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Supratentorial Pleomorphic Xanthoastrocytoma

MedGen UID:
1660183
•Concept ID:
C4744526
•
Neoplastic Process

Definition

A pleomorphic xanthoastrocytoma that arises from the supratentorial region of the brain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSupratentorial Pleomorphic Xanthoastrocytoma

Professional guidelines

PubMed

Clinical Features, Treatment and Outcome of Childhood Glial Tumors.
Kara B, Ertan K, Karabagli P, Karabagli H, Yavas G, Caglayan AO, Koksal Y
Turk Neurosurg 2022;32(1):135-142. doi: 10.5137/1019-5149.JTN.34801-21.2. PMID: 34751424
Hub biomarkers for the diagnosis and treatment of glioblastoma based on microarray technology.
Cui K, Chen JH, Zou YF, Zhang SY, Wu B, Jing K, Li LW, Xia L, Sun C, Dong YL
Technol Cancer Res Treat 2021 Jan-Dec;20:1533033821990368. doi: 10.1177/1533033821990368. PMID: 34018447Free PMC Article
Supratentorial low-grade diffuse astrocytoma: medical management.
Ajlan A, Recht L
Semin Oncol 2014 Aug;41(4):446-457. Epub 2014 Jul 1 doi: 10.1053/j.seminoncol.2014.06.013. PMID: 25173138

Recent clinical studies

Etiology

Diagnostic accuracy of diffusion weighted imaging for differentiation of supratentorial pilocytic astrocytoma and pleomorphic xanthoastrocytoma.
She D, Liu J, Zeng Z, Xing Z, Cao D
Neuroradiology 2018 Jul;60(7):725-733. Epub 2018 May 24 doi: 10.1007/s00234-018-2036-y. PMID: 29797290Free PMC Article
Recurrent copy number alterations in low-grade and anaplastic pleomorphic xanthoastrocytoma with and without BRAF V600E mutation.
Vaubel RA, Caron AA, Yamada S, Decker PA, Eckel Passow JE, Rodriguez FJ, Nageswara Rao AA, Lachance D, Parney I, Jenkins R, Giannini C
Brain Pathol 2018 Mar;28(2):172-182. Epub 2017 Apr 2 doi: 10.1111/bpa.12495. PMID: 28181325Free PMC Article
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
Pleomorphic xanthoastrocytoma of childhood: MR imaging and diffusion MR imaging features.
Moore W, Mathis D, Gargan L, Bowers DC, Klesse LJ, Margraf L, Koral K
AJNR Am J Neuroradiol 2014 Nov-Dec;35(11):2192-6. Epub 2014 Jul 3 doi: 10.3174/ajnr.A4011. PMID: 24994821Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318

Diagnosis

Pleomorphic xanthoastrocytoma, anaplastic pleomorphic xanthoastrocytoma, and epithelioid glioblastoma: Case series with clinical characteristics, molecular features and progression relationship.
Lin Z, Yang R, Zheng H, Li Z, Yi G, Wu Q, Yang C, Huang G
Clin Neurol Neurosurg 2022 Oct;221:107379. Epub 2022 Jul 21 doi: 10.1016/j.clineuro.2022.107379. PMID: 35932588
Supratentorial Tumors in Pediatric Patients.
Zamora C, Huisman TA, Izbudak I
Neuroimaging Clin N Am 2017 Feb;27(1):39-67. doi: 10.1016/j.nic.2016.08.003. PMID: 27889023
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
High-grade gliomas in children.
Cage TA, Mueller S, Haas-Kogan D, Gupta N
Neurosurg Clin N Am 2012 Jul;23(3):515-23. Epub 2012 Jun 5 doi: 10.1016/j.nec.2012.04.007. PMID: 22748663
Low-grade glial tumors: are they all the same?
Bristol RE
Semin Pediatr Neurol 2009 Mar;16(1):23-6. doi: 10.1016/j.spen.2009.03.002. PMID: 19410153

Therapy

Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial.
Todo T, Ito H, Ino Y, Ohtsu H, Ota Y, Shibahara J, Tanaka M
Nat Med 2022 Aug;28(8):1630-1639. Epub 2022 Jul 21 doi: 10.1038/s41591-022-01897-x. PMID: 35864254Free PMC Article
Stereotactic Cryodestruction of Gliomas.
Martynov BV, Kholyavin AI, Nizkovolos VB, Parfenov VE, Trufanov GE, Svistov DV
Prog Neurol Surg 2018;32:27-38. Epub 2018 Jul 10 doi: 10.1159/000469677. PMID: 29990971
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Pediatric glial tumors.
Cohen KJ, Broniscer A, Glod J
Curr Treat Options Oncol 2001 Dec;2(6):529-36. doi: 10.1007/s11864-001-0074-9. PMID: 12057098

Prognosis

Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
The role of surgery in grade II/III oligodendroglial tumors.
Thon N, Kreth FW, Tonn JC
CNS Oncol 2015;4(5):317-23. Epub 2015 Oct 19 doi: 10.2217/cns.15.26. PMID: 26478133Free PMC Article
Aggressive behavior and anaplasia in pleomorphic xanthoastrocytoma: a plea for a revision of the current WHO classification.
Kahramancetin N, Tihan T
CNS Oncol 2013 Nov;2(6):523-30. doi: 10.2217/cns.13.56. PMID: 25054822Free PMC Article
High-grade gliomas in children.
Cage TA, Mueller S, Haas-Kogan D, Gupta N
Neurosurg Clin N Am 2012 Jul;23(3):515-23. Epub 2012 Jun 5 doi: 10.1016/j.nec.2012.04.007. PMID: 22748663
Pediatric glial tumors.
Cohen KJ, Broniscer A, Glod J
Curr Treat Options Oncol 2001 Dec;2(6):529-36. doi: 10.1007/s11864-001-0074-9. PMID: 12057098

Clinical prediction guides

Clinical and Epidemiological Study of Intracranial Tumors in Children and Identification of Diagnostic Biomarkers for the Most Common Tumor Subtype and Their Relationship with the Immune Microenvironment Through Bioinformatics Analysis.
Wang G, Jia Y, Ye Y, Kang E, Chen H, Wang J, He X
J Mol Neurosci 2022 Jun;72(6):1208-1223. Epub 2022 Mar 28 doi: 10.1007/s12031-022-02003-z. PMID: 35347632
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Recurrent copy number alterations in low-grade and anaplastic pleomorphic xanthoastrocytoma with and without BRAF V600E mutation.
Vaubel RA, Caron AA, Yamada S, Decker PA, Eckel Passow JE, Rodriguez FJ, Nageswara Rao AA, Lachance D, Parney I, Jenkins R, Giannini C
Brain Pathol 2018 Mar;28(2):172-182. Epub 2017 Apr 2 doi: 10.1111/bpa.12495. PMID: 28181325Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Aggressive behavior and anaplasia in pleomorphic xanthoastrocytoma: a plea for a revision of the current WHO classification.
Kahramancetin N, Tihan T
CNS Oncol 2013 Nov;2(6):523-30. doi: 10.2217/cns.13.56. PMID: 25054822Free PMC Article

Recent systematic reviews

The role of radiation therapy in treatment of adults with newly diagnosed glioblastoma multiforme: a systematic review and evidence-based clinical practice guideline update.
Ziu M, Kim BYS, Jiang W, Ryken T, Olson JJ
J Neurooncol 2020 Nov;150(2):215-267. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03612-7. PMID: 33215344
Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update.
Domino JS, Ormond DR, Germano IM, Sami M, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):121-142. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03606-5. PMID: 33215341
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article

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