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Malignant Skull Neoplasm

MedGen UID:
1662558
•Concept ID:
C2062986
•
Neoplastic Process

Definition

A primary or metastatic malignant neoplasm that affects the bones and structures of the skull. [from NCI]

Professional guidelines

PubMed

EANO guideline on the diagnosis and treatment of vestibular schwannoma.
Goldbrunner R, Weller M, Regis J, Lund-Johansen M, Stavrinou P, Reuss D, Evans DG, Lefranc F, Sallabanda K, Falini A, Axon P, Sterkers O, Fariselli L, Wick W, Tonn JC
Neuro Oncol 2020 Jan 11;22(1):31-45. doi: 10.1093/neuonc/noz153. PMID: 31504802Free PMC Article
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455
Ameloblastoma: current etiopathological concepts and management.
Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO
Oral Dis 2018 Apr;24(3):307-316. Epub 2017 Mar 9 doi: 10.1111/odi.12646. PMID: 28142213

Recent clinical studies

Etiology

Radiation therapy strategies for skull-base malignancies.
Palmer JD, Gamez ME, Ranta K, Ruiz-Garcia H, Peterson JL, Blakaj DM, Prevedello D, Carrau R, Mahajan A, Chaichana KL, Trifiletti DM
J Neurooncol 2020 Dec;150(3):445-462. Epub 2020 Aug 12 doi: 10.1007/s11060-020-03569-7. PMID: 32785868
Fibrous dysplasia imitating malignancy.
Martini M, Klausing A, Heim N, Fischer HP, Sommer A, Reich RH
J Craniomaxillofac Surg 2018 Aug;46(8):1313-1319. Epub 2018 May 12 doi: 10.1016/j.jcms.2018.05.019. PMID: 29859820
A brief report of plexiform neurofibroma.
Khajavi M, Khoshsirat S, Ahangarnazari L, Majdinasab N
Curr Probl Cancer 2018 Mar-Apr;42(2):256-260. Epub 2018 Jan 10 doi: 10.1016/j.currproblcancer.2018.01.007. PMID: 29449010
Skull base chordoma.
Mendenhall WM, Mendenhall CM, Lewis SB, Villaret DB, Mendenhall NP
Head Neck 2005 Feb;27(2):159-65. doi: 10.1002/hed.20144. PMID: 15641104
Malignant glomus tumors.
Manolidis S, Shohet JA, Jackson CG, Glasscock ME 3rd
Laryngoscope 1999 Jan;109(1):30-4. doi: 10.1097/00005537-199901000-00007. PMID: 9917036

Diagnosis

Treatment Options for Recurrent Anterior Skull Base Tumors.
Orlandi E, Iacovelli NA, Ingargiola R, Resteghini C, Bossi P, Licitra L, Ferrari M, Nicolai P
Adv Otorhinolaryngol 2020;84:231-245. Epub 2020 Jul 30 doi: 10.1159/000457942. PMID: 32731228
A brief report of plexiform neurofibroma.
Khajavi M, Khoshsirat S, Ahangarnazari L, Majdinasab N
Curr Probl Cancer 2018 Mar-Apr;42(2):256-260. Epub 2018 Jan 10 doi: 10.1016/j.currproblcancer.2018.01.007. PMID: 29449010
Primary intraosseous meningioma.
Elder JB, Atkinson R, Zee CS, Chen TC
Neurosurg Focus 2007;23(4):E13. doi: 10.3171/FOC-07/10/E13. PMID: 17961037
Temporal bone carcinoma.
Barrs DM
Otolaryngol Clin North Am 2001 Dec;34(6):1197-218, x. doi: 10.1016/s0030-6665(05)70374-1. PMID: 11728941
Temporal bone resection.
Willging JP, Pensak ML
Ear Nose Throat J 1991 Sep;70(9):612-7. PMID: 1743111

Therapy

Posttreatment Imaging Surveillance.
Farina D, Zorza I, Golemi S, Lombardi D, Borghesi A, Maroldi R, Ravanelli M
Adv Otorhinolaryngol 2020;84:218-230. Epub 2020 Jul 30 doi: 10.1159/000457941. PMID: 32731227
Management of squamous cell carcinomas of the skull-base.
Leonard CG, Padhye V, Witterick IJ
J Neurooncol 2020 Dec;150(3):377-386. Epub 2020 Jun 5 doi: 10.1007/s11060-020-03545-1. PMID: 32504403
Osteoradionecrosis of the skull base.
Leonetti JP, Weishaar JR, Gannon D, Harmon GA, Block A, Anderson DE
J Neurooncol 2020 Dec;150(3):477-482. Epub 2020 May 11 doi: 10.1007/s11060-020-03462-3. PMID: 32394326
Temporal bone malignancies.
Gidley PW, DeMonte F
Neurosurg Clin N Am 2013 Jan;24(1):97-110. doi: 10.1016/j.nec.2012.08.009. PMID: 23174361
Skull base chordomas.
Koutourousiou M, Snyderman CH, Fernandez-Miranda J, Gardner PA
Otolaryngol Clin North Am 2011 Oct;44(5):1155-71. Epub 2011 Jul 21 doi: 10.1016/j.otc.2011.06.002. PMID: 21978899

