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Castration-Naive

MedGen UID:
1662664
Concept ID:
C4725114
Finding

Definition

A finding indicating that an advanced prostate carcinoma was not previously treated with androgen-deprivation therapy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCastration-Naive

Professional guidelines

PubMed

Belderbos BPS, de Wit R, Lolkema MPJ, Mathijssen RHJ, van Soest RJ
Ann Oncol 2019 Oct 1;30(10):1591-1600. doi: 10.1093/annonc/mdz210. PMID: 31340031
Hamilou Z, Baciarello G, Fizazi K
Eur Urol Focus 2017 Dec;3(6):518-521. Epub 2018 Feb 27 doi: 10.1016/j.euf.2018.02.004. PMID: 29500136
Mohler JL, Armstrong AJ, Bahnson RR, D'Amico AV, Davis BJ, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Hurwitz M, Kane CJ, Kawachi MH, Kuettel M, Lee RJ, Meeks JJ, Penson DF, Plimack ER, Pow-Sang JM, Raben D, Richey S, Roach M 3rd, Rosenfeld S, Schaeffer E, Skolarus TA, Small EJ, Sonpavde G, Srinivas S, Strope SA, Tward J, Shead DA, Freedman-Cass DA
J Natl Compr Canc Netw 2016 Jan;14(1):19-30. doi: 10.6004/jnccn.2016.0004. PMID: 26733552

Recent clinical studies

Etiology

Chung C, Abboud K
Am J Health Syst Pharm 2022 Jul 22;79(15):1224-1235. doi: 10.1093/ajhp/zxac105. PMID: 35390118
Freedland SJ, Ke X, Lafeuille MH, Romdhani H, Kinkead F, Lefebvre P, Petrilla A, Pulungan Z, Kim S, D'Andrea DM, Francis P, Ryan CJ
Curr Med Res Opin 2021 Apr;37(4):609-622. Epub 2021 Feb 13 doi: 10.1080/03007995.2021.1879753. PMID: 33476184
Xu L, Pachynski RK
Curr Urol Rep 2018 Aug 13;19(10):79. doi: 10.1007/s11934-018-0835-7. PMID: 30105573
Gillessen S, Attard G, Beer TM, Beltran H, Bossi A, Bristow R, Carver B, Castellano D, Chung BH, Clarke N, Daugaard G, Davis ID, de Bono J, Borges Dos Reis R, Drake CG, Eeles R, Efstathiou E, Evans CP, Fanti S, Feng F, Fizazi K, Frydenberg M, Gleave M, Halabi S, Heidenreich A, Higano CS, James N, Kantoff P, Kellokumpu-Lehtinen PL, Khauli RB, Kramer G, Logothetis C, Maluf F, Morgans AK, Morris MJ, Mottet N, Murthy V, Oh W, Ost P, Padhani AR, Parker C, Pritchard CC, Roach M, Rubin MA, Ryan C, Saad F, Sartor O, Scher H, Sella A, Shore N, Smith M, Soule H, Sternberg CN, Suzuki H, Sweeney C, Sydes MR, Tannock I, Tombal B, Valdagni R, Wiegel T, Omlin A
Eur Urol 2018 Feb;73(2):178-211. Epub 2017 Jun 24 doi: 10.1016/j.eururo.2017.06.002. PMID: 28655541
Mohler JL, Armstrong AJ, Bahnson RR, D'Amico AV, Davis BJ, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Hurwitz M, Kane CJ, Kawachi MH, Kuettel M, Lee RJ, Meeks JJ, Penson DF, Plimack ER, Pow-Sang JM, Raben D, Richey S, Roach M 3rd, Rosenfeld S, Schaeffer E, Skolarus TA, Small EJ, Sonpavde G, Srinivas S, Strope SA, Tward J, Shead DA, Freedman-Cass DA
J Natl Compr Canc Netw 2016 Jan;14(1):19-30. doi: 10.6004/jnccn.2016.0004. PMID: 26733552

