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Crooke Cell Tumor

MedGen UID:
1667201
Concept ID:
C4727593
Neoplastic Process
Synonym: Crooke Cell Adenoma

Definition

A corticotroph pituitary tumor composed of cells with Crooke hyaline change. Ring-like cytokeratin expression is typical of these neoplasms. ACTH expression is dislocated to the cell periphery and juxtanuclear region. Ultrastructurally, intermediate filaments are arranged in a ring-like pattern. (WHO) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCrooke Cell Tumor

Professional guidelines

PubMed

Kontogeorgos G, Thodou E, Osamura RY, Lloyd RV
Hormones (Athens) 2022 Mar;21(1):1-14. Epub 2022 Jan 21 doi: 10.1007/s42000-021-00333-y. PMID: 35061210
Bracken RB, Swanson DA, Johnson DE, De Furia D, von Eschenbach AC, Crooke S
Urology 1980 Jul;16(1):11-5. doi: 10.1016/0090-4295(80)90322-2. PMID: 7395004

Recent clinical studies

Etiology

Zhu D, Wang Z, Tian T, Wu X, He D, Zhu Y, Liu D, Wang H
Front Endocrinol (Lausanne) 2022;13:947085. Epub 2022 Aug 19 doi: 10.3389/fendo.2022.947085. PMID: 36060980Free PMC Article
Kontogeorgos G, Thodou E, Osamura RY, Lloyd RV
Hormones (Athens) 2022 Mar;21(1):1-14. Epub 2022 Jan 21 doi: 10.1007/s42000-021-00333-y. PMID: 35061210
Giraldi EA, Neill SG, Mendoza P, Saindane A, Oyesiku NM, Ioachimescu AG
World Neurosurg 2022 Feb;158:e754-e765. Epub 2021 Nov 18 doi: 10.1016/j.wneu.2021.11.049. PMID: 34800730
Tatsi C, Stratakis CA
Rev Endocr Metab Disord 2020 Jun;21(2):213-223. doi: 10.1007/s11154-019-09534-8. PMID: 31912365
Mete O, Lopes MB
Endocr Pathol 2017 Sep;28(3):228-243. doi: 10.1007/s12022-017-9498-z. PMID: 28766057

Diagnosis

Zhu D, Wang Z, Tian T, Wu X, He D, Zhu Y, Liu D, Wang H
Front Endocrinol (Lausanne) 2022;13:947085. Epub 2022 Aug 19 doi: 10.3389/fendo.2022.947085. PMID: 36060980Free PMC Article
Hinojosa-Amaya JM, Lam-Chung CE, Cuevas-Ramos D
Front Endocrinol (Lausanne) 2021;12:657382. Epub 2021 Apr 26 doi: 10.3389/fendo.2021.657382. PMID: 33986726Free PMC Article
Schwann K, Bogiatzi C, Algird A, Lu JQ
J Clin Neurosci 2020 Mar;73:318-321. Epub 2020 Jan 11 doi: 10.1016/j.jocn.2020.01.014. PMID: 31937501
Todnem N, Ward A, Segar S, Rojiani AM, Rahimi SY
World Neurosurg 2018 Nov;119:197-200. Epub 2018 Aug 2 doi: 10.1016/j.wneu.2018.07.233. PMID: 30077745
Di Ieva A, Davidson JM, Syro LV, Rotondo F, Montoya JF, Horvath E, Cusimano MD, Kovacs K
Neurosurgery 2015 May;76(5):616-22. doi: 10.1227/NEU.0000000000000657. PMID: 25635886