Prognosis

Fibrous dysplasia imitating malignancy.
Martini M, Klausing A, Heim N, Fischer HP, Sommer A, Reich RH
J Craniomaxillofac Surg 2018 Aug;46(8):1313-1319. Epub 2018 May 12 doi: 10.1016/j.jcms.2018.05.019. PMID: 29859820
Survival, Morbidity, and Quality-of-Life Outcomes for Sinonasal and Ventral Skull Base Malignancies.
Kilic S, Kilic SS, Baredes S, Liu JK, Eloy JA
Otolaryngol Clin North Am 2017 Apr;50(2):467-480. Epub 2017 Feb 1 doi: 10.1016/j.otc.2016.12.018. PMID: 28160996
Intraosseous hemangiomas.
Valentini V, Nicolai G, Lorè B, Aboh IV
J Craniofac Surg 2008 Nov;19(6):1459-64. doi: 10.1097/SCS.0b013e318188a030. PMID: 19098533
Skull base chordoma.
Mendenhall WM, Mendenhall CM, Lewis SB, Villaret DB, Mendenhall NP
Head Neck 2005 Feb;27(2):159-65. doi: 10.1002/hed.20144. PMID: 15641104
Malignant glomus tumors.
Manolidis S, Shohet JA, Jackson CG, Glasscock ME 3rd
Laryngoscope 1999 Jan;109(1):30-4. doi: 10.1097/00005537-199901000-00007. PMID: 9917036

Clinical prediction guides

Meningiomas.
Ganz JC
Prog Brain Res 2022;268(1):163-190. Epub 2021 Dec 14 doi: 10.1016/bs.pbr.2021.10.031. PMID: 35074079
Squamous Cell Carcinoma and Its Variants.
Mani N, Shah JP
Adv Otorhinolaryngol 2020;84:124-136. Epub 2020 Jul 30 doi: 10.1159/000457932. PMID: 32731225
Reconstruction after open surgery for skull-base malignancies.
Hanasono MM
J Neurooncol 2020 Dec;150(3):469-475. Epub 2020 Feb 13 doi: 10.1007/s11060-019-03370-1. PMID: 32056144
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455
Staging of Sinonasal and Ventral Skull Base Malignancies.
Desai DD, Brandon BM, Perkins EL, Ebert CS, Zanation AM, Thorp BD
Otolaryngol Clin North Am 2017 Apr;50(2):257-271. doi: 10.1016/j.otc.2016.12.004. PMID: 28314399

Recent systematic reviews

Long-term outcomes in sinonasal squamous cell carcinoma arising from inverted papilloma: Systematic review.
Birkenbeuel JL, Pang JC, Lee A, Nguyen ES, Risbud A, Goshtasbi K, Abiri A, Lehrich BM, Tong CCL, Adappa ND, Palmer JN, Kuan EC
Head Neck 2022 Apr;44(4):1014-1029. Epub 2022 Feb 9 doi: 10.1002/hed.26995. PMID: 35141984
Cyst or Tumor? A systematic review and meta-analysis on the expression of p53 marker in Odontogenic Keratocysts.
Slusarenko da Silva Y, Stoelinga PJW, Grillo R, da Graça Naclério-Homem M
J Craniomaxillofac Surg 2021 Dec;49(12):1101-1106. Epub 2021 Sep 28 doi: 10.1016/j.jcms.2021.09.015. PMID: 34620539
Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis.
Hendra FN, Natsir Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T
Oral Dis 2019 Oct;25(7):1683-1696. Epub 2019 Jan 1 doi: 10.1111/odi.13014. PMID: 30548549
Extranasopharyngeal angiofibroma revisited.
Windfuhr JP, Vent J
Clin Otolaryngol 2018 Feb;43(1):199-222. Epub 2017 Aug 10 doi: 10.1111/coa.12939. PMID: 28714226
Laryngeal Verrucous Carcinoma.
Echanique KA, Desai SV, Marchiano E, Spinazzi EF, Strojan P, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2017 Jan;156(1):38-45. Epub 2016 Aug 9 doi: 10.1177/0194599816662631. PMID: 27484231

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