Diagnosis

Freedland SJ, Ke X, Lafeuille MH, Romdhani H, Kinkead F, Lefebvre P, Petrilla A, Pulungan Z, Kim S, D'Andrea DM, Francis P, Ryan CJ
Curr Med Res Opin 2021 Apr;37(4):609-622. Epub 2021 Feb 13 doi: 10.1080/03007995.2021.1879753. PMID: 33476184
Kwan EM, Thangasamy IA, Teh J, Alghazo O, Sathianathen NJ, Lawrentschuk N, Azad AA
World J Urol 2021 Feb;39(2):339-348. Epub 2020 Jan 2 doi: 10.1007/s00345-019-03060-7. PMID: 31897602
Chiong E, Murphy DG, Akaza H, Buchan NC, Chung BH, Kanesvaran R, Khochikar M, Letran J, Lojanapiwat B, Ng CF, Ong T, Pu YS, Saad M, Schubach K, Türkeri L, Umbas R, Le Chuyen V, Williams S, Ye DW; ANZUP Cancer Trials Group, Davis ID
BJU Int 2019 Jan;123(1):22-34. Epub 2018 Aug 19 doi: 10.1111/bju.14489. PMID: 30019467
Gillessen S, Attard G, Beer TM, Beltran H, Bossi A, Bristow R, Carver B, Castellano D, Chung BH, Clarke N, Daugaard G, Davis ID, de Bono J, Borges Dos Reis R, Drake CG, Eeles R, Efstathiou E, Evans CP, Fanti S, Feng F, Fizazi K, Frydenberg M, Gleave M, Halabi S, Heidenreich A, Higano CS, James N, Kantoff P, Kellokumpu-Lehtinen PL, Khauli RB, Kramer G, Logothetis C, Maluf F, Morgans AK, Morris MJ, Mottet N, Murthy V, Oh W, Ost P, Padhani AR, Parker C, Pritchard CC, Roach M, Rubin MA, Ryan C, Saad F, Sartor O, Scher H, Sella A, Shore N, Smith M, Soule H, Sternberg CN, Suzuki H, Sweeney C, Sydes MR, Tannock I, Tombal B, Valdagni R, Wiegel T, Omlin A
Eur Urol 2018 Feb;73(2):178-211. Epub 2017 Jun 24 doi: 10.1016/j.eururo.2017.06.002. PMID: 28655541
Mohler JL, Armstrong AJ, Bahnson RR, D'Amico AV, Davis BJ, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Hurwitz M, Kane CJ, Kawachi MH, Kuettel M, Lee RJ, Meeks JJ, Penson DF, Plimack ER, Pow-Sang JM, Raben D, Richey S, Roach M 3rd, Rosenfeld S, Schaeffer E, Skolarus TA, Small EJ, Sonpavde G, Srinivas S, Strope SA, Tward J, Shead DA, Freedman-Cass DA
J Natl Compr Canc Netw 2016 Jan;14(1):19-30. doi: 10.6004/jnccn.2016.0004. PMID: 26733552

Therapy

Chung C, Abboud K
Am J Health Syst Pharm 2022 Jul 22;79(15):1224-1235. doi: 10.1093/ajhp/zxac105. PMID: 35390118
Kwan EM, Thangasamy IA, Teh J, Alghazo O, Sathianathen NJ, Lawrentschuk N, Azad AA
World J Urol 2021 Feb;39(2):339-348. Epub 2020 Jan 2 doi: 10.1007/s00345-019-03060-7. PMID: 31897602
Xu L, Pachynski RK
Curr Urol Rep 2018 Aug 13;19(10):79. doi: 10.1007/s11934-018-0835-7. PMID: 30105573
Hamilou Z, Baciarello G, Fizazi K
Eur Urol Focus 2017 Dec;3(6):518-521. Epub 2018 Feb 27 doi: 10.1016/j.euf.2018.02.004. PMID: 29500136
Ratta R, Grassi P, Fucà G, Verzoni E, Procopio G
Expert Rev Anticancer Ther 2017 Oct;17(10):879-881. Epub 2017 Sep 11 doi: 10.1080/14737140.2017.1374178. PMID: 28854837

