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Pituitary Gland Non-Hodgkin Lymphoma

MedGen UID:
1663782
•Concept ID:
C4744383
•
Neoplastic Process
Synonym: Primary Pituitary Gland Non-Hodgkin Lymphoma

Definition

A rare non-Hodgkin lymphoma that arises from the pituitary gland. The majority are diffuse large B-cell lymphomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary Gland Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Prospective study on the influence of disease or treatment on pituitary function in 31 children with acute leukemia and non-Hodgkin's lymphoma.
Mittler U, Mohnike K, Kluba U, Kröning G, Kapitza W, Aumann V, Röppnack R
Haematol Blood Transfus 1990;33:571-6. doi: 10.1007/978-3-642-74643-7_104. PMID: 2323657

Recent clinical studies

Etiology

Epidemiology of Cancer Among Chronic Kidney Disease Patients Compared to The General Population.
Atris A, Al Salmi I, Al Rahbi F, Al-Bahrani BJ, Hannawi S
Gulf J Oncolog 2022 May;1(39):7-15. PMID: 35695340
The incidence of secondary central nervous system involvement in patients with non-Hodgkin's lymphoma as detected by 18F-FDG PET/CT.
Akkas BE, Vural GU
Nucl Med Commun 2013 Jan;34(1):50-6. doi: 10.1097/MNM.0b013e32835aaa48. PMID: 23111376
Familial blood vessel tumors and subsequent cancers.
Ji J, Hemminki K
Ann Oncol 2007 Jul;18(7):1260-7. Epub 2007 Apr 10 doi: 10.1093/annonc/mdm092. PMID: 17426058
Cancer incidence after nasopharyngeal radium irradiation.
Ronckers CM, Van Leeuwen FE, Hayes RB, Verduijn PG, Stovall M, Land CE
Epidemiology 2002 Sep;13(5):552-60. doi: 10.1097/00001648-200209000-00011. PMID: 12192225
Cancer mortality after nasopharyngeal radium irradiation in the Netherlands: a cohort study.
Ronckers CM, Land CE, Verduijn PG, Hayes RB, Stovall M, van Leeuwen FE
J Natl Cancer Inst 2001 Jul 4;93(13):1021-7. doi: 10.1093/jnci/93.13.1021. PMID: 11438568

Diagnosis

Concomitant Primary CNS Lymphoma and FSH-Pituitary Adenoma Arising Within the Sella. Entirely Coincidental?
Ban VS, Chaudhary BR, Allinson K, Santarius T, Kirollos RW
Neurosurgery 2017 Jan 1;80(1):E170-E175. doi: 10.1093/neuros/nyw003. PMID: 28362886Free PMC Article
Pituitary lymphoma developing within pituitary adenoma.
Morita K, Nakamura F, Kamikubo Y, Mizuno N, Miyauchi M, Yamamoto G, Nannya Y, Ichikawa M, Kurokawa M
Int J Hematol 2012 Jun;95(6):721-4. Epub 2012 Apr 21 doi: 10.1007/s12185-012-1075-0. PMID: 22527852
T-cell lymphoblastic lymphoma/leukemia presenting as a pituitary mass lesion: a case report and review of the literature.
Wiens AL, Hagen MC, Bonnin JM, Rizzo KA
Neuropathology 2012 Dec;32(6):668-74. Epub 2012 Mar 21 doi: 10.1111/j.1440-1789.2012.01314.x. PMID: 22432597
Lymphoma metastasizing to the pituitary: an unusual presentation of a treatable disease.
Megan Ogilvie C, Payne S, Evanson J, Lister TA, Grossman AB
Pituitary 2005;8(2):139-46. doi: 10.1007/s11102-005-4535-1. PMID: 16379034
Pituitary lymphoma: a case report and literature review.
Mathiasen RA, Jarrahy R, Cha ST, Kovacs K, Herman VS, Ginsberg E, Shahinian HK
Pituitary 2000 May;2(4):283-7. doi: 10.1023/a:1009969417380. PMID: 11081150

