Guerreiro CA, Sousa SC, Guerreiro MM, Cendes F
Neurology 2001 Jan 23;56(2):166-72. doi: 10.1212/wnl.56.2.166. PMID: 11160950

Prognosis

Labate A, Gambardella A, Andermann E, Aguglia U, Cendes F, Berkovic SF, Andermann F
Nat Rev Neurol 2011 Apr;7(4):237-40. Epub 2011 Jan 25 doi: 10.1038/nrneurol.2010.212. PMID: 21263461
Crompton DE, Scheffer IE, Taylor I, Cook MJ, McKelvie PA, Vears DF, Lawrence KM, McMahon JM, Grinton BE, McIntosh AM, Berkovic SF
Brain 2010 Nov;133(11):3221-31. Epub 2010 Sep 23 doi: 10.1093/brain/awq251. PMID: 20864493
Hedera P, Blair MA, Andermann E, Andermann F, D'Agostino D, Taylor KA, Chahine L, Pandolfo M, Bradford Y, Haines JL, Abou-Khalil B
Neurology 2007 Jun 12;68(24):2107-12. Epub 2007 Mar 21 doi: 10.1212/01.wnl.0000261246.75977.89. PMID: 17377072
Kobayashi E, Lopes-Cendes I, Guerreiro CA, Sousa SC, Guerreiro MM, Cendes F
Neurology 2001 Jan 23;56(2):166-72. doi: 10.1212/wnl.56.2.166. PMID: 11160950

Clinical prediction guides

Fanciulli M, Di Bonaventura C, Egeo G, Fattouch J, Dazzo E, Radovic S, Spadotto A, Giallonardo AT, Nobile C
Epilepsy Res 2014 Feb;108(2):232-40. Epub 2013 Nov 18 doi: 10.1016/j.eplepsyres.2013.11.002. PMID: 24315020
Labate A, Gambardella A, Andermann E, Aguglia U, Cendes F, Berkovic SF, Andermann F
Nat Rev Neurol 2011 Apr;7(4):237-40. Epub 2011 Jan 25 doi: 10.1038/nrneurol.2010.212. PMID: 21263461
Crompton DE, Scheffer IE, Taylor I, Cook MJ, McKelvie PA, Vears DF, Lawrence KM, McMahon JM, Grinton BE, McIntosh AM, Berkovic SF
Brain 2010 Nov;133(11):3221-31. Epub 2010 Sep 23 doi: 10.1093/brain/awq251. PMID: 20864493
Hedera P, Blair MA, Andermann E, Andermann F, D'Agostino D, Taylor KA, Chahine L, Pandolfo M, Bradford Y, Haines JL, Abou-Khalil B
Neurology 2007 Jun 12;68(24):2107-12. Epub 2007 Mar 21 doi: 10.1212/01.wnl.0000261246.75977.89. PMID: 17377072
Kobayashi E, Lopes-Cendes I, Guerreiro CA, Sousa SC, Guerreiro MM, Cendes F
Neurology 2001 Jan 23;56(2):166-72. doi: 10.1212/wnl.56.2.166. PMID: 11160950

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