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Locally Advanced Unresectable Prostate Carcinoma

MedGen UID:
1659574
Concept ID:
C4744716
Neoplastic Process

Definition

A prostatic carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes and is not amenable to surgical resection. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Patel P, Alrifai D, McDonald F, Forster M; AstraZeneca UK Limited
Br J Cancer 2020 Dec;123(Suppl 1):18-27. doi: 10.1038/s41416-020-01071-5. PMID: 33293672Free PMC Article
Shelley MD, Cleves A, Wilt TJ, Mason MD
BJU Int 2011 Jul;108(2):168-79. doi: 10.1111/j.1464-410X.2011.10341.x. PMID: 21718430

Recent clinical studies

Etiology

Tsakiridis T, Pond GR, Wright J, Ellis PM, Ahmed N, Abdulkarim B, Roa W, Robinson A, Swaminath A, Okawara G, Wierzbicki M, Valdes M, Levine M
JAMA Oncol 2021 Sep 1;7(9):1333-1341. doi: 10.1001/jamaoncol.2021.2328. PMID: 34323924Free PMC Article
Grivas P, Loriot Y, Morales-Barrera R, Teo MY, Zakharia Y, Feyerabend S, Vogelzang NJ, Grande E, Adra N, Alva A, Necchi A, Rodriguez-Vida A, Gupta S, Josephs DH, Srinivas S, Wride K, Thomas D, Simmons A, Loehr A, Dusek RL, Nepert D, Chowdhury S
BMC Cancer 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z. PMID: 34030643Free PMC Article
Shelley MD, Cleves A, Wilt TJ, Mason MD
BJU Int 2011 Jul;108(2):168-79. doi: 10.1111/j.1464-410X.2011.10341.x. PMID: 21718430
Shelley M, Cleves A, Wilt TJ, Mason M
Cochrane Database Syst Rev 2011 Apr 13;(4):CD008976. doi: 10.1002/14651858.CD008976.pub2. PMID: 21491413
Brierly RD, O'Brien TS
Urol Int 2008;80(1):13-8. Epub 2008 Jan 18 doi: 10.1159/000111723. PMID: 18204227

Diagnosis

Soper MS, Iganej S, Thompson LD
Head Neck 2014 Jan;36(1):E4-7. Epub 2013 Sep 17 doi: 10.1002/hed.23383. PMID: 23720164

Therapy

Tsakiridis T, Pond GR, Wright J, Ellis PM, Ahmed N, Abdulkarim B, Roa W, Robinson A, Swaminath A, Okawara G, Wierzbicki M, Valdes M, Levine M
JAMA Oncol 2021 Sep 1;7(9):1333-1341. doi: 10.1001/jamaoncol.2021.2328. PMID: 34323924Free PMC Article
Grivas P, Loriot Y, Morales-Barrera R, Teo MY, Zakharia Y, Feyerabend S, Vogelzang NJ, Grande E, Adra N, Alva A, Necchi A, Rodriguez-Vida A, Gupta S, Josephs DH, Srinivas S, Wride K, Thomas D, Simmons A, Loehr A, Dusek RL, Nepert D, Chowdhury S
BMC Cancer 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z. PMID: 34030643Free PMC Article
Shelley MD, Cleves A, Wilt TJ, Mason MD
BJU Int 2011 Jul;108(2):168-79. doi: 10.1111/j.1464-410X.2011.10341.x. PMID: 21718430
Shelley M, Cleves A, Wilt TJ, Mason M
Cochrane Database Syst Rev 2011 Apr 13;(4):CD008976. doi: 10.1002/14651858.CD008976.pub2. PMID: 21491413
Bunn PA Jr
Semin Oncol 1998 Aug;25(4 Suppl 9):55-61. PMID: 9728586

Prognosis

Grivas P, Loriot Y, Morales-Barrera R, Teo MY, Zakharia Y, Feyerabend S, Vogelzang NJ, Grande E, Adra N, Alva A, Necchi A, Rodriguez-Vida A, Gupta S, Josephs DH, Srinivas S, Wride K, Thomas D, Simmons A, Loehr A, Dusek RL, Nepert D, Chowdhury S
BMC Cancer 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z. PMID: 34030643Free PMC Article
Soper MS, Iganej S, Thompson LD
Head Neck 2014 Jan;36(1):E4-7. Epub 2013 Sep 17 doi: 10.1002/hed.23383. PMID: 23720164
Shelley MD, Cleves A, Wilt TJ, Mason MD
BJU Int 2011 Jul;108(2):168-79. doi: 10.1111/j.1464-410X.2011.10341.x. PMID: 21718430
Shelley M, Cleves A, Wilt TJ, Mason M
Cochrane Database Syst Rev 2011 Apr 13;(4):CD008976. doi: 10.1002/14651858.CD008976.pub2. PMID: 21491413

Clinical prediction guides

Grivas P, Loriot Y, Morales-Barrera R, Teo MY, Zakharia Y, Feyerabend S, Vogelzang NJ, Grande E, Adra N, Alva A, Necchi A, Rodriguez-Vida A, Gupta S, Josephs DH, Srinivas S, Wride K, Thomas D, Simmons A, Loehr A, Dusek RL, Nepert D, Chowdhury S
BMC Cancer 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z. PMID: 34030643Free PMC Article
Lasalvia-Prisco E, Goldschmidt P, Galmarini F, Cucchi S, Vázquez J, Aghazarian M, Lasalvia-Galante E, Golomar W, Gordon W
Med Oncol 2012 Dec;29(5):3626-33. Epub 2012 Jul 19 doi: 10.1007/s12032-012-0301-1. PMID: 22810591Free PMC Article
Shelley MD, Cleves A, Wilt TJ, Mason MD
BJU Int 2011 Jul;108(2):168-79. doi: 10.1111/j.1464-410X.2011.10341.x. PMID: 21718430
Brierly RD, O'Brien TS
Urol Int 2008;80(1):13-8. Epub 2008 Jan 18 doi: 10.1159/000111723. PMID: 18204227
Lindsley KL, Cho P, Stelzer KJ, Koh WJ, Austin-Seymour M, Russell KJ, Laramore GE, Griffin TW
Bull Cancer Radiother 1996;83 Suppl:78s-86s. doi: 10.1016/0924-4212(96)84889-4. PMID: 8949756

Recent systematic reviews

Shelley M, Cleves A, Wilt TJ, Mason M
Cochrane Database Syst Rev 2011 Apr 13;(4):CD008976. doi: 10.1002/14651858.CD008976.pub2. PMID: 21491413

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