Therapy

Autopsy case report of intravascular large B-cell lymphoma with neoplastic PD-L1 expression.
Sakakibara A, Inagaki Y, Imaoka E, Ishikawa E, Shimada S, Shimada K, Suzuki Y, Nakamura S, Satou A, Kohno K
J Clin Exp Hematop 2018 Mar 16;58(1):32-35. Epub 2018 Feb 8 doi: 10.3960/jslrt.17037. PMID: 29415979Free PMC Article
Diffuse large cell non-Hodgkin lymphoma with pituitary and bilateral adrenal involvement.
Wang XL, Lü ZH, Mu YM, Dou JT, Lu JM, Zhong WW, Pan CY
Intern Med J 2012 Mar;42(3):329-32. doi: 10.1111/j.1445-5994.2011.02691.x. PMID: 22432986
Cancer incidence after nasopharyngeal radium irradiation.
Ronckers CM, Van Leeuwen FE, Hayes RB, Verduijn PG, Stovall M, Land CE
Epidemiology 2002 Sep;13(5):552-60. doi: 10.1097/00001648-200209000-00011. PMID: 12192225
Therapy-related megakaryoblastic leukemia with pituitary involvement following treatment for non-Hodgkin's lymphoma.
Saitoh T, Morimoto K, Kumagai T, Saiki M, Tanaka M, Aikawa S, Tsuboi I, Sawada U, Horie T
Intern Med 1999 Nov;38(11):904-9. doi: 10.2169/internalmedicine.38.904. PMID: 10563755
Pituitary function in patients receiving intermittent cytotoxic and corticosteroid therapy for malignant lymphoma.
Naysmith A, Hancock BW, Cullen DR, Richmond J, Wilde CE
Lancet 1976 Apr 3;1(7962):715-7. doi: 10.1016/s0140-6736(76)93090-7. PMID: 56533

Prognosis

Concomitant Primary CNS Lymphoma and FSH-Pituitary Adenoma Arising Within the Sella. Entirely Coincidental?
Ban VS, Chaudhary BR, Allinson K, Santarius T, Kirollos RW
Neurosurgery 2017 Jan 1;80(1):E170-E175. doi: 10.1093/neuros/nyw003. PMID: 28362886Free PMC Article
Hypophyseal metastases: A report of three cases and literature review.
Ravnik J, Smigoc T, Bunc G, Lanisnik B, Ksela U, Ravnik M, Velnar T
Neurol Neurochir Pol 2016 Nov-Dec;50(6):511-516. Epub 2016 Sep 4 doi: 10.1016/j.pjnns.2016.08.007. PMID: 27633123
Extranodal NK/T-cell lymphoma presenting as a pituitary mass. Case report and review of the literature.
Liu JK, Sayama C, Chin SS, Couldwell WT
J Neurosurg 2007 Sep;107(3):660-5. doi: 10.3171/JNS-07/09/0660. PMID: 17886569
Familial blood vessel tumors and subsequent cancers.
Ji J, Hemminki K
Ann Oncol 2007 Jul;18(7):1260-7. Epub 2007 Apr 10 doi: 10.1093/annonc/mdm092. PMID: 17426058
Lymphoma metastasizing to the pituitary: an unusual presentation of a treatable disease.
Megan Ogilvie C, Payne S, Evanson J, Lister TA, Grossman AB
Pituitary 2005;8(2):139-46. doi: 10.1007/s11102-005-4535-1. PMID: 16379034

Clinical prediction guides

Intravascular large B-cell lymphoma causing hypopituitarism and respiratory failure due to infiltration into pulmonary capillaries.
Kosaka T, Honda Y, Homma Y, Nakata M
BMJ Case Rep 2022 May 24;15(5) doi: 10.1136/bcr-2021-247880. PMID: 35609931Free PMC Article
Cancer incidence after nasopharyngeal radium irradiation.
Ronckers CM, Van Leeuwen FE, Hayes RB, Verduijn PG, Stovall M, Land CE
Epidemiology 2002 Sep;13(5):552-60. doi: 10.1097/00001648-200209000-00011. PMID: 12192225
Mortality following radiation treatment for infertility of hormonal origin or amenorrhoea.
Ron E, Boice JD Jr, Hamburger S, Stovall M
Int J Epidemiol 1994 Dec;23(6):1165-73. doi: 10.1093/ije/23.6.1165. PMID: 7721518
Growth retardation in childhood leukemia and lymphoma. Special reference to patients with CNS relapse.
Yamada S, Ishii E, Okabe Y, Kai T, Kuroiwa T, Hasuo K, Akazawa K, Tasaka H, Ueda K
Am J Pediatr Hematol Oncol 1992 Aug;14(3):236-40. doi: 10.1097/00043426-199208000-00010. PMID: 1510194
Prospective study on the influence of radiochemotherapy on pituitary function in children with acute leukaemia and NHL.
Kluba U, Mittler U, Mohnike K, Aumann V, Kröning G, Kapitza W, Röppnack R
Folia Haematol Int Mag Klin Morphol Blutforsch 1990;117(6):777-82. PMID: 1713881

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