Prognosis

Yildirim ÖA, Gündoğan C, Can C, Poyraz K, Erdur E, Kömek H
Ann Nucl Med 2021 May;35(5):540-548. Epub 2021 Feb 14 doi: 10.1007/s12149-021-01594-8. PMID: 33586097
Kwan EM, Thangasamy IA, Teh J, Alghazo O, Sathianathen NJ, Lawrentschuk N, Azad AA
World J Urol 2021 Feb;39(2):339-348. Epub 2020 Jan 2 doi: 10.1007/s00345-019-03060-7. PMID: 31897602
Vrachimis A, Ferentinos K, Demetriou E, Ioannides C, Zamboglou N
Hell J Nucl Med 2020 Sep-Dec;23(3):339-345. Epub 2020 Dec 14 doi: 10.1967/s002449912211. PMID: 33306762
Belderbos BPS, de Wit R, Lolkema MPJ, Mathijssen RHJ, van Soest RJ
Ann Oncol 2019 Oct 1;30(10):1591-1600. doi: 10.1093/annonc/mdz210. PMID: 31340031
Mohler JL, Armstrong AJ, Bahnson RR, D'Amico AV, Davis BJ, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Hurwitz M, Kane CJ, Kawachi MH, Kuettel M, Lee RJ, Meeks JJ, Penson DF, Plimack ER, Pow-Sang JM, Raben D, Richey S, Roach M 3rd, Rosenfeld S, Schaeffer E, Skolarus TA, Small EJ, Sonpavde G, Srinivas S, Strope SA, Tward J, Shead DA, Freedman-Cass DA
J Natl Compr Canc Netw 2016 Jan;14(1):19-30. doi: 10.6004/jnccn.2016.0004. PMID: 26733552

Clinical prediction guides

Yildirim ÖA, Gündoğan C, Can C, Poyraz K, Erdur E, Kömek H
Ann Nucl Med 2021 May;35(5):540-548. Epub 2021 Feb 14 doi: 10.1007/s12149-021-01594-8. PMID: 33586097
Kwan EM, Thangasamy IA, Teh J, Alghazo O, Sathianathen NJ, Lawrentschuk N, Azad AA
World J Urol 2021 Feb;39(2):339-348. Epub 2020 Jan 2 doi: 10.1007/s00345-019-03060-7. PMID: 31897602
Bilgetekin I, Basal FB, Cinkir HY, Esin E, Oksuzoglu B, Demirci U
J Coll Physicians Surg Pak 2020 Aug;30(8):815-821. doi: 10.29271/jcpsp.2020.08.815. PMID: 32893792
Belderbos BPS, de Wit R, Lolkema MPJ, Mathijssen RHJ, van Soest RJ
Ann Oncol 2019 Oct 1;30(10):1591-1600. doi: 10.1093/annonc/mdz210. PMID: 31340031
Schuurhuizen CSEW, Marino P, Braamse AMJ, Buffart LM, Joly F, Fizazi K, Habibian M, Boher JM, Soulie M, Oudard S, Konings IRHM, Verheul HMW, Dekker J, Gravis G
J Natl Compr Canc Netw 2018 Dec;16(12):1481-1488. doi: 10.6004/jnccn.2018.7069. PMID: 30545995

Recent systematic reviews

Sun G, Zhang X, Chen J, Liao B, Liu Z, Zhao J, Gao AC, Yang Y, Shu K, Liu J, Zhao P, Shen P, Zeng H
Urol Oncol 2018 Dec;36(12):505-517. Epub 2018 Oct 11 doi: 10.1016/j.urolonc.2018.09.005. PMID: 30316578

Supplemental Content

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