Therapy

Tanaka S, Yamamoto M, Morita M, Takeno A, Kanazawa I, Yamaguchi T, Yamada S, Inoshita N, Oki Y, Kurosaki M, Sugimoto T
Endocr J 2019 Aug 29;66(8):701-708. Epub 2019 May 25 doi: 10.1507/endocrj.EJ18-0547. PMID: 31130573
Gilis-Januszewska A, Wilusz M, Pantofliński J, Turek-Jabrocka R, Sokołowski G, Sowa-Staszczak A, Kluczyński Ł, Pach D, Zieliński G, Hubalewska-Dydejczyk A
Endokrynol Pol 2018;69(3):306-312. Epub 2018 Jan 10 doi: 10.5603/EP.a2018.0011. PMID: 29319131
Rotondo F, Cusimano M, Scheithauer BW, Coire C, Horvath E, Kovacs K
Hormones (Athens) 2012 Jan-Mar;11(1):94-100. doi: 10.1007/BF03401542. PMID: 22450349
Issell BF, Crooke ST
Cancer Treat Rev 1979 Jun;6(2):107-24. doi: 10.1016/s0305-7372(79)80045-6. PMID: 385138
Crooke ST, Bradner WT
J Med 1976;7(5):333-428. PMID: 64579

Prognosis

Osamura RY, Inomoto C, Tahara S, Oyama KI, Matsuno A, Teramoto A
Appl Immunohistochem Mol Morphol 2023 Aug 1;31(7):485-489. Epub 2022 Oct 17 doi: 10.1097/PAI.0000000000001070. PMID: 36251979
Hernández-Ramírez LC
Rev Invest Clin 2022;74(5):244-257. doi: 10.24875/RIC.22000184. PMID: 36328029
Giraldi EA, Neill SG, Mendoza P, Saindane A, Oyesiku NM, Ioachimescu AG
World Neurosurg 2022 Feb;158:e754-e765. Epub 2021 Nov 18 doi: 10.1016/j.wneu.2021.11.049. PMID: 34800730
Yamamoto M, Nakao T, Ogawa W, Fukuoka H
Front Endocrinol (Lausanne) 2021;12:650791. Epub 2021 Jun 16 doi: 10.3389/fendo.2021.650791. PMID: 34220707Free PMC Article
Di Ieva A, Davidson JM, Syro LV, Rotondo F, Montoya JF, Horvath E, Cusimano MD, Kovacs K
Neurosurgery 2015 May;76(5):616-22. doi: 10.1227/NEU.0000000000000657. PMID: 25635886

Clinical prediction guides

Osamura RY, Inomoto C, Tahara S, Oyama KI, Matsuno A, Teramoto A
Appl Immunohistochem Mol Morphol 2023 Aug 1;31(7):485-489. Epub 2022 Oct 17 doi: 10.1097/PAI.0000000000001070. PMID: 36251979
Kontogeorgos G, Thodou E, Osamura RY, Lloyd RV
Hormones (Athens) 2022 Mar;21(1):1-14. Epub 2022 Jan 21 doi: 10.1007/s42000-021-00333-y. PMID: 35061210
Akirov A, Larouche V, Shimon I, Asa SL, Mete O, Sawka AM, Gentili F, Ezzat S
Front Endocrinol (Lausanne) 2021;12:620005. Epub 2021 Mar 18 doi: 10.3389/fendo.2021.620005. PMID: 33815279Free PMC Article
Doğanşen SÇ, Bilgiç B, Yalin GY, Tanrikulu S, Yarman S
Turk Patoloji Derg 2019;35(1):9-14. doi: 10.5146/tjpath.2018.01434. PMID: 30035294
Gilis-Januszewska A, Wilusz M, Pantofliński J, Turek-Jabrocka R, Sokołowski G, Sowa-Staszczak A, Kluczyński Ł, Pach D, Zieliński G, Hubalewska-Dydejczyk A
Endokrynol Pol 2018;69(3):306-312. Epub 2018 Jan 10 doi: 10.5603/EP.a2018.0011. PMID: 29319131

Recent systematic reviews

Findlay MC, Drexler R, Azab M, Karbe A, Rotermund R, Ricklefs FL, Flitsch J, Smith TR, Kilgallon JL, Honegger J, Nasi-Kordhishti I, Gardner PA, Gersey ZC, Abdallah HM, Jane JA Jr, Marino AC, Knappe UJ, Uksul N, Rzaev JA, Bervitskiy AV, Schroeder HWS, Eördögh M, Losa M, Mortini P, Gerlach R, Antunes ACM, Couldwell WT, Budohoski KP, Rennert RC, Karsy M
World Neurosurg 2023 Dec;180:e376-e391. Epub 2023 Sep 25 doi: 10.1016/j.wneu.2023.09.076. PMID: 37757948

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